Protein Alignment CysRS-m and CysRS

DIOPT Version :10

• Sequence 1: NP_610930.1
• Gene: CysRS-m / 36563
• FlyBaseID: FBgn0033900
• Length: 558
• Species: Drosophila melanogaster
• Sequence 2: XP_320253.2
• Gene: CysRS / 1280406
• VectorBaseID: AGAMI1_008993
• Length: 743
• Species: Anopheles gambiae
• Alignment Length: 682
• Identity: 204/682 - (29%)
• Similarity: 315/682 - (46%)
• Gaps: 179/682 - (26%)

  Fly    28 EAPKQDSPFKWRKPIGQHTGINIYNHGLRQKVPLILRNPQMVTWYTCGPTVYDSAHLGHASTYVK 92
            :||::       ||..:   :.:||...|:|...:.|:.:.|.||:|||||||::|:|||.:|:.
Mosquito    10 QAPEE-------KPAPK---LYLYNSLTRRKELFVPRDGRNVHWYSCGPTVYDASHMGHARSYIS 64

  Fly    93 VDILQRILRDYFKINLVTAMNITDVDDKIIKRAQ------------------------------- 126
            .|||:|:|.|||..|::..|||||:||||||||:
Mosquito    65 FDILRRVLSDYFGYNVLYVMNITDIDDKIIKRARQNHLYERYLQQSKDMPLERLLDDSKEVMATF 129

  Fly   127 -----------------------LAGLD------------------------------------- 131
                                   .|.:|
Mosquito   130 RENLARTTDADKKTMMDRMLEKLTAAVDNLSLAVKEGDEGRIQQAQDQFLQDSKDPLADLLDSKQ 194

  Fly   132 ---------WQKMARAYEAEFRQDMLRLNVQAPDVRSHVTTTMPVIIQFIQQLIDGKQAYVTPDN 187
                     ::.:.|.:|..|.:||..|||..|||.:.|:..:|.|:.:|:::|....|| ..:.
Mosquito   195 GSSVTENAIFETLPRYWEDAFHKDMAALNVLQPDVLTRVSEYVPQIVTYIEKIIANGLAY-EANG 258

  Fly   188 SVYFDVS-----KSKNYGKL---------------QNLGLSEDKLDPIKRNTADFALWKARKSGS 232
            ||||||:     :..:|.||               .:|.:..|:|.. ||:..||||||:.|:|
Mosquito   259 SVYFDVAGFDRREQHHYAKLVPEAYGDAKQLQEGEGDLSIGADRLTE-KRSANDFALWKSSKAG- 321

  Fly   233 EPTWAAPWGGEGRPGWHIECSAIAGLFFGRQLDIHAGGLDLRFPHHENEEAQCCARYKTDQWVNY 297
            ||.|.:|| |.|||||||||||:|....|..||||.||:||:||||:||.||..|...:.:||.|
Mosquito   322 EPWWDSPW-GRGRPGWHIECSAMASDICGDYLDIHTGGVDLKFPHHDNELAQSEAHDGSAEWVKY 385

  Fly   298 WVHTGQLHMVGDREKMSKSLGNTISVSELLKKYTADEFRMACLLSNYRNAMPYSDQLMVTARQTL 362
            ::|||.|.:.|.  ||||||.|.:::.::|:|:||.:.|:|.||.::::.:.|||..|..|.| .
Mosquito   386 FLHTGHLTIAGC--KMSKSLKNFVTIQQVLEKHTATQLRLAFLLHSWKDTLDYSDNTMEMAVQ-Y 447

  Fly   363 QRFRN----FQADLSAYTQF---------LKPVHLLDEGALKAQLTHTVTEFDNCLRDDFDTARA 414
            :||.|    ...||:.:.|.         .:||    |..|:.:...........|.|:.||..|
Mosquito   448 ERFLNEFFLNVKDLTRHVQTGPARDAFDRWRPV----EAELERKFADARAAIHEALCDNVDTRTA 508

  Fly   415 ISVLIDQMSSISRCINEQQ------VDAQEEPAYCIDLLLAAGNFIN-RAIVTFGLS--ELQDKE 470
            :.|:...:|:.:..|.|.:      :..:...|||.|||...|.... |..:.|.:|  ...|..
Mosquito   509 LDVMRGLVSACNVYIKEHRSAGFNALLLRRVAAYCTDLLHIFGAISGPRGGIGFPISAGAAGDGT 573

  Fly   471 SLQEKVSFTDHSIDPNLLVNDVINVRGRMRERATSGNVKNPQLLAACDELR-SLLQQHGIQVRDH 534
            .:...:   :.::.|.|  ..:...|..:||:|.  .:|..::|..||:|| .:|...|:::.|.
Mosquito   574 GMAGDL---EQTVMPYL--QALAEFRNAVREQAR--GLKATEILQLCDQLRDDVLPGLGVRLEDR 631

  Fly   535 KQGSSWVFAVSCE--------KQDDKSKSSAE 558
            :...|.:..|..|        |:.::::.:||
Mosquito   632 EGAPSALKLVPAEVLLREREAKRAEENRKAAE 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CysRS-m	NP_610930.1	CysS	48..543	CDD:439985	195/637 (31%)
CysRS	XP_320253.2	PTZ00399	6..743	CDD:240402	204/682 (30%)