Protein Alignment pea and Tdrd9

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_083332.1
• Gene: Tdrd9 / 74691
• MGIID: 1921941
• Length: 1383
• Species: Mus musculus
• Alignment Length: 936
• Identity: 230/936 - (24%)
• Similarity: 406/936 - (43%)
• Gaps: 228/936 - (24%)

  Fly   439 PDFDEETGLLPKDEDDEADIEIEIVEEEP------PFLSGHGRALHDLSPVRIVKNPDGSLAQAA 497
            |.|..|.   |::|...::   |:..|:|      |        :...:|.|.......||:|.:
Mouse    30 PAFPAEA---PREEVQRSE---EVPNEDPTAQAQVP--------VKATAPARPASTSGRSLSQRS 80

  Fly   498 MMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKH 562
            .....::|.|:.:     |||            :|...:|:              ||..|
Mouse    81 SEMEYINKYRQLE-----EQE------------LDIYGQDQ--------------PPSGP----- 109

  Fly   563 VIGGKKSSFGKKTDLTLVEQR----QSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYL 623
               |.:|...|.:::..:.:.    ..|||.:.::::|..:..|.::|:.|.|||||:||:.||:
Mouse   110 ---GLRSPLAKLSNVACIPETTYKYPDLPINRCKEEVISLIESNSVVIIHGATGSGKSTQLPQYV 171

  Fly   624 GECGFTARG---KIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDG 685
            .: .:|.|.   .|..||||::.|.|:|:.:::|....||..|||.:..|...:.:|.:.|||.|
Mouse   172 LD-HYTQRSAFCNIVVTQPRKIGASSIARWISKERSWTLGGLVGYQVGLEKIATEDTRLIYMTTG 235

  Fly   686 MLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPE-LKLIVTSATLDAVKFSQY 749
            :||::.:....|..::.|.:||.||||...|.|..:::..::.... :|:::.|||::..:|:.|
Mouse   236 VLLQKIVSAKSLMEFTHIFIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATINCKQFADY 300

  Fly   750 FF--------KAPIFTIPGRTFPVEVLY---------------TKEP----ETDYLDASLITVM- 786
            |.        .|.:|.:.|:...:|..|               .:||    :...:..|||.:.
Mouse   301 FAVPVQNKMNPAYVFEVEGKPHAIEEYYLNDLGHIYHSGLPYRLEEPVITKDVYEVAVSLIQMFD 365

  Fly   787 QIHLRE-------------PPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALP 838
            .:.::|             ....:|:||.|..||:...|:|...:..      .|.:.|::|::.
Mouse   366 DLDMKESGNKTWSGAQFVSERSSVLVFLPGLGEINYMHELLTNMIHK------RLQVYPLHSSVT 424

  Fly   839 SEMQTRIF-DPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQ 902
            .|.|..:| .|.| |.||::::|||||:|:|:..:.||:|....:..|.:..|...||.::..|:
Mouse   425 LEEQNNVFLSPVP-GYRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASK 488

  Fly   903 AAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPT-PVPEIQRTNLATTVLQLKTMGIND---LLH 963
            .:..||.|||||...|..||| ..|.:.|..:|. .|||:.|..|.:|:|::|.:.:.:   ||.
Mouse   489 TSCDQRKGRAGRVSKGYCYRL-IPRDFWDSAIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLA 552

  Fly   964 FDFMDAPP----VESLVMALEQLHSLSA---LDDE----GLLTRLGRRMAEFPLEPNLSKMLIMS 1017
            ...  :||    :|..::.|:::.:|:.   .:||    |.||.|||.:|:.|:...|.|::::.
Mouse   553 TAL--SPPSLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVSQQLGKLVVLG 615

  Fly  1018 VALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFN-QAEGDHLTLLAVYNSW-------- 1073
            ....|.||.|.|.:.||::|.|..|..:.....:.|..|: .:..|.|.|:..:.:|
Mouse   616 HVFGCLDECLIIAAALSLKNFFTMPFRQHLDGYRNKVHFSGSSRSDCLALVEAFRAWQACRQRGE 680

  Fly  1074 -KNNKFSNAWCYENFVQIRTLKRSQDVRKQLLG--------------IMD-------RHKLDVVS 1116
             :..|....|...|::||:.::...::.::|..              ::|       |..|.||.
Mouse   681 LRRPKDELDWGRLNYIQIKRIREVAELYEELKNRISQFNMFVGPHHPVLDQEYPYKQRFILQVVL 745

  Fly  1117 AGKNSVRIQKAICSGFF-----------RNAAKKDPQEGYRTLVDSQVVYIH-PSSALFNRQPEW 1169
            ||        |....:|           |..|.|||:        :.||..| |        |..
Mouse   746 AG--------AFYPNYFTFGQPDEEMAVRELAGKDPK--------TTVVLKHIP--------PYG 786

  Fly  1170 VIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFS-DPT-------------KLSKFKKNQRL- 1219
            .:|::.:|:......:|.:|    :.:.|.:|..|| :||             |:|:.|.:..|
Mouse   787 FLYYKQLQSLFRQCGQVKSI----VFDGAKAFVEFSRNPTERFKTLPAVNLAVKMSQLKVSLELS 847

  Fly  1220 ----EPLYNKYEEPNAWRISRVRRRR 1241
                |.:..|.:   ...:|::|..|
Mouse   848 VHAAEEIEGKVQ---GGSVSKLRNTR 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	190/732 (26%)
Tdrd9	NP_083332.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..82		12/60 (20%)
		HrpA	132..>706	CDD:441249	164/584 (28%)
		DEAD-like_helicase_N	134..317	CDD:475120	59/183 (32%)
		DEAH box. /evidence=ECO:0000269|PubMed:28633017	256..259		2/2 (100%)
		Tudor_TDRD9	906..1006	CDD:410502