Protein Alignment pea and dhx8

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_002932570.2
• Gene: dhx8 / 733563
• XenbaseID: XB-GENE-6087171
• Length: 1181
• Species: Xenopus tropicalis
• Alignment Length: 1247
• Identity: 862/1247 - (69%)
• Similarity: 1001/1247 - (80%)
• Gaps: 77/1247 - (6%)

  Fly     1 MDELQKLEYLSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQ 65
            |||||||||||||||:||||||||||||||||||:|.:..|..|::||:.||..|||||.|||:.
 Frog     6 MDELQKLEYLSLVSKVCTELDNHLGINDKDLAEFVISIAEKATTFETFKSALEKNGAEFTDSLIN 70

  Fly    66 NLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKVKAKPE 130
            ||.|:|..|||......|:|..:  |.:::|.:|.::||.|...::...:.....||.||.|.
 Frog    71 NLLRLIQTMRPPAKPSTSKETVI--KPKNEKEKLKELFPALCRADNPSVRTMLDPDDVKVAAD-- 131

  Fly   131 KHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRSRDRDTKRRSRSREDRH 195
                            |:.|||||.|                 :.:|.|:.:|.|:||||
 Frog   132 ----------------ALQELEALMP-----------------KDERSSKHKDKKKRSRS----- 158

  Fly   196 SDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTERRDR 260
                |||.:..:.:|:||||.  :.|:..:||.|.|.|    |..::|......|...:...:::
 Frog   159 ----RSREKGSKHKRKSRSRS--QSSKKTKDRYRSRSR----SPIKEHRNNEHHSDKYAPSWKEK 213

  Fly   261 R-DRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQLRAEG 324
            . ||        |||     ::|..|.||:||:.:|:.|||||||.|||||||||||||:||.||
 Frog   214 HVDR--------PPP-----EEPAIGDIYNGKVTSIMQFGCFVQLEGLRKRWEGLVHISELRREG 265

  Fly   325 RVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNP---LSHAPEDDESLRDRNPDG 386
            ||.:|.:||::.|.|||||:|.||.|.|||||:|:||:|:||||   .:...:.:|....||||.
 Frog   266 RVANVADVVSKGQRVKVKVLSFTGCKTSLSMKDVNQDTGEDLNPNRRRNLIGDSNEEASMRNPDR 330

  Fly   387 PFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFDEETGLLPK- 450
            |  |..|::|  ...:|.|..| |||:|:||.||:|||||||::.||.:.|.||||||||:|||
 Frog   331 P--SHLSLVN--APEIEDDTLE-RKRLTKISDPEKWEIKQMIAANVLSKEEFPDFDEETGILPKV 390

  Fly   451 -DEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQ 514
             ||:|| |:|||:||||||||.||.:...|:||::|||||||||:|||||||||:|||||.|..|
 Frog   391 DDEEDE-DLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQAAMMQSALAKERREMKQAQ 454

  Fly   515 REQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTL 579
            ||.|::::|..|||:|:||||:.:.|.:||||||:...|.::||||||..||.|:|:||||.:::
 Frog   455 REAEMDSIPMGLNKHWVDPLPDADGRQIAANMRGIGMMPNDIPEWKKHAFGGNKASYGKKTQMSI 519

  Fly   580 VEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAA 644
            ||||:|||||||::.|::||.|||||||||||||||||||||||.|.|:|.||||||||||||||
 Frog   520 VEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEAGYTTRGKIGCTQPRRVAA 584

  Fly   645 MSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAH 709
            |||||||:|||||.|||||||||||||||||||:||||||||||||||::.:|..|::|||||||
 Frog   585 MSVAKRVSEEYGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLRECLIDPDLTQYAIIMLDEAH 649

  Fly   710 ERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPE 774
            ||||||||||||||..|||||::||||||||||||||||||::||||||||||:|||:|||||||
 Frog   650 ERTIHTDVLFGLLKKTVQKRPDMKLIVTSATLDAVKFSQYFYEAPIFTIPGRTYPVEILYTKEPE 714

  Fly   775 TDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS 839
            ||||||||||||||||.|||||||:||||||||||||||||||||||||||||||||||||||||
 Frog   715 TDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS 779

  Fly   840 EMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAA 904
            |||||||||||.|||||||||||||||||||||:||||||||||||||||||:|.|||||||||.
 Frog   780 EMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQ 844

  Fly   905 AKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDA 969
            |||||||||||||||.||||||||||||||.|.||||||||||:|||.||.|||||||.||||||
 Frog   845 AKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVLSLKAMGINDLLSFDFMDA 909

  Fly   970 PPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLS 1034
            ||:|:|:.|:|||::|.||||||||||||||||||||||.|.|||||||.|.||:|:||||||||
 Frog   910 PPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLS 974

  Fly  1035 VQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDV 1099
            ||||||||||||||||||||||:|.|||||||||||||||||||||.||||||:|.|:|:|:||:
 Frog   975 VQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQARSLRRAQDI 1039

  Fly  1100 RKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFN 1164
            |||:|||||||||||||.||.:||:||||||||||||||||||||||||:|.|||||||||||||
 Frog  1040 RKQMLGIMDRHKLDVVSCGKATVRVQKAICSGFFRNAAKKDPQEGYRTLIDQQVVYIHPSSALFN 1104

  Fly  1165 RQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKYEEP 1229
            ||||||:|||||.||||||||||||||:|||||||:||:.||||||||.||.||||||||:||||
 Frog  1105 RQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLSKQKKQQRLEPLYNRYEEP 1169

  Fly  1230 NAWRISRVRRRR 1241
            |||||||..|||
 Frog  1170 NAWRISRAFRRR 1181

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	46/66 (70%)
		S1_DHX8_helicase	285..363	CDD:240189	53/77 (69%)
		HrpA	578..>1203	CDD:441249	544/624 (87%)
dhx8	XP_002932570.2	GH2-like_DHX8	12..79	CDD:409668	46/66 (70%)
		S1_DHX8_helicase	226..304	CDD:240189	53/77 (69%)
		HrpA	517..>1148	CDD:441249	547/630 (87%)