DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8323 and ucp2

DIOPT Version :9

Sequence 1:	NP_610933.1	Gene:	CG8323 / 36566	FlyBaseID:	FBgn0033903	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_571251.1	Gene:	ucp2 / 555812	ZFINID:	ZDB-GENE-990708-8	Length:	310	Species:	Danio rerio

Alignment Length:	299	Identity:	85/299 - (28%)
Similarity:	141/299 - (47%)	Gaps:	23/299 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ATSDFVLGGLASVGATFFTNPIEVIKTRIQLQGELAA-----RGTYVEPYKGIVNAFITVAKNDG 61
            ||..|:..|.|:..|..||.|::..|.|:|:|||..|     ||..  .|:|:.....|:.:.:|
Zfish    13 ATVKFIGAGTAACIADLFTFPLDTAKVRLQIQGENKASTNMGRGPV--KYRGVFGTISTMVRVEG 75

  Fly    62 ITGLQKGLAPALYFQFIINSFRLSIYSEAMERRWMHNRKGEVSYGMG--LLWGAIGGVVGCYFSS 124
            ...|..||...|..|....|.|:.:|....:    ...||....|:|  |:.|...|.:....:.
Zfish    76 PRSLYSGLVAGLQRQMSFASVRIGLYDSVKQ----FYTKGSDHAGIGSRLMAGCTTGAMAVAVAQ 136

  Fly   125 PFFLIKTQLQSQAAKQIAVGYQHAHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQIAT 189
            |..::|.:.|:    |::.|....:.|..||.|.|....|.||||:|:...:.|.|:.:..::.|
Zfish   137 PTDVVKVRFQA----QVSAGSSKRYHSTMDAYRTIAKEEGFRGLWKGTGPNITRNAIVNCTELVT 197

  Fly   190 FGKTKALLVQYDLVTQPTLNSFSAGLIAGSIMSVAITPPDVITTRLYNQGVDAEGRGLLYRGWLD 254
            :...|..|::..|:|......|::...||...::..:|.||:.||..|   .|:|:   |...|:
Zfish   198 YDLIKDALLKSSLMTDDLPCHFTSAFGAGFCTTIIASPVDVVKTRYMN---SAQGQ---YSSALN 256

  Fly   255 CFVKILRSEGVYGMYKGFWANYLRIAPHSTLVLLFFDEL 293
            |.|.:|..||....||||..::||:...:.::.:.:::|
Zfish   257 CAVAMLTKEGPKAFYKGFMPSFLRLGSWNVVMFVTYEQL 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8323	NP_610933.1	Mito_carr	4..87	CDD:278578	27/87 (31%)
		PTZ00169	5..293	CDD:240302	82/294 (28%)
		Mito_carr	101..200	CDD:278578	27/100 (27%)
		Mito_carr	206..301	CDD:278578	25/88 (28%)
ucp2	NP_571251.1	Mito_carr	10..112	CDD:278578	31/104 (30%)
		Solcar 1	11..107		30/99 (30%)
		PTZ00169	17..300	CDD:240302	83/295 (28%)
		Mito_carr	113..209	CDD:278578	26/99 (26%)
		Solcar 2	115..204		25/92 (27%)
		Solcar 3	213..298		25/89 (28%)
		Mito_carr	218..300	CDD:278578	25/84 (30%)
		Purine nucleotide binding. /evidence=ECO:0000250	277..299		3/19 (16%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910