DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pea and ZCCHC17

DIOPT Version :9

Sequence 1:	NP_610928.1	Gene:	pea / 36561	FlyBaseID:	FBgn0086895	Length:	1242	Species:	Drosophila melanogaster
Sequence 2:	NP_001269495.1	Gene:	ZCCHC17 / 51538	HGNCID:	30246	Length:	263	Species:	Homo sapiens

Alignment Length:	225	Identity:	65/225 - (28%)
Similarity:	96/225 - (42%)	Gaps:	49/225 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   265 RDCSEKMPPPSAAMTDDP--EAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQLRAEGRVT 327
            |.||..: |.||...|..  |||......:|.:..:|.|:::.|.||  :||||.:.: :..||.
Human    17 RLCSLNL-PFSAEGADSKGWEAGPESPAVVAMVTDYGAFIKIPGCRK--QGLVHRTHM-SSCRVD 77

  Fly   328 DVTEVVTRNQTVKVKV----MSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPD--G 386
            ..:|:|.....|.||:    |.....|||||||.|:|.:||||:|.:...|.:|..|....|  |
Human    78 KPSEIVDVGDKVWVKLIGREMKNDRIKVSLSMKVVNQGTGKDLDPNNVIIEQEERRRRSFQDYTG 142

  Fly   387 PFSSSTSMLN-----------------LQGNGME----GDEHESRKRV----------TRISSPE 420
            ...:..::||                 :|..|.:    .||.|.::..          ||  :|.
Human   143 QKITLEAVLNTTCKKCGCKGHFAKDCFMQPGGTKYSLIPDEEEEKEEAKSAEFEKPDPTR--NPS 205

  Fly   421 RWEIKQMISSGVLDR----SEMPDFDEETG 446
            |...|:.......||    |:..|.:.:||
Human   206 RKRKKEKKKKKHRDRKSSDSDSSDSESDTG 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	28/81 (35%)
pea	NP_610928.1	HrpA	573..1221	CDD:224557
ZCCHC17	NP_001269495.1	S1_pNO40	45..108	CDD:240191	21/65 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810