Protein Alignment pea and Dhx38

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_848467.1
• Gene: Dhx38 / 64340
• MGIID: 1927617
• Length: 1228
• Species: Mus musculus
• Alignment Length: 1294
• Identity: 496/1294 - (38%)
• Similarity: 691/1294 - (53%)
• Gaps: 255/1294 - (19%)

  Fly    57 AEFPDSLVQNLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDD 121
            |..|...:..|..:.:|.|..|     :||..|:.|  |||::           .:|...|||.|
Mouse    41 APAPRPSLLGLDLLASLKRRER-----EEKDDGEDK--KKSRV-----------SSYKDWEESKD 87

  Fly   122 DEKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKR--------- 177
            |:| .|:.|...:..:.                               |.||||.|
Mouse    88 DQK-DAEEESEDQAGRS-------------------------------SRRDRHYRSARVETPSH 120

  Fly   178 ----------RSRDRDTKRR-----SRSREDRHSDRRRSRSRDKERRRRSRSRDNRRRSR--SRE 225
                      |||.|:..||     :.|:|::  ||::.||||::..|:....|.|.|||  ||.
Mouse   121 PGGVSEEFWERSRQRERDRREHGVYASSKEEK--DRKKERSRDRDYDRKRDRADERDRSRHSSRS 183

  Fly   226 DRDRDRDR----------RHK----SSSSRDHHER-------RRRSR---------SRSTERRDR 260
            |||...:|          ||:    ::.||...|.       .|||:         .|.:||..|
Mouse   184 DRDGGSERSSRRNEPESPRHRPKDAATPSRSAWEEDDSGYGSSRRSQWETPSPTPSYRDSERGHR 248

  Fly   261 ---RDRSRDCSEK------MPPPS---AAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEG 313
               |||.|....|      :|.||   ....||                          |:....
Mouse   249 PSTRDRDRSIRSKSSDDTPLPTPSYKYNEWADD--------------------------RRHLGS 287

  Fly   314 LVHISQLRAEGRVTDVTEVV---TRNQTVKVKVMSITGQKVSLSMKEVDQ-----DSGKD--LNP 368
            ...:|  |..||..|..|.:   |..:.          |:.....::.|:     |.|.|  .||
Mouse   288 TPRLS--RGRGRREDGEEGIAFDTEEER----------QQWEDDQRQADRDWYMMDEGYDEFHNP 340

  Fly   369 LSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSP--------ERWEIK 425
            |:::.||  .:|.|                      ::|..:::..|||:.        ||||..
Mouse   341 LAYSSED--YVRRR----------------------EQHLHKQKQKRISAQRRQINEDNERWETN 381

  Fly   426 QMISSGVLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPD 490
            :|::|||:.|.|:   ||:.     :||:.|.:.:.:....||||.|.........||..||:..
Mouse   382 RMLTSGVVHRLEV---DEDF-----EEDNAAKVHLMVHNLVPPFLDGRIVFTKQPEPVIPVKDAT 438

  Fly   491 GSLAQAAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRG--MAAAP 553
            ..||..|...|...::.||||..::.|         :|:|          .||....|  |....
Mouse   439 SDLAIIARKGSQTVRKHREQKERRKAQ---------HKHW----------ELAGTKLGDIMGVKK 484

  Fly   554 PEVPEWKKHVIGGK-------------------KSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAV 599
            .|.|: |.....||                   .|.|.||.  :::||||.|||:.::.:|:..:
Mouse   485 EEEPD-KAMTEDGKVDYRTEQKFADHMKEKSEASSEFAKKK--SILEQRQYLPIFAVQQELLTII 546

  Fly   600 TDNQILIVIGETGSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVG 664
            .||.|:||:||||||||||:||||.|.|:|..|.||||||||||||||||||:||.|..||:|||
Mouse   547 RDNSIVIVVGETGSGKTTQLTQYLHEDGYTDYGMIGCTQPRRVAAMSVAKRVSEEMGGNLGEEVG 611

  Fly   665 YTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKR 729
            |.||||||||..|:|||||||:||||.|.||:|..||.:::||||||:::||||||||:..|.:|
Mouse   612 YAIRFEDCTSENTLIKYMTDGILLRESLREADLDHYSAVIMDEAHERSLNTDVLFGLLREVVARR 676

  Fly   730 PELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPP 794
            .:|||||||||:||.||:.:|...|||.||||||||::|::|.|:.||::|::...:|:||...|
Mouse   677 SDLKLIVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDILFSKTPQEDYVEAAVKQSLQVHLSGAP 741

  Fly   795 GDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIA 859
            ||||:|:.|||:|:...:.:.|.::.| .:.|.|.:||:||.|||::|.:||..||.|.||.::|
Mouse   742 GDILIFMPGQEDIEVTSDQIVEHLEEL-ENAPALAVLPIYSQLPSDLQAKIFQKAPDGVRKCIVA 805

  Fly   860 TNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLY 924
            |||||||||:|||.:|:|.|:.|.||:|.:.|||:|.:.|||||.|.||:|||||||||:.:|||
Mouse   806 TNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPISQANANQRSGRAGRTGPGQCFRLY 870

  Fly   925 TERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALD 989
            |:.||::|:|.|.||||||||||..||.||::|:.|||.|.|||.||.::::.::.||..|.|||
Mouse   871 TQSAYKNELLTTTVPEIQRTNLANVVLLLKSLGVQDLLQFHFMDPPPEDNMLNSMYQLWILGALD 935

  Fly   990 DEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKA 1054
            :.|.||..||.|.||||:|.||||||:|..:.||.|||.|||||||..:|||||.::..:||.:.
Mouse   936 NTGGLTSTGRLMVEFPLDPALSKMLIVSCDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIRE 1000

  Fly  1055 KFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGK 1119
            ||...|.||||.|.||..||||.:|..||.::|:..:.:::.::||.||..||.:.::.:.|.|.
Mouse  1001 KFAVPESDHLTYLNVYLQWKNNNYSTIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGT 1065

  Fly  1120 NSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNR--QPEWVIYHELVQTTKEY 1182
            :...::|.||:.:|..|||......|..:......::||:|:||..  .|::::|||||.|||||
Mouse  1066 DWDIVRKCICAAYFHQAAKLKGIGEYVNIRTGMPCHLHPTSSLFGMGYTPDYIVYHELVMTTKEY 1130

  Fly  1183 MREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKYEEPNAWRISRVRRRR 1241
            |:.||.:|.:||.|..|.|:......| |:.:..:|.:...:..||..|....::|.||
Mouse  1131 MQCVTAVDGEWLAELGPMFYSVKQAGK-SRQENRRRAKEEASAMEEEMALAEEQLRARR 1188

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	3/16 (19%)
		S1_DHX8_helicase	285..363	CDD:240189	11/85 (13%)
		HrpA	578..>1203	CDD:441249	339/626 (54%)
Dhx38	NP_848467.1	HrpA	533..>1147	CDD:441249	333/614 (54%)