Protein Alignment eIF3m and cif-1

DIOPT Version :9

• Sequence 1: NP_001286407.1
• Gene: eIF3m / 36565
• FlyBaseID: FBgn0033902
• Length: 387
• Species: Drosophila melanogaster
• Sequence 2: NP_500618.1
• Gene: cif-1 / 177236
• WormBaseID: WBGene00019543
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 109/386 - (28%)
• Similarity: 198/386 - (51%)
• Gaps: 26/386 - (6%)

  Fly     5 PVFIDLSLDEQVQELRKYFKKLGAEISSEKSNKGVEDDLHKIIGVCDVCFKDGEPS---QIDGIL 66
            |||..:...:|:||||:|..|   ..|.:....|..:....:|.:|...  :..||   .:|.:|
 Worm     8 PVFAYIDDVKQLQELRQYLNK---HDSVKLDPNGPSETAQNMIEICSTL--NVLPSWSQDVDLVL 67

  Fly    67 NSIVSIMITIPLDRGENIVLAYCEKMTK--------APNLPLGKVCLQSLWRLFNNLDTASPLRY 123
            |||.|:::.:|.::.|.:|.::.:.:..        |.:..:....|.:|::.::|..|   ::.
 Worm    68 NSISSLIVVVPGEKCEPVVDSFIKNVAPQFYKGTGWASHAGIAVRVLSNLYKGYSNFHT---VQE 129

  Fly   124 HVYYHLVQVAKQCEQVLEVFSGVDQLKSQFANCPPSSEQMQKLYRLLH-DVTKDTNLELSSKVMI 187
            .::..||.:..:...:.|:...::.|:.:|.......|..:::.|.:| .:..|..::.::|||.
 Worm   130 KIFKALVDMCAEARLIGELECNLETLQDRFNTWKTPVEGQREILRAVHRALLVDQRVDQAAKVMT 194

  Fly   188 ELLGTYTADNACVAREDAMKCIVTALADPNTFLLDPLLSLKPVRFLE--GDLIHDLLSIFVSEKL 250
            .||||||..:|..||:|||:|:.||:.||.:|..|.|..|..|:.|:  ..|:...|.:|:|..|
 Worm   195 ALLGTYTEKDAAAARDDAMECVRTAVVDPKSFSFDHLERLSAVKALKTSDPLMFTALELFISGTL 259

  Fly   251 PAYVQFYEDHREFVNSQGLNHEQN--MKKMRLLTFMQLAESSPEMTFETLTKELQINEDE-VEPF 312
            ..|.:|...:.:|| ::.|..::.  :||:||||.|.|||...|::.:.|.|:|.|..|| :|.|
 Worm   260 KDYKEFVAKNPKFV-TEHLKVDETILLKKIRLLTLMSLAEEKNEISLDELAKQLDILADETLEEF 323

  Fly   313 VIEVLKTKLVRARLDQANQKVHISSTMHRTFGAPQWEQLRDLLQAWKENLSTVREGLTSVS 373
            ||:.::...:..::::..:.:.:||..||.||..||..|...|:....||......:..|:
 Worm   324 VIDAIQVNAISGKINEMARTLIVSSYQHRRFGTEQWVLLEKRLKVLIANLKQTHNNVHEVN 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF3m	NP_001286407.1	PCI	236..336	CDD:396121	31/102 (30%)
		eIF3m_C_helix	341..369	CDD:407846	9/27 (33%)
cif-1	NP_500618.1	PCI	245..347	CDD:279707	31/102 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166691
Domainoid	1	1.000	89	1.000	Domainoid score	I4981
eggNOG	1	0.900	-	-		E1_KOG2753
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4639
Inparanoid	1	1.050	150	1.000	Inparanoid score	I2972
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54703
OrthoDB	1	1.010	-	-		D353768at33208
OrthoFinder	1	1.000	-	-		FOG0005091
OrthoInspector	1	1.000	-	-		oto18422
orthoMCL	1	0.900	-	-		OOG6_103094
Panther	1	1.100	-	-	LDO	PTHR15350
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2512
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840