Protein Alignment pea and dhx38

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_002937626.2
• Gene: dhx38 / 734019
• XenbaseID: XB-GENE-990308
• Length: 1212
• Species: Xenopus tropicalis
• Alignment Length: 1230
• Identity: 482/1230 - (39%)
• Similarity: 694/1230 - (56%)
• Gaps: 164/1230 - (13%)

  Fly   104 PGLALPNDTYSKKEESDDDEKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKE 168
            |.|........||:.|.:::.|...|...|             :::.|:.||..:     |..:|
 Frog    15 PSLEAGGLVIKKKKSSSNEQHVFKAPAPRS-------------SLLGLDLLAAQK-----RKERE 61

  Fly   169 ------------VSSRDRHKR-RSRDRDTKRRSR-SREDRH---------------SDRRRSRSR 204
                        |||||..:| ||.||...:.|| |..|||               ::...:|:|
 Frog    62 EREQQEGEKKSKVSSRDWEERDRSPDRPNDKLSRGSHGDRHYRTPRVETPSYTGGVNEEFLARNR 126

  Fly   205 DKERRRR-----SRSRDNRRRSRSREDRDRDR-DRRHKSSSSRDHHERRRRSRSRSTERRDRRDR 263
            .:||.||     :.|:|:|:|   |::|.|:| ||..::.|.||....|...||   |....|.:
 Frog   127 QRERERREHGVYASSKDDRQR---RKERGREREDRSCRNRSERDSGSERSGRRS---EPESPRHK 185

  Fly   264 SRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEG-----------LVHI 317
            .||.|    .||.:..::.::|            :|.     ..|.:||.           ..|.
 Frog   186 PRDAS----TPSRSSWEEDDSG------------YGS-----SQRSQWESPSPAPSNRDSEKSHR 229

  Fly   318 SQL------RAE-GRVTDVTEVVTRNQTVK--VKVMSITGQKVSLSMKEVDQDSGKD-LNPLSHA 372
            |:.      |:| ||.::.:.:.|.:....  .......|....||.....|||..| :|.:|..
 Frog   230 SERESSRRERSERGRYSEESPLPTPSYKYNEWASDRRHLGSTPRLSQGRGKQDSDDDKINFMSEE 294

  Fly   373 P----EDDESLRDRN----PDGPFSSSTSMLNLQGNGMEGDEHESRKRVT-RISSP--------E 420
            .    |||:...||:    .:|...|..::.:...:.::..|.:.:|:.: |:|:.        |
 Frog   295 EQRQWEDDQRQADRDWYMMDEGFDESHNALTSTSEDYVKKREQQLQKQTSKRVSAQRRQINEDNE 359

  Fly   421 RWEIKQMISSGVLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRI 485
            |||..:|::|||:.|.|:   ||:.     :||:.|.:.:.:....||||.|.........||..
 Frog   360 RWETNRMLTSGVVQRLEV---DEDF-----EEDNAAKVHLLVHNLVPPFLDGRIVFTKQPEPVIP 416

  Fly   486 VKNPDGSLAQAAMMQSALSKERREQKMLQREQ--EIEAMPTSLN-----KNWID----PLPED-- 537
            |::....||..|...|.|.::.||||..::.|  ..|...|.|.     |..:|    |:.||
 Frog   417 VRDATSDLAIIARKGSQLVRKHREQKERKKAQHKHWELAGTKLGDIMGVKKQVDEPDKPIAEDGA 481

  Fly   538 ----ESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKA 598
                ..:..|.:||..:.|               .|.|.:|.  :|:||||.|||:.::.:|:..
 Frog   482 VDYKAEQKFADHMRERSEA---------------SSDFSRKK--SLMEQRQYLPIFAVQQELLTI 529

  Fly   599 VTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEV 663
            :.||.|:||:||||||||||:||||.|.|:|..|.|.||||||||||||||||:||....||:||
 Frog   530 IRDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIACTQPRRVAAMSVAKRVSEEMQVSLGEEV 594

  Fly   664 GYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQK 728
            ||.||||||||.:|:|||||||:||||||.||:|..||.:::||||||:::||||||||:..|.:
 Frog   595 GYAIRFEDCTSEKTLIKYMTDGILLRECLREADLDHYSAVIMDEAHERSLNTDVLFGLLREVVTR 659

  Fly   729 RPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREP 793
            |.:|||||||||:||.||:.:|...|||.||||||||::|::|.|:.||::|::...:||||...
 Frog   660 RSDLKLIVTSATMDADKFATFFGNVPIFYIPGRTFPVDILFSKTPQEDYVEAAVKQALQIHLSGA 724

  Fly   794 PGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVI 858
            .||||:|:.|||:|:...:.:.||::.| ...|.|.:||:||.|||::|.:||..||.|.||.::
 Frog   725 AGDILIFMPGQEDIEVTSDQIVERLEEL-DSAPPLAVLPIYSQLPSDLQAKIFQKAPDGVRKCIV 788

  Fly   859 ATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRL 923
            ||||||||||:|||.:|:|.|:.|.||:|.:.|||:|.:.|||||.|.||:|||||||||:.|||
 Frog   789 ATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCYRL 853

  Fly   924 YTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSAL 988
            ||:.||::|:|.|.|||||||||:..||.||::|:.|||.|.|||.||.::::.::.||..|.||
 Frog   854 YTQSAYKNELLHTTVPEIQRTNLSNVVLLLKSLGVQDLLLFHFMDPPPEDNMLNSMYQLWILGAL 918

  Fly   989 DDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKK 1053
            |:.|.||..||.|.||||:|.||||||:|..:.||.|||.:||||||..:|||||.::..:||.:
 Frog   919 DNTGALTPTGRLMVEFPLDPALSKMLIVSCDMGCSSEILIVVSMLSVPAIFYRPKGREEESDQVR 983

  Fly  1054 AKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAG 1118
            .||...|.||||.|.|:..||||.:|:.||.::|:..:.:::.::||.||..||...::.:.|.|
 Frog   984 EKFAVPESDHLTYLNVFLQWKNNNYSSGWCNQHFIHAKAMRKVREVRAQLKDIMVSQRMSLSSCG 1048

  Fly  1119 KNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNR--QPEWVIYHELVQTTKE 1181
            .:...::|.||:.:|..||:......|..:......::||:|:||..  .|::::|||||.||||
 Frog  1049 SDWDIVRKCICAAYFHQAARLKGIGEYVNVRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKE 1113

  Fly  1182 YMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKYEEPNAWRISRVRRRR 1241
            ||:.||.:|.:||.|..|.|:......| ::.:..:|.:...:..||.......::|.||
 Frog  1114 YMQCVTAVDGEWLAELGPMFYSIKHAGK-TRQENRRRAKEEVSAMEEEMMLAEEQLRARR 1172

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	17/97 (18%)
		HrpA	578..>1203	CDD:441249	337/626 (54%)
dhx38	XP_002937626.2	HrpA	517..>1175	CDD:441249	339/658 (52%)