Protein Alignment pea and PRP16

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_013012.3
• Gene: PRP16 / 853961
• SGDID: S000001794
• Length: 1071
• Species: Saccharomyces cerevisiae
• Alignment Length: 955
• Identity: 382/955 - (40%)
• Similarity: 552/955 - (57%)
• Gaps: 117/955 - (12%)

  Fly   356 KEVDQDSGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPE 420
            |.:|:...|.|...|      .:::|.:|      ::......|:....|...:|..|  :....
Yeast   122 KRIDKLKAKQLRQYS------PTVKDPSP------NSEQQTQNGHAETKDYEPTRSEV--VEEDR 172

  Fly   421 RW-----EIKQMISSGVLDRSEMPDFDEETGLLPK----DEDDEADIEIEI--------VEEEPP 468
            .|     :...::...:   ||:|   ||..|||.    |.||.....:::        :|..||
Yeast   173 EWYDNDDDYGNLVPEPL---SELP---EEAKLLPVIRNIDNDDALRNTVQLYPIPLKQRMEWIPP 231

  Fly   469 FLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALS--------------KERREQKMLQ-REQE 518
            |||..  ||.:..|..|:   .||:::.:...||||              ..:|..|::. |...
Yeast   232 FLSKF--ALENKVPTSII---IGSISETSSQVSALSMVNPFRNPDSEFSANAKRGSKLVALRRIN 291

  Fly   519 IEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLT----- 578
            :|.:..|.:...:......|...|..|.:                  .|..|..|..|.|
Yeast   292 MEHIQQSRDNTTVLNTAMGEVLGLENNNK------------------AKDKSNQKICDDTALFTP 338

  Fly   579 ----LVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGF-TARGK-IGCT 637
                :...::.||:::.|..|:..:.:||::::|||||||||||:.|||.|.|: ..||| |..|
Yeast   339 SKDDIKHTKEQLPVFRCRSQLLSLIRENQVVVIIGETGSGKTTQLAQYLYEEGYANDRGKSIVVT 403

  Fly   638 QPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPE-TIIKYMTDGMLLRECLMEAELKSYS 701
            |||||||:|||||||.|....||:||||:|||||.|..| |.:|::|||:||||.|::..|..||
Yeast   404 QPRRVAAISVAKRVAMEMQVPLGKEVGYSIRFEDVTDSECTKLKFVTDGILLRETLLDDTLDKYS 468

  Fly   702 VIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVE 766
            .:::||||||:::||:|.|..|..:.:|.:||||:||||::|.|||.:|..||.||||||||||:
Yeast   469 CVIIDEAHERSLNTDILLGFFKILLARRRDLKLIITSATMNAKKFSAFFGNAPQFTIPGRTFPVQ 533

  Fly   767 VLYTKEPETDYLDASLITVMQIHLRE--PPGDILLFLTGQEEIDTACEILYERM-----KSLG-- 822
            .:||..|..||::|::...::|||..  ..||||:|:||||:|:|..:.|.|:.     |..|
Yeast   534 TIYTSNPVQDYVEAAVSQAVKIHLANDCSSGDILIFMTGQEDIETTFDTLQEKFLQVYSKKFGTA 598

  Fly   823 --PDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKV 885
              .::.::.|||:|||||:::|.:||.......||::||||||||||||.||.||:|.|:.|.||
Yeast   599 NFEEINDIEILPIYSALPADLQFKIFQDLHGTKRKIIIATNIAETSLTIKGIRYVIDCGYSKLKV 663

  Fly   886 YNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTV 950
            ||.|.|:||||:||||:|.|.||:||||||.||..||||||..::::|....:||||||||:.|:
Yeast   664 YNPKIGLDSLVITPISKANADQRSGRAGRTAPGTAYRLYTEDTFKEDMYLQTIPEIQRTNLSNTL 728

  Fly   951 LQLKTMGIND-LLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKML 1014
            |.||::.:.| |..|.|:|.||:::.:.:|.:|..:.|:|..|.||.||.:||:|||:|:|||:|
Yeast   729 LLLKSLDVTDELSKFPFIDKPPLQTFLSSLYELWFIGAIDTSGQLTPLGLQMAKFPLQPSLSKIL 793

  Fly  1015 IMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFS 1079
            :::|...||||:|||||||||..||||||::|..||..:.||..|:.||||||.|:..|:.|.||
Yeast   794 LIAVRNGCSDEMLTIVSMLSVPQVFYRPKERQKEADIARNKFFIAKSDHLTLLNVFEQWRANNFS 858

  Fly  1080 NAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEG 1144
            :.||.::|||.::|.|::|:|.|||.|:...|:.|:|:||:...|:|.|||||...|||......
Yeast   859 SHWCNKHFVQYKSLVRARDIRDQLLTILKSQKIPVISSGKDWDIIKKCICSGFAHQAAKITGLRN 923

  Fly  1145 YRTLVDSQVVYIHPSSAL--FNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDP 1207
            |..|.....|.:||:|||  ....|.:|:||||:.|:|||:..||::||.||:|:....:
Yeast   924 YVHLKTGVSVQLHPTSALHGLGDLPPYVVYHELLMTSKEYICCVTSVDPFWLMEYGGLLY----- 983

  Fly  1208 TKLSKFKKNQ----------RLEPLYNKYEEPNAWRISRVRRRRN 1242
             .:.:.|.:|          ..|...:|.|:.....|.|.:..|:
Yeast   984 -DIKRIKNDQEATTTGLFGEHYEHTLDKVEDDIDINIRRCKDMRD 1027

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	2/6 (33%)
		HrpA	578..>1203	CDD:441249	323/650 (50%)
PRP16	NP_013012.3	HrpA	348..>980	CDD:441249	322/631 (51%)