DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8323 and SLC25A14

DIOPT Version :9

Sequence 1:NP_610933.1 Gene:CG8323 / 36566 FlyBaseID:FBgn0033903 Length:303 Species:Drosophila melanogaster
Sequence 2:NP_001269126.1 Gene:SLC25A14 / 9016 HGNCID:10984 Length:353 Species:Homo sapiens


Alignment Length:324 Identity:95/324 - (29%)
Similarity:166/324 - (51%) Gaps:52/324 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 FVLGGLASVGATFFTNPIEVIKTRIQLQGE-LAARGTYVEPYKGIVNAFITVAKNDGITGLQKGL 69
            ||.|||||:.|.|.|.|:::.|||:|:||: :.||...:: |:|:.:|...:.|.:|:..|..|:
Human    41 FVYGGLASIVAEFGTFPVDLTKTRLQVQGQSIDARFKEIK-YRGMFHALFRICKEEGVLALYSGI 104

  Fly    70 APALYFQFIINSFRLSIYSEAMERRWMHNRKGEVSYGMGLLWGAIGGVVGCYFSSPFFLIKTQLQ 134
            ||||..|....:.::.|| ::::|.::...:.|... :.::.|.:.||:....::|..::|.::|
Human   105 APALLRQASYGTIKIGIY-QSLKRLFVERLEDETLL-INMICGVVSGVISSTIANPTDVLKIRMQ 167

  Fly   135 SQAAKQIAVGYQHAHTSMTDALRQIYSRNGVRGLWR----------------------------- 170
            :|.:.     :|   .||..:...||.:.|.|||||                             
Human   168 AQGSL-----FQ---GSMIGSFIDIYQQEGTRGLWRCLCSKAVTGCVLWLMPVIPALWEANAGGS 224

  Fly   171 --GSVAALPRAALGSGAQIATFGKTKALLV----QYDLVTQPTLNSFSAGLIAGSIMSVAITPPD 229
              |.|....|||:..|.::..:..||..|:    ..|.:....::||:.|| ||::.|   .|.|
Human   225 LEGVVPTAQRAAIVVGVELPVYDITKKHLILSGMMGDTILTHFVSSFTCGL-AGALAS---NPVD 285

  Fly   230 VITTRLYNQGVDAEGRGLLYRGWLDCFVKILRSEGVYGMYKGFWANYLRIAPHSTLVLLFFDEL 293
            |:.||:.||.. ..|...||:|.:|..:|:.:.||.:.:|||||.|:||:.|.:.:..:.:::|
Human   286 VVRTRMMNQRA-IVGHVDLYKGTVDGILKMWKHEGFFALYKGFWPNWLRLGPWNIIFFITYEQL 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8323NP_610933.1 Mito_carr 4..87 CDD:278578 31/81 (38%)
PTZ00169 5..293 CDD:240302 94/322 (29%)
Mito_carr 101..200 CDD:278578 28/133 (21%)
Mito_carr 206..301 CDD:278578 32/88 (36%)
SLC25A14NP_001269126.1 Mito_carr 37..133 CDD:278578 34/93 (37%)
PTZ00169 41..351 CDD:240302 95/324 (29%)
Mito_carr 134..254 CDD:278578 27/128 (21%)
Mito_carr 262..351 CDD:278578 32/92 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R857
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.940

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