DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pea and bgcn

DIOPT Version :9

Sequence 1:	NP_610928.1	Gene:	pea / 36561	FlyBaseID:	FBgn0086895	Length:	1242	Species:	Drosophila melanogaster
Sequence 2:	NP_523832.2	Gene:	bgcn / 47873	FlyBaseID:	FBgn0004581	Length:	1215	Species:	Drosophila melanogaster

Alignment Length:	906	Identity:	181/906 - (19%)
Similarity:	324/906 - (35%)	Gaps:	302/906 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   508 REQKMLQREQEIEAMPTSLNKNWID------PLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGG 566
            |:..|.:.:.|:.|...|:..|..|      |||              |..||.:..|.:..:..
  Fly    94 RKSLMGKEDLELYADLVSMKANASDLPSLHLPLP--------------AIRPPNLRFWTEAQLNF 144

  Fly   567 KKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQI-TQYLGEC-GFT 629
            ..:..|                :.|.|::::::..:::::........|:..: ...|.:| ...
  Fly   145 LTAFLG----------------HSLSDEILQSLYASRVIVYNAALCWDKSVFLPLVILDDCRNKK 193

  Fly   630 ARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLME 694
            :..||.|.:.:.:.|...::|.|..:|.:||:.||..:.:....|..|.|.|.|....||. |..
  Fly   194 SNVKIMCIERQAILATYNSQRTANFFGEQLGETVGIQLPYFSAVSSSTFIIYSTAQYFLRS-LTS 257

  Fly   695 AELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIP 759
            .:.::.|.:::::.|....:||:|...::.|:.....|::::.|...:..||:.:|
  Fly   258 QQFRNISHLVVNDVHLHDPYTDILLSEIRMALSSHQNLRVVLLSQMGNPKKFTDFF--------- 313

  Fly   760 GRTFPVEVLYTKE--PETDYLDA--SLITVMQIH-----LREPP--------------------G 795
            |....:.::...|  |...||:.  |.|.:..||     .:|.|                    |
  Fly   314 GEGLQLNMIKQPEVAPRVSYLNELHSCIALAGIHKGPDIYKEIPEAFRANNPRNEQMDKCLQAYG 378

  Fly   796 DI--------LLF--------------LTGQEEIDTACEI--------------------LYER- 817
            ::        .|:              |||:..:..|.|:                    |:::
  Fly   379 ELGTDAALRPFLYAVNYDLAPVNYRHSLTGKTAVHFASELNKANHLRLLLFMGADPYIVDLFQQN 443

  Fly   818 --------------------------MKSLGPDV----------------PE-----------LI 829
                                      :||..||.                ||           ||
  Fly   444 AISLAAMNGNHECIDVLNSYSLHGYVVKSAKPDFVDYDLIIDIMYLLRTKPEYSPGEYSPGNILI 508

  Fly   830 ILPVY------------SALPSEMQT----RIFD-----------PAPAGSRKVVIATNIAETSL 867
            |||.|            ..|...:|.    .::|           .|...:.|||:||:|.| ||
  Fly   509 ILPTYYHIVKLNYMILSHCLTGSLQECSIFLLYDNMRNDYLQALVNASDETVKVVLATDIIE-SL 572

  Fly   868 TIDGIF-YVVDPGFVKQKVYN--SKTGMD-------------SLVVTPISQAAAKQRAGRAGRTG 916
            .:...| |.:|.......||:  |.:|.|             .|::.|              ..|
  Fly   573 CLKVPFKYQIDTACRLNNVYDTTSCSGDDRFEWVAKDALLRRELILQP--------------NKG 623

  Fly   917 PGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFM----DAPPVESLVM 977
            ..:.:||.::.|| :|:..|..|.:|...|....|.:|.:..|.::. :::    ..||:.::..
  Fly   624 DVQCFRLISKEAY-EELSETSQPSLQTMQLDKICLAVKLLSPNTIIS-EYLGITISPPPLINVHH 686

  Fly   978 ALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLS-------- 1034
            |::.|..:..|||...:|.||.|:.:.|:...|.:|||..:.|:|.|.||||||.||
  Fly   687 AVQFLKKIDVLDDAEDVTWLGCRLMDIPVSCQLGRMLIFGILLRCLDPILTIVSSLSTADPLGIP 751

  Fly  1035 ----VQNVFYR---------PKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKN---NKFSNAWC 1083
                :.|::.|         .|::..|:|      ||. .||...:.:|..|:|   |:....:.
  Fly   752 FTEDIDNLWDRFTIYIQNSIKKERTYLSD------NQF-SDHFIFVRLYKEWQNRMHNRTPPLYL 809

  Fly  1084 ---YENFVQIRTLKRSQDVRKQLLG-------IMDRHKLDVVSAGKNSVR---IQKAICSGFFRN 1135
               || |:....:::...:|.:::.       |..|.||.:.:..:.|..   ::.|:..|.:.|
  Fly   810 KDEYE-FMLNGLMEQLTSIRSEIVSSLRAANLIHSRGKLSMNNLNQMSCNWHMVKAALTGGMYPN 873

  Fly  1136 AAKKDPQEGYRTLVDSQVVYIHPSSAL--------------------FNRQPEWVIYHELV 1176
            ....|.::.......|..|.:||::.|                    .|||...::|..||
  Fly   874 IYAVDTRKSSLKSAFSGNVSMHPNTVLRDFLEPLNISAQSFRTPWIVCNRQKSHIVYATLV 934

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189
pea	NP_610928.1	HrpA	573..1221	CDD:224557	166/835 (20%)
bgcn	NP_523832.2	ANK repeat	406..438	CDD:293786	5/31 (16%)
		ANK	407..>460	CDD:238125	5/52 (10%)
		Ank_2	413..>460	CDD:289560	3/46 (7%)
		HrpA	<484..973	CDD:224557	108/476 (23%)
		HA2	694..763	CDD:214852	24/68 (35%)
		OB_NTP_bind	823..945	CDD:285018	21/112 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810