Protein Alignment pea and DHR2

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_012845.1
• Gene: DHR2 / 853784
• SGDID: S000001561
• Length: 735
• Species: Saccharomyces cerevisiae
• Alignment Length: 658
• Identity: 270/658 - (41%)
• Similarity: 408/658 - (62%)
• Gaps: 33/658 - (5%)

  Fly   568 KSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTAR- 631
            ||...:.:|  |::.|::||:|:.:.:::..:..|.:.::||||||||:|||.|::.|..:..:
Yeast    65 KSLKSRASD--LLKMRETLPVYQHKREIMSYIESNPVTVLIGETGSGKSTQIPQFVLEKLYDTKK 127

  Fly   632 -GKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEA 695
             |.|..||||||||:::|.|||:|:||:||::|||::||::.|:..|.:||:||||||||.:|.:
Yeast   128 HGSIAVTQPRRVAAINLATRVAQEHGCKLGEQVGYSVRFDNTTTTRTRLKYLTDGMLLRELMMNS 192

  Fly   696 ELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQ-KRPELKLIVTSATLDAVKFSQYFFKAPIFTIP 759
            :|:.||||::|||||||:.||::.|.||:.:| .||:|::||.||||.|.|||::|..|||..:.
Yeast   193 DLREYSVIVIDEAHERTVLTDLILGFLKSLIQGPRPDLRIIVMSATLQAEKFSEFFNNAPILFVE 257

  Fly   760 GRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPD 824
            ||.|.|:..|.|.|..|.:||.:...:||:..|..||||.||.||||||.|..|:.:..|.:..:
Yeast   258 GRKFDVKQYYLKAPTDDIVDAVIRCCIQINQGEELGDILCFLPGQEEIDKAVTIMEKIAKYVSDE 322

  Fly   825 --VPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYN 887
              ||.::..|:|:|||:..|:.:|.|.....||||.:|||||||:||.|:.:|||.|..|.||:.
Yeast   323 APVPLIVPYPLYAALPAVQQSLVFAPIKGFKRKVVFSTNIAETSVTISGVKFVVDSGLRKVKVWR 387

  Fly   888 SKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLP-TPVPEIQRTNLATTVL 951
            .:.|:.:|:..|||||:|.||:|||||...||::|||.|..|  ..|| ...|||.|:::.:.||
Yeast   388 HQLGLATLLTVPISQASAMQRSGRAGRESEGKSFRLYCESDY--VKLPKQSEPEIARSDVTSPVL 450

  Fly   952 QLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIM 1016
            .||..|::|||::.:.:.|..|::||.|::|:.|.|||..|.:|:.|::||..||:|:||.:||.
Yeast   451 MLKRYGVDDLLNWTWFENPGKEAIVMGLQELYELGALDTRGKITKRGQQMALLPLQPHLSSVLIK 515

  Fly  1017 SVALQCSDEILTIVSMLSVQNVFYR--PKDKQALADQKKAKFNQAE--GDHLTL-----LAVYNS 1072
            :..:.|..:::.|||.|||:|:...  |:::..:.:::.:..|..:  ||.:.|     :..|..
Yeast   516 ASEVGCLSQVIDIVSCLSVENLLLNPSPEERDEVNERRLSLCNAGKRYGDLIMLKELFDIYFYEL 580

  Fly  1073 WKNNKFS---NAWCYENFVQIRTLKRSQDVRKQL----------LGIMDRHKLDVVSAGKNSVRI 1124
            .|:...|   |.||....:.||..|....||.||          :...|.....:...|:...:|
Yeast   581 GKSQDASSERNDWCKGLCISIRGFKNVIRVRDQLRVYCKRLFSSISEEDEESKKIGEDGELISKI 645

  Fly  1125 QKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALF-NRQPEWVIYHELVQTTKEYMREVTT 1188
            .|...:||.:|.|...|...|||:...:.:.|||||.|| |:....::|.|.|.|||.|.|.|:.
Yeast   646 LKCFLTGFIKNTAIGMPDRSYRTVSTGEPISIHPSSMLFMNKSCPGIMYTEYVFTTKGYARNVSR 710

  Fly  1189 IDPKWLVE 1196
            |:..||.|
Yeast   711 IELSWLQE 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	267/648 (41%)
DHR2	NP_012845.1	HrpA	79..>534	CDD:441249	211/456 (46%)
		OB_NTP_bind	645..722	CDD:400182	31/74 (42%)