Protein Alignment pea and dhx57

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_021336395.2
• Gene: dhx57 / 555250
• ZFINID: ZDB-GENE-030131-4078
• Length: 1425
• Species: Danio rerio
• Alignment Length: 1250
• Identity: 318/1250 - (25%)
• Similarity: 532/1250 - (42%)
• Gaps: 348/1250 - (27%)

  Fly   205 DKERRRRSRSRDNRRRSRSRE--------------DRDRDRDRRHKSSSSRDHHERRRRSRSRST 255
            |:.|.:.|.|:.::::|.|.:              :|.:.:.:.|:||:|||..:..:...|.:.
Zfish   299 DERRIKLSDSKHSKKQSESNQICKFYLRGAGCKFGNRCKFKHQVHESSTSRDFCKASQPGFSNAD 363

  Fly   256 E---RRDRRDRSRDCSEKMPPPSA-AMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVH 316
            .   :.:.|.:........||..| :.||:..:|   :|:::  |....|.|.....:..|.:|:
Zfish   364 APIYQLEIRFQPGSLYPFQPPLVAFSSTDESLSG---AGRLS--VTEYLFGQSLSAAEEGEPVVY 423

  Fly   317 --ISQLRAEGRVTDVTEVVTRNQTVKVKVM---SITGQKVSLSMKEVDQDSGKDLNPLSHAPEDD 376
              ||.|..:|.|.::........:....|:   ::|..|...:...||..:
Zfish   424 TLISSLEEDGPVRELLSAAHHKYSAPPPVLAPPTVTPAKSRSNKNNVDNRT-------------- 474

  Fly   377 ESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDF 441
            .:.||:      |:|||:..:       ..|..:::          |:.|::|.         |.
Zfish   475 SATRDQ------STSTSITEI-------TNHRVKQK----------EVAQILSE---------DI 507

  Fly   442 DEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKE 506
            |:    :..:||||.:.|...||.|              |.|.:
Zfish   508 DD----VQDEEDDEDEEECIPVENE--------------SYVNL--------------------- 533

  Fly   507 RREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSF 571
             |::.:.:.|...|.|             ::|::.|..             |:|:     |:||
Zfish   534 -RKRMVKKTEIRTEQM-------------QEENKKLCR-------------EFKR-----KRSS- 565

  Fly   572 GKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGK--- 633
              :..:::.||||.||.::.|:.:::.:..||:|::.|.||.||||||.|::.: .|...|:
Zfish   566 --RRYISMQEQRQKLPAWQKREAILECLVKNQVLVISGMTGCGKTTQIPQFILD-NFLQTGRPDR 627

  Fly   634 ---IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEA 695
               |.||||||::|::||.|||:|....||...||.||.|...|..|.:.:.|.|:|||....:.
Zfish   628 VANIICTQPRRISAIAVATRVAQERAEALGHSTGYQIRLETVRSSITRLMFCTTGVLLRRLEGDP 692

  Fly   696 ELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPG 760
            ||...:.:::||.||||..:|.|..:||..:.||.:||:|:.||||:|..|||||...|...|||
Zfish   693 ELSGVTHVIVDEVHERTEESDFLLLVLKDLIVKRTDLKVIMMSATLNAELFSQYFNNCPCIHIPG 757

  Fly   761 RTFPVEVLYTKE--PETDYL--------------------------------------------- 778
            ||||||..:.::  .:|.|:
Zfish   758 RTFPVEQFFLEDAIAKTRYVIEDGSPYRRSTKLNRSSGPGGTTGKGRALVEDFDDDGGWSFTSFR 822

  Fly   779 ----------DASL----ITV--------------------MQIHLRE-------------PPGD 796
                      |..|    :||                    :.:.|.|             |||.
Zfish   823 NKESVKDSVPDQQLSQQDLTVRYSNYSKSVVKTLAAMDLDKINMDLVESLLEWIVDGDHSYPPGA 887

  Fly   797 ILLFLTGQEEIDTACEILYERMKS----LGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVV 857
            :|:||.|..||    :.|||:::|    ........::.|::|:|.:|.|..:|.....|..|::
Zfish   888 VLVFLPGLAEI----KQLYEQLQSNRMFNNRRTNRCVVYPLHSSLSNEEQQAVFTRPQNGVTKII 948

  Fly   858 IATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYR 922
            |:|||||||:|||.:.||:|.|.:|:|.|::...|:||....:|:|.|.||.|||||...|..:.
Zfish   949 ISTNIAETSVTIDDVVYVIDSGRMKEKRYDASRSMESLEDVWVSRANALQRKGRAGRVASGVCFH 1013

  Fly   923 LYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGI-----NDLLHFDFMDAPPVESLVMALEQL 982
            |:|...:...:....:|||||..|....|::|.:.:     .|.:....::.|...||..|.::|
Zfish  1014 LFTSHRFEHHLSQQQLPEIQRVPLEQLCLRVKVLEVFAERPLDSVFSQLIEPPTEGSLEAAKQRL 1078

  Fly   983 HSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQA 1047
            .:|.||.||..||.||..:|..|::..:.|::::....:|.|..|||.:.|:.::.|..|.||:.
Zfish  1079 CALGALTDEESLTPLGWHLACLPVDVRIGKLMLLGAIFRCLDPALTIAASLAFKSPFVSPWDKRE 1143

  Fly  1048 LADQKKAKFNQAEGDHLTLLAVYNSWKNN-----KFSNAWCYENFVQIRTLKRSQDVRKQLLGIM 1107
            .|::||..|:.|..|||.|:..|..|.|.     |....:|.|||:.||.|:....:::|...::
Zfish  1144 EANEKKLAFSLANSDHLALMQAYKGWCNAAQSGFKAGYQYCRENFLSIRGLQEIACLKRQFAELL 1208

  Fly  1108 -------DRHKLDVV----SAGKNSV---------------RIQKA-ICSGFFRNAAK-KDPQEG 1144
                   |..|..|:    |.|.:.|               ::..| :|:..:.|..: :.||..
Zfish  1209 SDIGFVKDGLKARVIEKMSSKGSDGVLEATGYEANLNSDNTKLMSAMLCAALYPNVVQVRSPQMK 1273

  Fly  1145 YR-------------------TLVDSQVVYIHPSSALF---NRQPEWVIYHELVQTTKEYMRE-- 1185
            |:                   |..|. .|:|||||..|   :....:::|||.|:|::.::|:
Zfish  1274 YKLTSKGAMKMQPKAEEQRFMTKSDG-AVHIHPSSVNFSVRHYDSPYLVYHEKVKTSRVFIRDCS 1337

  Fly  1186 ------------------------VTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPLYNKY 1226
                                    :.::|..| ::||.:....::..|..:::.:|.||   .|.
Zfish  1338 MVCVYPMVLFGGGQVNVELQRGQFIISLDDGW-IKFAAASHEVAELVKELRWELDQLLE---EKI 1398

  Fly  1227 EEPNAWRISRVRRRR 1241
            :.|:...||..|..|
Zfish  1399 KNPSMDLISCPRGSR 1413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	17/82 (21%)
		HrpA	578..>1203	CDD:441249	238/814 (29%)
dhx57	XP_021336395.2	None