DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8323 and SLC25A10

DIOPT Version :9

Sequence 1:	NP_610933.1	Gene:	CG8323 / 36566	FlyBaseID:	FBgn0033903	Length:	303	Species:	Drosophila melanogaster
Sequence 2:	NP_001257882.1	Gene:	SLC25A10 / 1468	HGNCID:	10980	Length:	406	Species:	Homo sapiens

Alignment Length:	184	Identity:	51/184 - (27%)
Similarity:	91/184 - (49%)	Gaps:	12/184 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SDFVLGGLASVGATFFTNPIEVIKTRIQLQGELAARGTYVEPYKGIVNAFITVAKNDGITGLQKG 68
            |.:..|||||.||...|:|::::|..:|.|.|:..|.|      |:.   :.|.:.|||..|..|
Human     8 SRWYFGGLASCGAACCTHPLDLLKVHLQTQQEVKLRMT------GMA---LRVVRTDGILALYSG 63

  Fly    69 LAPALYFQFIINSFRLSIYSEAMERRWMHNRKGEVSYGMGLLWGAIGGVVGCYFSSPFFLIKTQL 133
            |:.:|..|...:..|.:|| |.:..|.....:|.:.:...:|.|::.|:.|.:..:|..|:..::
Human    64 LSASLCRQMTYSLTRFAIY-ETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGTPADLVNVRM 127

  Fly   134 QSQAAKQIAVGYQHAHTSMTDALRQIYSRNGVRGLWRGSVAALPRAALGSGAQI 187
            |:..  ::..|.:..:....|.|.::....|:|.|:.|:..|..|.||.:..|:
Human   128 QNDV--KLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQL 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8323	NP_610933.1	Mito_carr	4..87	CDD:278578	27/82 (33%)
		PTZ00169	5..293	CDD:240302	50/183 (27%)
		Mito_carr	101..200	CDD:278578	20/87 (23%)
		Mito_carr	206..301	CDD:278578
SLC25A10	NP_001257882.1	Mito_carr	13..93	CDD:278578	30/89 (34%)
SLC25A10	NP_001257882.1	Mito_carr	95..179	CDD:278578	19/85 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R857
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.940