DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ReepB and Reep4

DIOPT Version :9

Sequence 1:	NP_001188928.1	Gene:	ReepB / 36569	FlyBaseID:	FBgn0033906	Length:	178	Species:	Drosophila melanogaster
Sequence 2:	XP_006519661.1	Gene:	Reep4 / 72549	MGIID:	1919799	Length:	293	Species:	Mus musculus

Alignment Length:	140	Identity:	37/140 - (26%)
Similarity:	63/140 - (45%)	Gaps:	41/140 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 LLCNII----GVLYPAYISIHAIESSTKQDDTKWLIYWVTFGIFTVIEFFSS------------- 112
            ::|.::    |:|||||.|..|::|...::..:|::||:.|.||...|.|:.
Mouse     5 MICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWSGPRIGRP 69

  Fly   113 -----------------------LLTSVIPFYWLLKCAFLIWCMLPTEQNGSTIIYNKLVRPYFL 154
                                   |||...|||:..|.||::|.:.|..: |::::|.|.|.|...
Mouse    70 WGWEGPHHHHHHHLASGSHKPLPLLTHRFPFYYEFKMAFVLWLLSPYTK-GASLLYRKFVHPSLS 133

  Fly   155 KHHESVDRII 164
            :|.:.:|..|
Mouse   134 RHEKEIDACI 143

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ReepB	NP_001188928.1	TB2_DP1_HVA22	63..151	CDD:281172	33/125 (26%)
Reep4	XP_006519661.1	TB2_DP1_HVA22	19..130	CDD:367349	29/111 (26%)
Reep4	XP_006519661.1	PRK11675	<247..>279	CDD:183272
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1473891at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820