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Protein Alignment O-fut1 and POFUT1

DIOPT Version :9

Sequence 1:	NP_001286406.1	Gene:	O-fut1 / 36564	FlyBaseID:	FBgn0033901	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_056167.1	Gene:	POFUT1 / 23509	HGNCID:	14988	Length:	388	Species:	Homo sapiens

Alignment Length:	392	Identity:	172/392 - (43%)
Similarity:	237/392 - (60%)	Gaps:	27/392 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VNLILLLISSTCAQLGG-DPNGYLTYCPCMGRFGNQADHFLGSLAFAKALNRTLILPPWVEYR-- 72
            |:.:|||:.......|. ||.|||.|||||||||||||||||||||||.|||||.:|||:||:
Human    12 VSFLLLLLPLPGMPAGSWDPAGYLLYCPCMGRFGNQADHFLGSLAFAKLLNRTLAVPPWIEYQHH 76

  Fly    73 RGELRSRQVPFNTYFEVEPLKEYHRVITMADFMWHLADDIWPESERVSFCYKERYSLQQEKNDPD 137
            :....:..|.:..||::|||:.|||||::.|||..||...||..:||::|::     ...:..||
Human    77 KPPFTNLHVSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPEKRVAYCFE-----VAAQRSPD 136

  Fly   138 KPNCHAKDGNPFGPFWDTFHIDFVRSEFYAPLHFDVHHSNEAAKWQTKYPAESYPVLAFTGAPAS 202
            |..|..|:|||||||||.||:.|.:||.:..:.|...:..:   |..::..:.:||||..||||.
Human   137 KKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQ---WSQRFSPKEHPVLALPGAPAQ 198

  Fly   203 FPVQLENCKLQRYLQWSQRYREASKDFIREQLPRGAFLGIHLRNGIDWVRACEHVKD---SQHLF 264
            |||..|:..||:|:.||....:..:..|...|.| .::|||||.|.||..||..:||   ..|..
Human   199 FPVLEEHRPLQKYMVWSDEMVKTGEAQIHAHLVR-PYVGIHLRIGSDWKNACAMLKDGTAGSHFM 262

  Fly   265 ASPQCLGYKNERGA-LYPELCMPSKEAIIRQLKRTIKNVRQTQPDNEIKSVFVASDSNHMIGELN 328
            |||||:||.....| |...:|:|..:.|.|.:|..::::       :.:||:||:||...:.||.
Human   263 ASPQCVGYSRSTAAPLTMTMCLPDLKEIQRAVKLWVRSL-------DAQSVYVATDSESYVPELQ 320

  Fly   329 TALSRMGISVHKLPEDDPYLDLAILGQSNHFIGNCISSYSAFEKRERDVHGFPSYFWGF---PKE 390
             .|.:..:.|..|..:...:||.||||::||||||:||::||.|||||:.|.||.|:|.   ||.
Human   321 -QLFKGKVKVVSLKPEVAQVDLYILGQADHFIGNCVSSFTAFVKRERDLQGRPSSFFGMDRPPKL 384

  Fly   391 KD 392
            :|
Human   385 RD 386

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.