Protein Alignment CysRS-m and Cars2

DIOPT Version :10

• Sequence 1: NP_610930.1
• Gene: CysRS-m / 36563
• FlyBaseID: FBgn0033900
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_011240384.1
• Gene: Cars2 / 71941
• MGIID: 1919191
• Length: 619
• Species: Mus musculus
• Alignment Length: 588
• Identity: 213/588 - (36%)
• Similarity: 301/588 - (51%)
• Gaps: 96/588 - (16%)

  Fly    38 WRKPIGQHTGINIYNHGLRQKVPLILRNPQMVTWYTCGPTVYDSAHLGHASTYVKVDILQRILRD 102
            |::|.||.||:.::|....:|.|||:.....|:||:|||||||.||||||.:||:.||::|||..
Mouse    27 WQRPQGQDTGVQVHNSLTGRKEPLIVARSDAVSWYSCGPTVYDHAHLGHACSYVRFDIIRRILTR 91

  Fly   103 YFKINLVTAMNITDVDDKIIKRAQLAGLDWQKMARAYEAEFRQDMLRLNVQAPDVRSHVTTTMPV 167
            .|..|:|.||:||||||||||||....:....:|..:|.||:|||..|.|..|.|...||..:|.
Mouse    92 VFGCNVVMAMSITDVDDKIIKRANEMNVTPASLASLFEEEFKQDMAALKVLPPTVYLRVTENIPQ 156

  Fly   168 IIQFIQQLIDGKQAYVTPDNSVYFDV-SKSKNYGKLQNL---GLSEDKLDPIKRNTADFALWKAR 228
            ||.||:.:|....||.|...|||||: ::...||||.|.   ..:|...|..||:::|||||||.
Mouse   157 IIAFIEGIIAHGHAYSTATGSVYFDLHARGDKYGKLVNTVPSATAEPAGDSDKRHSSDFALWKAA 221

  Fly   229 KSGSEPTWAAPWGGEGRPGWHIECSAIAGLFFGRQLDIHAGGLDLRFPHHENEEAQCCARYKTDQ 293
            |. .|..||:|| |:||||||||||.:|...||..||||.||:||.|||||||.||....::..|
Mouse   222 KP-QEVFWASPW-GDGRPGWHIECSTMASEVFGSHLDIHTGGIDLAFPHHENEIAQSEVFHQCQQ 284

  Fly   294 WVNYWVHTGQLHMVGDREKMSKSLGNTISV----------------------------------- 323
            |.||::|:|.||:.|..|||||||.|.|::
Mouse   285 WGNYFLHSGHLHVKGTEEKMSKSLKNYITIKDCRLSGRSLLDSCLHCCFDSIAEPSRGPKGKQDL 349

  Fly   324 --------------------------------SELLKKYTADEFRMACLLSNYRNAMPYSDQLMV 356
                                            .:.||.::.|.||:.||.:|||:|:.|||..:|
Mouse   350 PLRCDLHGGTTDPVHILHKGLLNRVTQLPFWSKDFLKTFSPDVFRLFCLRTNYRSAIEYSDSTLV 414

  Fly   357 TARQTLQRFRNFQADLSAYTQFLKPVHLLDEGALKAQLTHTVTEFDNCLRDDFDTARAISVLIDQ 421
            .|:..|....:|..|..||.:.......::|..|..:||.|.......|.:||||.||::.::|.
Mouse   415 EAKHLLLGLASFVEDARAYVKGQLTCGPVEEDVLWERLTSTKKAVKAALANDFDTPRAVNTILDL 479

  Fly   422 MSSISRCIN--EQQVDAQEEPAYCIDLLLAAGNFINRAIVTFGLSELQDKESLQEKVSFTDHSID 484
            :...:|.:.  .::......|.    :..|..:::.:...|.|:| |.:::.    ||....::.
Mouse   480 VHHANRQLRAVSKEASGPRSPT----VFGAIISYVEQFFETVGIS-LANRQC----VSGDSSTVT 535

  Fly   485 PNLLVNDVINVRGRMRERA-----TSGNVKNPQ------LLAACDELRSLLQQHGIQVRDH-KQG 537
            ...:|::::..|.::|:.|     .:|..:..|      ||.|||.||..|..|||.|:|. ...
Mouse   536 LRCVVDELVRFRLKVRQYALDTPGAAGEARKRQLQERQPLLEACDTLRQDLVTHGINVKDRGSAA 600

  Fly   538 SSW 540
            |:|
Mouse   601 STW 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS-m	NP_610930.1	CysS	48..543	CDD:439985	207/578 (36%)
Cars2	XP_011240384.1	PTZ00399	27..614	CDD:240402	213/588 (36%)