DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cg and znf341

DIOPT Version :9

Sequence 1:	NP_001097306.2	Gene:	cg / 36571	FlyBaseID:	FBgn0000289	Length:	837	Species:	Drosophila melanogaster
Sequence 2:	XP_004918579.2	Gene:	znf341 / 100497785	XenbaseID:	XB-GENE-960338	Length:	849	Species:	Xenopus tropicalis

Alignment Length:	473	Identity:	112/473 - (23%)
Similarity:	176/473 - (37%)	Gaps:	140/473 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 CNEILIKRAIAAGHHQTHTITAADGSHHHASGGTPSFCSVGGATTLLGDILPGISVQV------- 238
            |.....:::....|.|||.:...:.:                 ||   ..|..:||||
Frog   357 CGRAFAQKSNVKKHMQTHKVWPREQN-----------------TT---KSLAPVSVQVLPLNPSQ 401

  Fly   239 --QKVIQGLEDNEDSQGEAP--NLKLEPGTLELSPKTE----LQESMHF----SETDATI----- 286
              :||.:...:::....|||  .:::.||::...|..:    :..|.|.    |:.|:..
Frog   402 AQEKVAENGANSQPPTEEAPAEGMEVAPGSMGEGPDAKHVVLVDSSYHCQFCPSKFDSYFQLKSH 466

  Fly   287 ----KKERPYSC--DECGKSFLLKHHLTTHARVHTGERPHICTHCGKSFA---------HKHCLN 336
                |:|:.|.|  ..||.:.....|...|.:.|..|..:.|..|.|..|         :.||:.
Frog   467 MTQHKQEQVYKCVVKGCGHTSQKLDHFLEHIKTHQEELTYRCHLCNKDCASLYEMGVHQYSHCML 531

  Fly   337 THLLLHSTERPYQCQECKKSFT----LKHHLLTHSRVHSRERPFVCQECGRAFPLKRHLVTHSKF 397
            ..:.....:..|:|.:|...::    |:.||.|  ..||    :.|..|.:.||.:|:|..|...
Frog   532 PQITPKKDQAVYKCLKCMNKYSTPEALEQHLQT--ATHS----YPCPHCPKVFPCERYLRRHLPT 590

  Fly   398 HAGERPYVCEECGESFAQENHLIMHSRFHGSLNPFVCAECGASFPRKFQLVNHGRIHGKIPH--- 459
            |.|...|.|..|.:.|.:|::|.:||..|....||.||.|.::|.||.:|..|..||  :|:
Frog   591 HGGGGRYKCPICKKLFRREHYLKLHSHIHSGEKPFRCALCDSAFNRKDKLKRHMLIH--VPYKKY 653

  Fly   460 ------SCTVCGKEFLQKRTLVSHMRRVHTGEQAHPCVSCGEGFLTKAELHQHVRTAHNGVNPNT 518
                  |.|.|.|||.:...|.:||.. |:|.:.|.|..|.:.|..:|.:.:|.|
Frog   654 KCPFSRSHTGCNKEFNRPDKLKAHMLS-HSGIKTHKCQYCSKSFSRRAHMVEHQR---------- 707

  Fly   519 SSATIIANQQLQQAHHHQAGQQTHPQTITVVSNPGNSTLLTVSTTDANGVARPQFVCRECGSAFN 583
                                           |:.||.                ::.|..||..|.
Frog   708 -------------------------------SHTGNY----------------RYSCPNCGKGFT 725

  Fly   584 SREALALH-LRLHT-GDK 599
            .::.:..| .|||: |||
Frog   726 RQKYMKEHKCRLHSDGDK 743

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cg	NP_001097306.2	COG5048	287..>371	CDD:227381	23/98 (23%)
		C2H2 Zn finger	294..314	CDD:275368	5/21 (24%)
		zf-H2C2_2	306..331	CDD:290200	8/33 (24%)
		C2H2 Zn finger	322..342	CDD:275368	6/28 (21%)
		C2H2 Zn finger	350..370	CDD:275368	6/23 (26%)
		zf-H2C2_2	362..385	CDD:290200	7/22 (32%)
		C2H2 Zn finger	378..398	CDD:275368	7/19 (37%)
		zf-H2C2_2	390..415	CDD:290200	8/24 (33%)
		C2H2 Zn finger	406..426	CDD:275368	7/19 (37%)
		SIR2	<425..>465	CDD:294129	16/48 (33%)
		C2H2 Zn finger	434..454	CDD:275368	8/19 (42%)
		C2H2 Zn finger	461..482	CDD:275368	8/20 (40%)
		C2H2 Zn finger	490..509	CDD:275368	5/18 (28%)
		lambda-1	491..>603	CDD:212564	19/111 (17%)
		C2H2 Zn finger	575..595	CDD:275368	6/20 (30%)
		C2H2 Zn finger	720..740	CDD:275368
		C2H2 Zn finger	752..771	CDD:275368
znf341	XP_004918579.2	C2H2 Zn finger	326..346	CDD:275368
		zf-H2C2_2	338..363	CDD:404364	1/5 (20%)
		COG5048	342..705	CDD:227381	96/376 (26%)
		C2H2 Zn finger	354..374	CDD:275368	3/16 (19%)
		C2H2 Zn finger	450..470	CDD:275368	2/19 (11%)
		C2H2 Zn finger	478..500	CDD:275368	5/21 (24%)
		C2H2 Zn finger	508..528	CDD:275368	4/19 (21%)
		C2H2 Zn finger	545..567	CDD:275370	6/23 (26%)
		C2H2 Zn finger	571..591	CDD:275368	7/19 (37%)
		C2H2 Zn finger	599..619	CDD:275368	7/19 (37%)
		C2H2 Zn finger	627..647	CDD:275368	8/19 (42%)
		C2H2 Zn finger	655..681	CDD:275368	9/26 (35%)
		C2H2 Zn finger	689..709	CDD:275368	6/60 (10%)
		C2H2 Zn finger	717..738	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100