DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3m and AT3G02200

DIOPT Version :9

Sequence 1:	NP_001286407.1	Gene:	eIF3m / 36565	FlyBaseID:	FBgn0033902	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_186869.2	Gene:	AT3G02200 / 821267	AraportID:	AT3G02200	Length:	417	Species:	Arabidopsis thaliana

Alignment Length:	368	Identity:	100/368 - (27%)
Similarity:	189/368 - (51%)	Gaps:	46/368 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ISSEKSNKGVEDDLHKIIGVCDVCFKDGEPSQIDGILNSIVSIMITIPLDRGENIVLAYCEKMTK 94
            :||:.|.|.:| ..:.||  |.:......|.|:..::.:|.|.:...|.|:
plant    67 VSSKISEKDLE-CTYTII--CSIVKNAKSPEQVLEMVKAIASKVAQQPSDK-------------- 114

  Fly    95 APNLPLGKVCLQSLWRLFNNLDTASP-LRYHVYYHLVQVA---KQCEQVLEVFSGVDQLKSQFAN 155
                  ..:.|:.|:.|:|.:|  .| .|:.||...:.:|   |..|.::..|..:|....:: |
plant   115 ------ASLRLKILFNLYNLVD--HPYARFQVYMKALTLAVDGKVTEYIVSSFKKIDNFLKEW-N 170

  Fly   156 CPPSSEQMQKLYRLLHDVTKDTN--LELSSKVMIELLGTYTADNACV---AREDAMKCIVTALAD 215
            .  ..:..::|:..:.:|.|:..  :..|.|.:.:.|.|::.::|.|   |:|:|::.::..:..
plant   171 I--DIKDQRELFLAIANVLKENKSLVNESLKFLTKYLATFSNEDAQVLDEAKEEAVRAVIEFVKA 233

  Fly   216 PNTFLLDPLLSLKPVRFLEGDL----IHDLLSIFVSEKLPAYVQFYEDHREFVNSQGLNHEQNMK 276
            .:.|..| ||.|..|..||.|.    ::.||.||::::|.||.:|...:..|:.|.||::|..:.
plant   234 SSIFQCD-LLDLPAVAQLEKDAKYAPVYQLLKIFLTQRLNAYTEFQNANSGFLQSYGLSNEDCVT 297

  Fly   277 KMRLLTFMQLA-ESSPEMTFETLTKELQINEDEVEPFVIEVLKTKLVRARLDQANQKVHISSTMH 340
            |||||:.:.|| :.|.::.:.::...||:||.:||.::::.:..||:..::||.||.:.:|.:..
plant   298 KMRLLSLVDLASDESGKIPYTSIKDTLQVNEQDVELWIVKAITAKLIECKMDQMNQVLIVSRSSE 362

  Fly   341 RTFGAPQWEQLRDLLQAWKENLSTVREGLTSVSSAQLDLARSQ 383
            |.||..||:.||..|..||:|:|::   :|::.|.::....||
plant   363 REFGTKQWQSLRTKLATWKDNISSI---ITTIESNKVTEEGSQ 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3m	NP_001286407.1	PCI	236..336	CDD:396121	34/104 (33%)
eIF3m	NP_001286407.1	eIF3m_C_helix	341..369	CDD:407846	12/27 (44%)
AT3G02200	NP_186869.2	PCI	258..359	CDD:396121	33/100 (33%)
AT3G02200	NP_186869.2	eIF3m_C_helix	363..391	CDD:407846	13/30 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	73	1.000	Domainoid score	I3281
eggNOG	1	0.900	-	-		E1_KOG2753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4639
Inparanoid	1	1.050	125	1.000	Inparanoid score	I1939
OMA	1	1.010	-	-		QHG54703
OrthoDB	1	1.010	-	-		D679771at2759
OrthoFinder	1	1.000	-	-		FOG0005091
OrthoInspector	1	1.000	-	-		otm2658
orthoMCL	1	0.900	-	-		OOG6_103094
Panther	1	1.100	-	-	O	PTHR15350
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840