DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG18327 and UCP1

DIOPT Version :9

Sequence 1:NP_001260966.1 Gene:CG18327 / 36567 FlyBaseID:FBgn0033904 Length:304 Species:Drosophila melanogaster
Sequence 2:NP_068605.1 Gene:UCP1 / 7350 HGNCID:12517 Length:307 Species:Homo sapiens


Alignment Length:284 Identity:75/284 - (26%)
Similarity:128/284 - (45%) Gaps:12/284 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 GVAAMGAGVFTNPVEVIKTRIQLQGELAARGSHAQPYKSVFQAFVTVAKNDGILGLQKGLAPALC 74
            |:||..|.|.|.|::..|.|:|:|||...  |....||.|......|.|.:|.:.|..||...|.
Human    21 GIAACLADVITFPLDTAKVRLQVQGECPT--SSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQ 83

  Fly    75 FQFVINSFRLSIYTHAVEKGWVHNNKGEISFAKGMFWGALGGVVGSYCASPFFLIKTQLQAQAAK 139
            .|....|.|:.:| ..|::......:...|....:..|...|.|..:...|..::|.:||||:..
Human    84 RQISSASLRIGLY-DTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHL 147

  Fly   140 QIAVGYQHQHASMSDAIRKIYRKNGVFGLWRGSLANVSRATVASAVQIAVFGQAKSLLKENGVVT 204
            .   |.:.::....:|.|.|....|:.|||:|:..|:.|:.:.:..::..:...|....:|.::.
Human   148 H---GIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILA 209

  Fly   205 HPTILSFCSGLAAGSFVSLAITPLDVVTTRLYNQGVDAQGRGIYYRGWLDCVLTILRSEGVYGLY 269
            ........|.|.||...:...:|:|||.||..|   ...|:   |:...:|.:.:..:||....:
Human   210 DDVPCHLVSALIAGFCATAMSSPVDVVKTRFIN---SPPGQ---YKSVPNCAMKVFTNEGPTAFF 268

  Fly   270 KGFWPIYLRSAPYSTLVLLFFDEL 293
            ||..|.:||...::.::.:.|::|
Human   269 KGLVPSFLRLGSWNVIMFVCFEQL 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG18327NP_001260966.1 Mito_carr 4..87 CDD:278578 27/76 (36%)
PTZ00169 5..293 CDD:240302 74/282 (26%)
Mito_carr 101..201 CDD:278578 22/99 (22%)
Mito_carr 204..296 CDD:278578 23/90 (26%)
UCP1NP_068605.1 Mito_carr 10..104 CDD:278578 29/85 (34%)
Solcar 1 11..102 29/83 (35%)
Mito_carr 111..206 CDD:278578 22/97 (23%)
Solcar 2 111..201 22/92 (24%)
Solcar 3 210..295 23/89 (26%)
Mito_carr 215..300 CDD:278578 23/84 (27%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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