Protein Alignment CysRS-m and cars1

DIOPT Version :10

• Sequence 1: NP_610930.1
• Gene: CysRS-m / 36563
• FlyBaseID: FBgn0033900
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001112372.1
• Gene: cars1 / 368284
• ZFINID: ZDB-GENE-030328-29
• Length: 824
• Species: Danio rerio
• Alignment Length: 711
• Identity: 209/711 - (29%)
• Similarity: 313/711 - (44%)
• Gaps: 186/711 - (26%)

  Fly    18 ALICR----RNI----------------SEEAPKQDSPFK-----WRKPIGQH-TGINIYNHGLR 56
            ||:||    |::                ::::|:..:..|     |..|.|.. :.:.:||...|
Zfish    51 ALLCRPPPERHVHALRWYKHIAFLKPQANDQSPECSTKGKRVQPPWSPPEGTDISKLRLYNSLTR 115

  Fly    57 QKVPLILRNPQMVTWYTCGPTVYDSAHLGHASTYVKVDILQRILRDYFKINLVTAMNITDVDDKI 121
            .|...:.:....|.||.|||||||::|:|||.:|:..|||:|||::|||.::...|||||:||||
Zfish   116 TKEVFVPQKGNRVLWYCCGPTVYDASHMGHARSYISFDILRRILKNYFKYDVFYCMNITDIDDKI 180

  Fly   122 IKRAQ--------------------------------------------LAGLD----------- 131
            ||||:                                            |..||
Zfish   181 IKRARQNYLLEQYREKKPSAAQILQDVLTARTPFKAKLAETTDPDKKQMLERLDSAVDAALGPLQ 245

  Fly   132 -----------WQKMARA---------------------------------YEAEFRQDMLRLNV 152
                       .||.|:.                                 :|.|:.:||..|||
Zfish   246 VAVQSKAAQDSIQKQAQVLLEEAKDLLSDWLDSQFGSQVTENSIFSLLPKYWEGEYHKDMEALNV 310

  Fly   153 QAPDVRSHVTTTMPVIIQFIQQLIDGKQAYVTPDNSVYFDVSK-----SKNYGKL---------- 202
            ..|||.:.|:..:|.|::|:::::|....|.: :.|||||.:|     :.:|.||
Zfish   311 LPPDVLTRVSEYVPEIVEFVKKIVDNGYGYES-NGSVYFDTAKFDSCPAHSYAKLVPEAVGDQKA 374

  Fly   203 -----QNLGLSEDKLDPIKRNTADFALWKARKSGSEPTWAAPWGGEGRPGWHIECSAIAGLFFGR 262
                 .:|.:|.|:|.. ||:..|||||||.|.| ||:|.:|| |.|||||||||||:||...|.
Zfish   375 LQEGEGDLSISADRLSE-KRSQNDFALWKASKPG-EPSWDSPW-GMGRPGWHIECSAMAGSILGE 436

  Fly   263 QLDIHAGGLDLRFPHHENEEAQCCARYKTDQWVNYWVHTGQLHMVGDREKMSKSLGNTISVSELL 327
            .:|||.||.|||||||:||.||..|.::.|.||.|::|||.|.:.|.  ||||||.|.|::.:.|
Zfish   437 SMDIHGGGFDLRFPHHDNELAQSEAYFENDYWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDAL 499

  Fly   328 KKYTADEFRMACLLSNYRNAMPYSDQLMVTARQTLQRFRNFQADLSAYTQFLKPVHL-------- 384
            .|:||.:.|:|.|:.::::.:.||:..|.:|.| .:||.| :..|:.......|..:
Zfish   500 AKHTARQLRLAFLMHSWKDTLDYSNNTMESAIQ-YERFIN-EFFLNVKDILRSPTDITGQYEKWE 562

  Fly   385 LDEGALKAQLTHTVTEFDNCLRDDFDTARAIS---VLIDQMSSISRCINEQQVDAQEEPAYCIDL 446
            .:|..|........|.....|.|:.||..|:.   .|:.|.::........::.....      |
Zfish   563 AEEIELNKCFYDKKTSVHGALCDNIDTRSALEEMRALVGQSNTYMAARRSAKLPPNRM------L 621

  Fly   447 LLAAGNFINRAIVTFGLSELQDKESLQEKVSFTDHSIDPNLLVNDVINVRGRMRE--RATSGNVK 509
            |.:...::...:.|||  .::..:.:...|.....|.|....|...::|....||  |..:...|
Zfish   622 LQSIALYLTDMLKTFG--AIEGTDPIGFPVGGNGQSADLESTVMPYLSVLSDFREDVRKIAREKK 684

  Fly   510 NPQLLAACDELR-SLLQQHGIQVRDHKQGSSWVFAVSCEK-----------QDDKSKSSAE 558
            ..:||..||:|| ..|.:.|:::.|.....:.|..|..|.           :|||.|...|
Zfish   685 VTELLQLCDQLRDDTLPELGVRLEDRDGLPTSVKLVDKETLLKEKEEKKKLKDDKRKKKEE 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS-m	NP_610930.1	CysS	48..543	CDD:439985	192/627 (31%)
cars1	NP_001112372.1	GST_C_CysRS_N	2..74	CDD:198343	5/22 (23%)
		PTZ00399	85..822	CDD:240402	203/677 (30%)