Protein Alignment pea and spn-E

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_476741.1
• Gene: spn-E / 41919
• FlyBaseID: FBgn0003483
• Length: 1434
• Species: Drosophila melanogaster
• Alignment Length: 723
• Identity: 199/723 - (27%)
• Similarity: 322/723 - (44%)
• Gaps: 141/723 - (19%)

  Fly   567 KKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTAR 631
            ||..|....|       ::|.||..|::::.|:..:.::|:.||||.|||||:.||:.:..:.:
  Fly   103 KKFRFNLNRD-------KNLSIYAKREEILAAINAHPVVIIKGETGCGKTTQVPQYILDEAYKS- 159

  Fly   632 GK---IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPE-TIIKYMTDGMLLRECL 692
            ||   |..|||||:||:|:|.||.:|...:......:.:......|.| |.:.|.|.|:||...:
  Fly   160 GKYCNIVVTQPRRIAAISIANRVCQEREWQQNTVCSFQVGLHRPNSLEDTRLLYCTTGVLLNNLI 224

  Fly   693 MEAELKSYSVIMLDEAHERTIHTDVLFGLLK--TAVQKRPELKLIVTSATLDAVKFSQYFFKA-- 753
            ....|..|:.|:|||.|||..:.|.|..:::  .|...| .:|:|:.|||:||.:.|.||...
  Fly   225 NNKTLTHYTHIVLDEVHERDQNMDFLLIVVRRLLATNSR-HVKIILMSATIDAKELSDYFTTTNS 288

  Fly   754 --PIFTI-PGRTFPVEVLYTKE----------------PETD---YLDASLITVMQIHLREPP-- 794
              |:.|. ..|...:|..|..:                ||.:   |..|..|.|:..::....
  Fly   289 IPPVITTNHRRKHSIEKFYRDQLGSIIWNEEDVGHQQVPEINKHGYRAAVKIIVIIDNMERKAAI 353

  Fly   795 ------------GDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFD 847
                        |.:|:||.|..||||..|.|...::: .|:: ::.|:..:|.:..|.|..:|:
  Fly   354 QSRQSYDEALRYGAVLIFLPGIYEIDTMAENLTCMLEN-DPNI-KVSIVRCFSLMTPENQRDVFN 416

  Fly   848 PAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRA 912
            |.|.|.||:::.|||||:|:|:..:.||:|....|.||.::.:...||.:|..|:|..:|||||.
  Fly   417 PPPPGFRKIILTTNIAESSITVPDVSYVIDFCLAKVKVTDTASSFSSLRLTWASKANCRQRAGRV 481

  Fly   913 GRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVM 977
            ||...|:.||:..:..|:.||....:||:.|..|..:||:.|.:.:..          |||.|.:
  Fly   482 GRLRSGRVYRMVNKHFYQREMPEFGIPEMLRLPLQNSVLKAKVLNMGS----------PVEILAL 536

  Fly   978 A-----LEQLHSLSALDDE----------------GLLTRLGRRMAEFPLEPNLSKMLIMSVALQ 1021
            |     |..:|:...|..|                |.||..|..|:..||:...|:::|:.....
  Fly   537 ALSPPNLSDIHNTILLLKEVGALYLTVDGIYDPLDGDLTYWGTIMSRLPLDTRQSRLIILGYIFN 601

  Fly  1022 CSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGD----------HLTLLAVYNSWKNN 1076
            ..:|.:.|.:.||...:|.....:..|.|.....:..::|.          :||.|.:..:..:.
  Fly   602 MLEEAIIIAAGLSTPGLFAHEGGRSQLGDSFWMHYIFSDGSGSDLVAIWRVYLTYLNIVENGHDQ 666

  Fly  1077 KFSNAWCYENFVQIRTLKR----SQDVRKQL--LGIM-----------DRHK---LDVVSAG--- 1118
            :.:..|.....|.:|:||.    .|::|.:.  ||::           ||.|   |.|:.||
  Fly   667 ESAIRWAKRFHVSLRSLKEIHLLVQELRVRCTHLGLIPFPVNPNQMMDDREKAIMLKVIIAGAFY 731

  Fly  1119 KNSVRIQKAICSGFFRNAAKKDPQEGYRTLV---DSQVVYIHPSSALFNRQPEWV--IYHELVQT 1178
            .|.....|..|:...||.        |:|:.   ..:.||      ..|.:|.::  :|   .:.
  Fly   732 PNYFTRSKESCADTDRNI--------YQTISGHDPCRTVY------FTNFKPAYMGELY---TRR 779

  Fly  1179 TKEYMREV 1186
            .||..:||
  Fly   780 IKELFQEV 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	195/712 (27%)
spn-E	NP_476741.1	HrpA	114..>697	CDD:441249	170/596 (29%)
		DEXHc_TDRD9	115..295	CDD:350746	64/181 (35%)
		TUDOR	892..1016	CDD:425754