Protein Alignment CG8323 and UCP1

DIOPT Version :10

• Sequence 1: NP_610933.1
• Gene: CG8323 / 36566
• FlyBaseID: FBgn0033903
• Length: 303
• Species: Drosophila melanogaster
• Sequence 2: NP_068605.1
• Gene: UCP1 / 7350
• HGNCID: 12517
• Length: 307
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 74/284 - (26%)
• Similarity: 135/284 - (47%)
• Gaps: 12/284 - (4%)

  Fly    10 GLASVGATFFTNPIEVIKTRIQLQGELAARGTYVEPYKGIVNAFITVAKNDGITGLQKGLAPALY 74
            |:|:..|...|.|::..|.|:|:|||...  :.|..|||::.....|.|.:|...|..||...|.
Human    21 GIAACLADVITFPLDTAKVRLQVQGECPT--SSVIRYKGVLGTITAVVKTEGRMKLYSGLPAGLQ 83

  Fly    75 FQFIINSFRLSIYSEAMERRWMHNRKGEVSYGMGLLWGAIGGVVGCYFSSPFFLIKTQLQSQAAK 139
            .|....|.|:.:| :.::......::...|.|..:|.|...|.|..:...|..::|.:||:|:..
Human    84 RQISSASLRIGLY-DTVQEFLTAGKETAPSLGSKILAGLTTGGVAVFIGQPTEVVKVRLQAQSHL 147

  Fly   140 QIAVGYQHAHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQIATFGKTKALLVQYDLVT 204
            .   |.:..:|...:|.|.|.:..|:.|||:|:...|.|:.:.:..::.|:...|...|:.:::.
Human   148 H---GIKPRYTGTYNAYRIIATTEGLTGLWKGTTPNLMRSVIINCTELVTYDLMKEAFVKNNILA 209

  Fly   205 QPTLNSFSAGLIAGSIMSVAITPPDVITTRLYNQGVDAEGRGLLYRGWLDCFVKILRSEGVYGMY 269
            ........:.||||...:...:|.||:.||..|   ...|:   |:...:|.:|:..:||....:
Human   210 DDVPCHLVSALIAGFCATAMSSPVDVVKTRFIN---SPPGQ---YKSVPNCAMKVFTNEGPTAFF 268

  Fly   270 KGFWANYLRIAPHSTLVLLFFDEL 293
            ||...::||:...:.::.:.|::|
Human   269 KGLVPSFLRLGSWNVIMFVCFEQL 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8323	NP_610933.1	PTZ00169	5..293	CDD:240302	73/282 (26%)
UCP1	NP_068605.1	Mito_carr	10..104	CDD:395101	26/85 (31%)
		Solcar 1	11..102		26/83 (31%)
		Mito_carr	111..206	CDD:395101	26/97 (27%)
		Solcar 2	111..201		25/92 (27%)
		Solcar 3	210..295		22/89 (25%)
		Mito_carr	215..300	CDD:395101	22/84 (26%)