DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8323 and oac1

DIOPT Version :9

Sequence 1:	NP_610933.1	Gene:	CG8323 / 36566	FlyBaseID:	FBgn0033903	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_593169.1	Gene:	oac1 / 2541790	PomBaseID:	SPAC139.02c	Length:	320	Species:	Schizosaccharomyces pombe

Alignment Length:	297	Identity:	112/297 - (37%)
Similarity:	170/297 - (57%)	Gaps:	20/297 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SDFVLGGLASVGATFFTNPIEVIKTRIQLQGELAARGTYVEP----YKGIVNAFITVAKNDGITG 64
            |.|:.||||:.||...|||.||||||.||||:|    |.::|    ||.:..||..:|:::||.|
pombe    25 SGFLSGGLAACGAVTLTNPFEVIKTRFQLQGQL----TKLDPSKRIYKSVGQAFSLIARHEGIRG 85

  Fly    65 LQKGLAPALYFQFIINSFRLSIYSEAMER---RW-MHNRKGEVSYGMGLLWGAIGGVVGCYFSSP 125
            ||:||..|..:|..:|..||..| |.:.|   .| :.:.||. ...:.:..||..|:.|..|.||
pombe    86 LQRGLGTAYVYQICLNGCRLGFY-EPIRRTLNTWFLDDPKGN-KLAINVASGAGSGLCGALFGSP 148

  Fly   126 FFLIKTQLQSQAAKQIAVGYQHAHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQIATF 190
            |||:||::||.:.| ..||.|:.:..:.:|..:|...|||:||:.|:.||:.|...||..|:..:
pombe   149 FFLVKTRMQSYSPK-FPVGQQYGYKHIFNAFSRIIKENGVKGLFVGADAAILRTVSGSSVQLPIY 212

  Fly   191 GKTKALLVQYDLVTQPTLNSFSAGLIAGSIMSVAITPPDVITTRLYNQGVDAEGRGLLYRGWLDC 255
            ...|.::..|:|:.:..:...:|..::|..:...:...|.:.||:||| .:.|    ||:..:||
pombe   213 NWAKRMIEHYNLLEEGMIKHLTASAVSGFGVCCTMQIFDTVMTRMYNQ-KNKE----LYKNPIDC 272

  Fly   256 FVKILRSEGVYGMYKGFWANYLRIAPHSTLVLLFFDE 292
            .:|.:||||.:.:||||.|:..|||||:...|.|.::
pombe   273 ILKTIRSEGFFALYKGFGAHLARIAPHTIFCLTFVEQ 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8323	NP_610933.1	Mito_carr	4..87	CDD:278578	41/86 (48%)
		PTZ00169	5..293	CDD:240302	111/296 (38%)
		Mito_carr	101..200	CDD:278578	34/98 (35%)
		Mito_carr	206..301	CDD:278578	30/87 (34%)
oac1	NP_593169.1	PTZ00169	19..295	CDD:240302	105/281 (37%)
		Mito_carr	19..117	CDD:278578	44/96 (46%)
		Mito_carr	127..223	CDD:278578	33/96 (34%)
		Mito_carr	226..316	CDD:278578	30/89 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	83	1.000	Domainoid score	I2246
eggNOG	1	0.900	-	-		E1_KOG0755
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68806
Inparanoid	1	1.050	186	1.000	Inparanoid score	I1068
OMA	1	1.010	-	-		QHG53880
OrthoFinder	1	1.000	-	-		FOG0001815
OrthoInspector	1	1.000	-	-		otm47162
orthoMCL	1	0.900	-	-		OOG6_102209
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	1	1.000	-	-		X1023
TreeFam	1	0.960	-	-
	13	12.760