DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment O-fut1 and pfut-1

DIOPT Version :9

Sequence 1:	NP_001286406.1	Gene:	O-fut1 / 36564	FlyBaseID:	FBgn0033901	Length:	402	Species:	Drosophila melanogaster
Sequence 2:	NP_741744.2	Gene:	pfut-1 / 180607	WormBaseID:	WBGene00015793	Length:	389	Species:	Caenorhabditis elegans

Alignment Length:	402	Identity:	171/402 - (42%)
Similarity:	245/402 - (60%)	Gaps:	29/402 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 VNLILLLIS--STCAQLGG-----DPNGYLTYCPCMGRFGNQADHFLGSLAFAKALNRTLILPPW 68
            |:.:|.|.|  |.|:....     |||||:.:||||||||||.|.|||.|||||||:|||:||.:
Worm     3 VSKVLTLASFISVCSYSEAKSNETDPNGYIVFCPCMGRFGNQVDQFLGVLAFAKALDRTLVLPNF 67

  Fly    69 VEYRRGELRSRQVPFNTYFEVEPLKEYHRVITMADFMWHLADDIWPESERVSFCYKERYSLQQEK 133
            :|::..|  ::.:||...|:|..:.:|.||:||.:|...:...:||..:|.:||:..|.::..:.
Worm    68 IEFKHPE--TKMIPFEFLFQVGTVAKYTRVVTMQEFTKKIMPTVWPPEKRKAFCWTPRQAIYDKS 130

  Fly   134 NDPDKPNCHAKDGNPFGPFWDTFHIDFVRSEFYA--PLHFDVHHSNEAAKWQTKYPAESYPVLAF 196
            .:   |.||:|:||||||:||...:.||..|::.  |..||::......||..|:|:|.||||||
Worm   131 AE---PGCHSKEGNPFGPYWDQIDVSFVGDEYFGDIPGGFDLNQMGSRKKWLEKFPSEEYPVLAF 192

  Fly   197 TGAPASFPVQLENCKLQRYLQWSQRYREASKDFIREQLPRGAFLGIHLRNGIDWVRACEHVKDSQ 261
            :.|||.||.:.:...:|:||:||.|..|.:|.||...|.: .|:.:||||..||||.|||:..:.
Worm   193 SSAPAPFPSKGKVWSIQKYLRWSSRITEQAKKFISANLAK-PFVAVHLRNDADWVRVCEHIDTTT 256

  Fly   262 H--LFASPQCLGYKNERGALYPELCMPSKEAIIRQLKRTIKNVRQTQPDNEIKSVFVASDSNHMI 324
            :  ||||.||||..:..|.|..|:|.|||:.|:.|:...:.::       ..||||||||.:|||
Worm   257 NRPLFASEQCLGEGHHLGTLTKEICSPSKQQILEQIVEKVGSI-------GAKSVFVASDKDHMI 314

  Fly   325 GELNTALSRMGISVHKLPEDDPYLDLAILGQSNHFIGNCISSYSAFEKRERDVHG---FPSYFWG 386
            .|:|.||....|..|:...||.|..|||:|:::.|:|||:|::|...|||||..|   .||.|:|
Worm   315 DEINEALKPYEIEAHRQEPDDMYTSLAIMGRADLFVGNCVSTFSHIVKRERDHAGQSPRPSAFFG 379

  Fly   387 FPKEKDRKHTNV 398
            ....|  :|.::
Worm   380 IRAVK--RHIDL 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
O-fut1	NP_001286406.1	O-FucT-1	28..388	CDD:211388	163/366 (45%)
O-fut1	NP_001286406.1	O-FucT	38..381	CDD:287252	152/349 (44%)
pfut-1	NP_741744.2	O-FucT-1	27..381	CDD:211388	163/366 (45%)
pfut-1	NP_741744.2	O-FucT	37..374	CDD:287252	152/349 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156148
Domainoid	1	1.000	315	1.000	Domainoid score	I695
eggNOG	1	0.900	-	-		E1_KOG3849
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9104
Inparanoid	1	1.050	327	1.000	Inparanoid score	I1458
Isobase	1	0.950	-	0	Normalized mean entropy	S3907
OMA	1	1.010	-	-		QHG52390
OrthoDB	1	1.010	-	-		D1127619at2759
OrthoFinder	1	1.000	-	-		FOG0006613
OrthoInspector	1	1.000	-	-		oto17534
orthoMCL	1	0.900	-	-		OOG6_106532
Panther	1	1.100	-	-	LDO	PTHR21420
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2700
SonicParanoid	1	1.000	-	-		X5612
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750