Protein Alignment pea and Dhx35

DIOPT Version :9

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_001359442.1
• Gene: Dhx35 / 71715
• MGIID: 1918965
• Length: 703
• Species: Mus musculus
• Alignment Length: 705
• Identity: 324/705 - (45%)
• Similarity: 463/705 - (65%)
• Gaps: 37/705 - (5%)

  Fly   549 MAAAPPEVPEWKKHV------IGGKKSSFGKKTDLTLV----------EQRQSLPIYKLRDDLIK 597
            |||....|..||...      |..::.|..:.:..|::          :|||.||::|||:.::.
Mouse     1 MAAPLGPVKFWKPGTEGPGVSISEERQSVTENSGTTIIYNPYAALSIEQQRQKLPVFKLRNHILY 65

  Fly   598 AVTDNQILIVIGETGSGKTTQITQYLGECGFTARGK-IGCTQPRRVAAMSVAKRVAEEYGCRLGQ 661
            .|.:.|.::::||||.||:|||.|||.|.|:||.|: :|.||||||||::||.|||:|.|..||.
Mouse    66 LVENYQTVVIVGETGCGKSTQIPQYLAEAGWTAEGRVVGVTQPRRVAAVTVAGRVADERGAVLGH 130

  Fly   662 EVGYTIRFEDCTSP-ETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTA 725
            ||||.|||:|||.| .|.||::|||||:||.:::..|..|||||||||||||::||:..||||..
Mouse   131 EVGYCIRFDDCTDPLATRIKFLTDGMLVREMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKI 195

  Fly   726 VQKRPELKLIVTSATLDAVKFSQYFFK----------APIFTIPGRTFPVEVLYTKEPETDYLDA 780
            .:||.:|:|||.||||||.||..:|.:          :...|:.||||||::.|.:.|..||:.|
Mouse   196 QKKRGDLRLIVASATLDAEKFRDFFNQNETSDPARDTSVTLTVEGRTFPVDIFYLQSPVPDYIKA 260

  Fly   781 SLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPD--VPELIILPVYSALPSEMQT 843
            ::.||::||..|..||||.|||||||::|...:|.|:.::|...  ...|.:||:|:.|||..|.
Mouse   261 TVDTVVKIHQTEGDGDILAFLTGQEEVETVVSMLIEQARALARTGMKKHLRVLPMYAGLPSFEQM 325

  Fly   844 RIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQR 908
            ::|:......|||::|||:||||:||.||.||:|.||:|.:.||.:|.::.|||.|:|||:|.||
Mouse   326 KVFERVSHSVRKVIVATNVAETSITISGIVYVIDCGFMKLRAYNPRTAIECLVVVPVSQASANQR 390

  Fly   909 AGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVE 973
            |||.||...||.||||||.|: |::..:.|||:||:|||..:||||.:||:::|.|.||..||.:
Mouse   391 AGRGGRNRSGKCYRLYTEEAF-DQLPQSTVPEMQRSNLAPVILQLKALGIDNVLRFHFMSPPPAQ 454

  Fly   974 SLVMALEQLHSLSALDDEGLLTR-LGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQN 1037
            |:|.|||.|::|..||.:..||. ||.|:|||||.|..:|||:.|....||.|:|:|.:|:.:||
Mouse   455 SMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEVLSIAAMMQIQN 519

  Fly  1038 VFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSW-KNNKFSNAWCYENFVQIRTLKRSQDVRK 1101
            ||..|.::::.|.:...||...||||||:|.||.:: |:|| |:.||.|:|:..:.|.|:..||.
Mouse   520 VFVFPSNQKSQATRVHRKFAVEEGDHLTMLNVYEAFIKHNK-SSQWCQEHFLNYKGLVRAATVRD 583

  Fly  1102 QLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALF-NR 1165
            ||..::.:.::..||:..:...:.:.|.||||.|||:......|||:.|...::|||:|.|: .:
Mouse   584 QLKKLLVKFQVPKVSSEGDPDPVLRCIVSGFFANAARFHSSGAYRTIRDDHELHIHPASVLYAEK 648

  Fly  1166 QPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLE 1220
            .|.||||:|::||:|.|||:||.|:..||:|.||.|::  ..|.||...|..:::
Mouse   649 PPRWVIYNEVIQTSKYYMRDVTAIESAWLLELAPHFYQ--QGTHLSLKAKRAKVQ 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189
		HrpA	573..1221	CDD:224557	316/675 (47%)
Dhx35	NP_001359442.1	HrpA	21..682	CDD:224557	311/662 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.720