Protein Alignment CysRS-m and Cars1

DIOPT Version :10

• Sequence 1: NP_610930.1
• Gene: CysRS-m / 36563
• FlyBaseID: FBgn0033900
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: NP_001425105.1
• Gene: Cars1 / 293638
• RGDID: 1310747
• Length: 831
• Species: Rattus norvegicus
• Alignment Length: 676
• Identity: 204/676 - (30%)
• Similarity: 310/676 - (45%)
• Gaps: 157/676 - (23%)

  Fly    21 CRRNISEEAPKQDSPFKWRKPIG-QHTGINIYNHGLRQKVPLILRNPQMVTWYTCGPTVYDSAHL 84
            ||...|:....|.   :|..|.| :...:.:||...|.|...|.::.:.||||.|||||||::|:
  Rat    87 CRLQASKGRRVQP---QWSPPAGTEPCRLRLYNSLTRNKDVFIPQDGKKVTWYCCGPTVYDASHM 148

  Fly    85 GHASTYVKVDILQRILRDYFKINLVTAMNITDVDDKIIKRAQLAGL------------------- 130
            |||.:|:..|||:|:|||||:.::...|||||:|||||:||:...|
  Rat   149 GHARSYISFDILRRVLRDYFQYDVFYCMNITDIDDKIIRRARQNYLFEQYREQKPSAAQLLKDVG 213

  Fly   131 ----------------------------------------------------------------- 130
                                                                             
  Rat   214 DAMKPFSVKLSETTDPDKRQMLERIQNSVKLATEPLEQAVHSNPSGEEVDSRVQVLLEEAKDLLS 278

  Fly   131 DW---------------QKMARAYEAEFRQDMLRLNVQAPDVRSHVTTTMPVIIQFIQQLIDGKQ 180
            ||               .|:.:.:|.||.:||..|||..|||.:.|:..:|.|:.|:|:::|...
  Rat   279 DWLDSTGGSEVTDNSIFSKLPKFWEEEFHKDMEALNVLPPDVLTRVSEYVPEIVNFVQKIVDNGY 343

  Fly   181 AYVTPDNSVYFDVSK-----SKNYGKL---------------QNLGLSEDKLDPIKRNTADFALW 225
            .|.: :.|||||.:|     ..:||||               .:|.:|.|:|.. ||:..|||||
  Rat   344 GYAS-NGSVYFDTAKFAASEKHSYGKLVPEAVGDQKALQEGEGDLSISADRLSE-KRSPNDFALW 406

  Fly   226 KARKSGSEPTWAAPWGGEGRPGWHIECSAIAGLFFGRQLDIHAGGLDLRFPHHENEEAQCCARYK 290
            ||.|.| ||:|..|| |:|||||||||||:||...|..:|||.||.|||||||:||.||..|.::
  Rat   407 KASKPG-EPSWPCPW-GKGRPGWHIECSAMAGSLLGASMDIHGGGFDLRFPHHDNELAQSEAYFE 469

  Fly   291 TDQWVNYWVHTGQLHMVGDREKMSKSLGNTISVSELLKKYTADEFRMACLLSNYRNAMPYSDQLM 355
            .|.||.|::|||.|.:.|.  ||||||.|.|::.:.|||::|.:.|:|.|:.::::.:.||...|
  Rat   470 NDCWVRYFLHTGHLTIAGC--KMSKSLKNFITIKDALKKHSARQLRLAFLMHSWKDTLDYSSNTM 532

  Fly   356 VTARQTLQRFRN---------FQADLSAYTQFLKPVHLLDEGALKAQLTHTVTEFDNCLRDDFDT 411
            .:|.| .::|.|         .:|.:....||.|  ...:|..|........|.....|.|:.||
  Rat   533 ESALQ-YEKFMNEFFLNVKDILRAPVDITGQFEK--WEAEEVELNKNFYDKKTAVHEALCDNIDT 594

  Fly   412 ARAISVLIDQMSSISRC--INEQQVDAQEEPAYCIDLLLAAGNFINRAIVTFGLSELQDKESLQE 474
            .   :|:.:..:.:|:|  ....:..|:..|...  ||.....::...:..||  .::::..|..
  Rat   595 R---TVMEEMRALVSQCNLYMAARKAARRRPNRA--LLENIAMYLTHMLKIFG--AIEEENPLGF 652

  Fly   475 KVSFTDHSIDPNLLVNDVINVRGRMRE--RATSGNVKNPQLLAACDELR-SLLQQHGIQVRDHKQ 536
            .|.....:::....|...:.|....||  |..:...|..::|...|.|| .:|.:.|::..||:.
  Rat   653 PVGGPGTNLNLESTVMPYLQVLSEFREGVRKIAREKKVLEVLQLSDALRDDILPELGVRFEDHEG 717

  Fly   537 GSSWVFAVS----CEKQDDKSKSSAE 558
            ..:.|..|.    .:::::|.::..|
  Rat   718 LPTVVKLVDRDTLLKEKEEKKRAEEE 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS-m	NP_610930.1	CysS	48..543	CDD:439985	194/627 (31%)
Cars1	NP_001425105.1	None