Protein Alignment CG18324 and UCP3

DIOPT Version :10

• Sequence 1: NP_725361.1
• Gene: CG18324 / 36568
• FlyBaseID: FBgn0033905
• Length: 307
• Species: Drosophila melanogaster
• Sequence 2: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 87/296 - (29%)
• Similarity: 132/296 - (44%)
• Gaps: 23/296 - (7%)

  Fly     6 FVLGGTAAMGAVVFTNPIDVVKTRMQLQGE-LAARGTYVKPYRHLPQAMLQIVLNDGLLALEKGL 69
            |:..||||..|.:.|.|:|..|.|:|:||| .|.:...:..||.:...:|.:|..:|..:...||
Human    17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGL 81

  Fly    70 APALCYQFVLNSVRLSVYSNALELGYLQNADGSISFYRGMFFGALGGCT----GTYFASPFYMIK 130
            ...|..|....|:|:.:|.:..::...:.||.|....|     .|.|||    ....|.|..::|
Human    82 VAGLQRQMSFASIRIGLYDSVKQVYTPKGADNSSLTTR-----ILAGCTTGAMAVTCAQPTDVVK 141

  Fly   131 AQQHAQAVQSIAVG---FQHKHTSMMDALLHIYRTNGISGFWRAALPSLNRTLVASSVQIGTFPK 192
            .:..|    ||.:|   ...|::..|||...|.|..|:.|.|:..||::.|..:.:..::.|:..
Human   142 VRFQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDI 202

  Fly   193 AKSLLKDKGWITHPVLLSFCAGLSSGTLVAVANSPFDVLTTRMYNQPVDEKGRGLMYKGLVDCFT 257
            .|..|.|...:|......|.:...:|....|..||.||:.||..|.|..:      |...:||..
Human   203 LKEKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNSPPGQ------YFSPLDCMI 261

  Fly   258 KIWRTEGIHGMYKGFWPIYFRSAPHTTLTFVFFEKL 293
            |:...||....||||.|.:.|......:.||.:|:|
Human   262 KMVAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18324	NP_725361.1	Mito_carr	4..87	CDD:395101	27/81 (33%)
		Mito_carr	101..201	CDD:395101	29/106 (27%)
		Mito_carr	204..296	CDD:395101	28/90 (31%)
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	28/92 (30%)
		Solcar 1	11..105		28/87 (32%)
		Mito_carr	112..210	CDD:395101	29/106 (27%)
		Solcar 2	114..206		27/100 (27%)
		Mito_carr	214..303	CDD:395101	28/90 (31%)
		Solcar 3	215..300		27/89 (30%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		5/19 (26%)