Protein Alignment CG18324 and SLC25A14

DIOPT Version :10

• Sequence 1: NP_725361.1
• Gene: CG18324 / 36568
• FlyBaseID: FBgn0033905
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_001269126.1
• Gene: SLC25A14 / 9016
• HGNCID: 10984
• Length: 353
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 95/329 - (28%)
• Similarity: 154/329 - (46%)
• Gaps: 54/329 - (16%)

  Fly     6 FVLGGTAAMGAVVFTNPIDVVKTRMQLQGE-LAARGTYVKPYRHLPQAMLQIVLNDGLLALEKGL 69
            ||.||.|::.|...|.|:|:.|||:|:||: :.||...:| ||.:..|:.:|...:|:|||..|:
Human    41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIK-YRGMFHALFRICKEEGVLALYSGI 104

  Fly    70 APALCYQFVLNSVRLSVYSNALELGYLQNADGSISFYRGMFFGALGGCTGTYFASPFYMIKAQQH 134
            ||||..|....::::.:|.:...|...:..|.::..  .|..|.:.|...:..|:|..::|.:..
Human   105 APALLRQASYGTIKIGIYQSLKRLFVERLEDETLLI--NMICGVVSGVISSTIANPTDVLKIRMQ 167

  Fly   135 AQAVQSIAVGFQHKHTSMMDALLHIYRTNGISGFWR----------------------------- 170
            ||.  |:..|      ||:.:.:.||:..|..|.||
Human   168 AQG--SLFQG------SMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGS 224

  Fly   171 --AALPSLNRTLVASSVQIGTFPKAKSLLKDKGWITHPVLLSFCAGLSSGTLVAVANSPFDVLTT 233
              ..:|:..|..:...|::..:...|..|...|.:...:|..|.:..:.|...|:|::|.||:.|
Human   225 LEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGLAGALASNPVDVVRT 289

  Fly   234 RMYNQ-----PVDEKGRGLMYKGLVDCFTKIWRTEGIHGMYKGFWPIYFRSAPHTTLTFVFFEKL 293
            ||.||     .||      :|||.||...|:|:.||...:||||||.:.|..|...:.|:.:|:|
Human   290 RMMNQRAIVGHVD------LYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 348

  Fly   294 LHLR 297
            ..|:
Human   349 KRLQ 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18324	NP_725361.1	Mito_carr	4..87	CDD:395101	32/81 (40%)
		Mito_carr	101..201	CDD:395101	23/130 (18%)
		Mito_carr	204..296	CDD:395101	35/96 (36%)
SLC25A14	NP_001269126.1	Mito_carr	37..133	CDD:395101	34/92 (37%)
		Mito_carr	134..254	CDD:395101	23/129 (18%)
		Mito_carr	262..351	CDD:395101	35/94 (37%)