DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment eIF3m and CSN7

DIOPT Version :9

Sequence 1:	NP_001286407.1	Gene:	eIF3m / 36565	FlyBaseID:	FBgn0033902	Length:	387	Species:	Drosophila melanogaster
Sequence 2:	NP_610379.2	Gene:	CSN7 / 35816	FlyBaseID:	FBgn0028836	Length:	278	Species:	Drosophila melanogaster

Alignment Length:	195	Identity:	44/195 - (22%)
Similarity:	82/195 - (42%)	Gaps:	20/195 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 CVAREDA-----MKCIVTALADPNTFLLDPLLSLKPVRFLEG--DLIH-DLLSIFVSEKLPAYVQ 255
            ||..:.:     :..|..||..||.|:...||:...|..|:.  |..| :.|::|.   ...|.:
  Fly    24 CVLAKSSTGAALLDVIRQALEAPNVFVFGELLAEPSVLQLKDGPDSKHFETLNLFA---YGTYKE 85

  Fly   256 FYEDHREFVNSQGLNHEQNMKKMRLLTFMQLAESSPEMTFETLTKELQI-NEDEVEPFVIEVLKT 319
            :.....:|:...    ....||::.||.:.||..:..:.:..|..||:| |...:|..:||.:..
  Fly    86 YRAQPEKFIELT----PAMQKKLQHLTIVSLAIKAKSIPYALLLSELEIDNVRHLEDIIIEAIYA 146

  Fly   320 KLVRARLDQANQKVHISSTMHRTFGAPQWEQLRDLLQAWKENLSTVREGLTSVSSAQLDLARSQK 384
            .::..:|.|..:.:.:.....|........|:.:.||||..:..:|    ::....|:..|.::|
  Fly   147 DIIHGKLFQNTRILEVDYAQGRDIPPGYTGQIVETLQAWVNSCDSV----SNCIEMQIKYANAEK 207

Fly 385 384
Fly 208 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
eIF3m	NP_001286407.1	PCI	236..336	CDD:396121	22/101 (22%)
eIF3m	NP_001286407.1	eIF3m_C_helix	341..369	CDD:407846	7/27 (26%)
CSN7	NP_610379.2	PAM	96..185	CDD:214803	20/92 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45447370
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR15350
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940