Protein Alignment CG18327 and UCP3

DIOPT Version :10

• Sequence 1: NP_610934.1
• Gene: CG18327 / 36567
• FlyBaseID: FBgn0033904
• Length: 304
• Species: Drosophila melanogaster
• Sequence 2: NP_003347.1
• Gene: UCP3 / 7352
• HGNCID: 12519
• Length: 312
• Species: Homo sapiens
• Alignment Length: 294
• Identity: 82/294 - (27%)
• Similarity: 138/294 - (46%)
• Gaps: 19/294 - (6%)

  Fly     6 FVLGGVAAMGAGVFTNPVEVIKTRIQLQGE-LAARGSHAQPYKSVFQAFVTVAKNDGILGLQKGL 69
            |:..|.||..|.:.|.|::..|.|:|:||| .|.:.:....|:.|....:|:.:.:|......||
Human    17 FLGAGTAACFADLVTFPLDTAKVRLQIQGENQAVQTARLVQYRGVLGTILTMVRTEGPCSPYNGL 81

  Fly    70 APALCFQFVINSFRLSIYTHAVEKGWVHNNKG--EISFAKGMFWGALGGVVGSYCASPFFLIKTQ 132
            ...|..|....|.|:.:|....:   |:..||  ..|....:..|...|.:...||.|..::|.:
Human    82 VAGLQRQMSFASIRIGLYDSVKQ---VYTPKGADNSSLTTRILAGCTTGAMAVTCAQPTDVVKVR 143

  Fly   133 LQAQAAKQIAVG---YQHQHASMSDAIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAK 194
            .||    .|.:|   ...:::...||.|.|.|:.||.|||:|:|.|:.|..:.:..::..:...|
Human   144 FQA----SIHLGPSRSDRKYSGTMDAYRTIAREEGVRGLWKGTLPNIMRNAIVNCAEVVTYDILK 204

  Fly   195 SLLKENGVVTHPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRGIYYRGWLDCVLTI 259
            ..|.:..::|......|.|...||...::..:|:|||.||..|     ...|.|:.. |||::.:
Human   205 EKLLDYHLLTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMN-----SPPGQYFSP-LDCMIKM 263

  Fly   260 LRSEGVYGLYKGFWPIYLRSAPYSTLVLLFFDEL 293
            :..||....||||.|.:||...::.::.:.:::|
Human   264 VAQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQL 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18327	NP_610934.1	PTZ00169	5..293	CDD:240302	81/292 (28%)
UCP3	NP_003347.1	Mito_carr	10..110	CDD:395101	26/95 (27%)
		Solcar 1	11..105		25/90 (28%)
		Mito_carr	112..210	CDD:395101	27/101 (27%)
		Solcar 2	114..206		26/95 (27%)
		Mito_carr	214..303	CDD:395101	27/90 (30%)
		Solcar 3	215..300		26/89 (29%)
		Purine nucleotide binding. /evidence=ECO:0000250	279..301		3/19 (16%)