Protein Alignment pea and Dhx16

DIOPT Version :9

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_006524936.1
• Gene: Dhx16 / 69192
• MGIID: 1916442
• Length: 1049
• Species: Mus musculus
• Alignment Length: 1235
• Identity: 470/1235 - (38%)
• Similarity: 674/1235 - (54%)
• Gaps: 240/1235 - (19%)

  Fly    19 ELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQNLQRIINLMRPSR----- 78
            ||.:.||::::.:|:|:|....:..:.:.|.:.|.|.     |:|        :|..|:|
Mouse    14 ELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDT-----DTL--------DLGGPARDFALK 65

  Fly    79 -----PGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKV----------KAK 128
                 |..|..||.....:.:.::.|.|        |.:|...|:|:..|:.          |.|
Mouse    66 LWSKVPRKAVVEKPARAAEREARALLEK--------NRSYKLLEDSESGEEAVGSNGSSLQKKRK 122

  Fly   129 PEKHSETHKKTDMSDVDAAMMELEALAPG--EGATLVRPHKEVSSRDRHKRRSRDRDTKRRSRSR 191
            ..||.....:.|..|.:..:.|......|  :..|..:|    :|.|..:|..|:     |.:..
Mouse   123 RRKHLRKKHQEDEEDEEEEVSESGKRKAGGSKSPTEEKP----ASEDEWERTERE-----RLQDL 178

  Fly   192 EDRHSDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTE 256
            |:|.:...|.|.|||:|.|....|.:::.....:.|.:..:...|:...    |.|::||.....
Mouse   179 EERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVP----ELRKKSRREYLA 239

  Fly   257 RRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQLR 321
            :|:|        ||:....|.:.|:.             |.|| .|:|....:|        :|:
Mouse   240 KRER--------EKLEDLEAELADEE-------------VLFG-DVELSRHERR--------ELK 274

  Fly   322 AEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPDG 386
            .:.||.|:           .:.....|::..|           :.....|.|::......|..|
Mouse   275 YKRRVRDL-----------AREYRAAGEQEKL-----------EATNRYHMPKETRGQPARTVD- 316

  Fly   387 PFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFDEETGLLPKD 451
                    :..:.:|..|:|.            .|||..|:
Mouse   317 --------IVEEESGAPGEEQ------------RRWEEAQL------------------------ 337

  Fly   452 EDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQRE 516
                                                   |:.:.....:.|.::|.:.|.:|:.:
Mouse   338 ---------------------------------------GAASLKFGARDAAAQEAKYQLVLEED 363

  Fly   517 QEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVE 581
            :.||.:..:       .|..||..|          .||            ..:...:|..:..|
Mouse   364 ETIEFVRAA-------QLQGDEEPS----------GPP------------LSAQAQQKESIQAV- 398

  Fly   582 QRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARG-KIGCTQPRRVAAM 645
             |:|||::..|::|:.|:.::|:||:.|||||||||||.|||.|.|:|.:| ||.||||||||||
Mouse   399 -RRSLPVFPFREELLAAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAAM 462

  Fly   646 SVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHE 710
            |||.|||.|.|.:||.||||:||||||||..|:::||||||||||.|.|.:|.||||:|:|||||
Mouse   463 SVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHE 527

  Fly   711 RTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPET 775
            ||:|||:||||:|...:.|||||::|.|||||..:||.:|..||:|.||||.|||::.|||.||.
Mouse   528 RTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPEA 592

  Fly   776 DYLDASLITVMQIHLREPPGDILLFLTGQ-----EEIDTACEILYERMKSLGPDVPELIILPVYS 835
            |||:|.:::|:|||:.:||||||:|||||     |||:.|||:|.:|.:.||..:.||::||:|:
Mouse   593 DYLEACVVSVLQIHVTQPPGDILVFLTGQVSAVVEEIEAACEMLQDRCRRLGSKIRELLVLPIYA 657

  Fly   836 ALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPI 900
            .|||:||.|||.|.|.|:||||:|||||||||||:||.||:||||.|||.||.:|||:||.|||.
Mouse   658 NLPSDMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPC 722

  Fly   901 SQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFD 965
            |:|:|.||||||||...||.:||||..||:.|:..|.|||||||:|...||.||::||:||:|||
Mouse   723 SKASANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFD 787

  Fly   966 FMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIV 1030
            |:|.||.|:|::|||||::|.||:..|.||..||:|||.|::|.||||::.|....||:||||:.
Mouse   788 FLDPPPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVA 852

  Fly  1031 SMLSVQN-VFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLK 1094
            :||||.| :|||||||...||..:..|....||||.||.||..|..:.:|:.||||||||.|:::
Mouse   853 AMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMR 917

  Fly  1095 RSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPS 1159
            |::|||:||.|:::|.::.:.|...:.||::|||.||:|.:.|:. .:.||||:...|.|:|||:
Mouse   918 RARDVREQLEGLLERVEVGLTSCQGDYVRVRKAITSGYFYHTARL-TRSGYRTVKQQQTVFIHPN 981

  Fly  1160 SALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSD---------PTKLSKFKK 1215
            |:||.:||.|::|||||.||||:||:|..|:..||:|.||.:::..:         |.|:.|.::
Mouse   982 SSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKVGKTRE 1046

  Fly  1216  1215
            Mouse  1047  1046

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	12/77 (16%)
		HrpA	573..1221	CDD:224557	371/659 (56%)
Dhx16	XP_006524936.1	PTZ00121	<147..>410	CDD:173412	73/442 (17%)
		HrpA	377..1036	CDD:224557	373/683 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730