Protein Alignment pea and Dhx30

DIOPT Version :9

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_006243888.1
• Gene: Dhx30 / 367172
• RGDID: 1308888
• Length: 1222
• Species: Rattus norvegicus
• Alignment Length: 1270
• Identity: 321/1270 - (25%)
• Similarity: 521/1270 - (41%)
• Gaps: 325/1270 - (25%)

  Fly    60 PDSLVQNLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQ-LLKMFP----------GLALPNDTY 113
            ||. .|....:.:.:.||.||       .||......|: |||.||          |.|| ..::
  Rat    42 PDG-TQEAAEVESEVAPSEPG-------EGDGSMVNASRDLLKEFPQPKNLLNSVIGRAL-GISH 97

  Fly   114 SKKEESDDDEKV--------KAKPEKHSETHKKTDMSDVDAAMMELEALAPG------EGATLVR 164
            :|      |:.|        |.|...|.:..|..::....:..::.|..|..      :|..|:.
  Rat    98 AK------DKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLG 156

  Fly   165 PHKEVSSRDRHKRRSRDRDTKRRSRSREDRHSDRRRSRSRDKERRR----RSRSRDNRR------ 219
            |..|:....::             |...||......|..|.:....    |..:.:|.|
  Rat   157 PRNELFDAAKY-------------RVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPAGTGG 208

  Fly   220 --RSRSREDRDRDRDRRHK---------SSSSRDHHERRRRSRSRSTERRDRRDRSRDCSEKMPP 273
              ||..||:.:.:.:...:         |.:.:|.|...|.||..|.|..|.....|..:: .|.
  Rat   209 LSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQ-FPL 272

  Fly   274 PSAAMTDDPEAGKIY-----SGKIANIVPF---GCFVQLFGLRKRWE-GLVHISQLRAEGRVTDV 329
            |...:      .|:.     |....|::.|   |...:|..|...|. .:..:    |:||
  Rat   273 PKNLL------AKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFV----AKGR---- 323

  Fly   330 TEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSM 394
                 |....:.|..::..:|:. |:..||:::    .||:||..:..|||:..
  Rat   324 -----RKAEAENKAAALACKKLK-SLGLVDRNN----EPLTHAMYNLASLRELG----------- 367

  Fly   395 LNLQGNGMEGDEHESRKRVTRISSPE--RWEIKQMISSGVLDRSEM-PDFD-EETGLLP--KDED 453
                         |:::|...|..||  ..:|:..:|...:|.|.: |:.. :...:||  ||..
  Rat   368 -------------ETQRRPCTIQVPEPILRKIEAFLSHYPVDSSWISPELRLQSDDILPLGKDSG 419

  Fly   454 DEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQREQE 518
            ..:|          |..   |:....||....|:          :.||.|...||
  Rat   420 PLSD----------PIT---GKPYMPLSEAEEVR----------LSQSLLELWRR---------- 451

  Fly   519 IEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQR 583
                                        ||        |.|                     ::.
  Rat   452 ----------------------------RG--------PIW---------------------QEA 459

  Fly   584 QSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGEC----GFTARGKIGCTQPRRVAA 644
            ..||:...||.::.|:..:.::::.|:||.||||:|.|.|.|.    |..||..:..|||||::|
  Rat   460 PQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISA 524

  Fly   645 MSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPET---IIKYMTDGMLLRECLMEAELKSYSVIMLD 706
            :|||:||:.|.|..|.:.||:.:|.|  :.|..   .:.:.|.|:|||:......|:..|.:::|
  Rat   525 VSVAQRVSHELGPSLRRNVGFQVRLE--SKPPARGGALLFCTVGILLRKLQSNPSLEGVSHVIVD 587

  Fly   707 EAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTK 771
            |.|||.::||.|..|||...:..|.|:|::.|||.|..:||:||...|:..:||..:||:..|.:
  Rat   588 EVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLE 652

  Fly   772 ------------------EPETD-YLDASLITVMQIHL--REPPGDILLFLTGQEEIDTACEILY 815
                              |.|.: .||..|:|.:.:|:  |..||.||.||.|.:||....:.|.
  Rat   653 DILAKLGKHQYPHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQ 717

  Fly   816 ERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGF 880
            |   :||....:.:||||:|.:|...|..||...|.|.||:|:||||||||:|::.|.:|||.|.
  Rat   718 E---ALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGL 779

  Fly   881 VKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTN 945
            .|::.|:.||.:..|....:|:|...||.|||||...|..|.|: .|:..::|:|..||||.||.
  Rat   780 HKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLF-PRSRLEKMVPFQVPEILRTP 843

  Fly   946 LATTVLQLKTMGINDLLHF------DFM----DAPPVESLVMALEQLHSLSALDDEGLLTRLGRR 1000
            |...|||.|       :|.      :|:    |:|.::::..|:..|..:..||....||.||:|
  Rat   844 LENLVLQAK-------IHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQR 901

  Fly  1001 MAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEG-DHL 1064
            :|....:|.|:|.::::...:|...:|.:||.|: ::.|......:|..|:.||..:...| |||
  Rat   902 LAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHL 965

  Fly  1065 TLLAVYNSWKN-NKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSA---GKNS-VRI 1124
            ..:.....|:. .::.:....||::: ..|..:..:| .:.|::.:...::..|   ||.| ..:
  Rat   966 AFVRAVAGWEEVLRWQDRTSRENYLE-ENLLYAPSLR-FIHGLIKQFSENIYEAFLVGKPSDCTL 1028

  Fly  1125 QKAIC---------------SGFFRNAAK----KDPQEG--------YRTLVDSQVVYIHPSSAL 1162
            ..|.|               :|.:.|..:    |..::|        |||  .|..:.:|.|:
  Rat  1029 PSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRT--KSGNILLHKST-- 1089

  Fly  1163 FNRQ-----PEWVIYHELVQTT-KEYMREVTTIDP 1191
            .||:     ..|:.|...|::. ..::|:.:.:.|
  Rat  1090 INREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHP 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	17/86 (20%)
		HrpA	573..1221	CDD:224557	213/696 (31%)
Dhx30	XP_006243888.1	DEXDc	466..645	CDD:214692	68/180 (38%)
		DEXDc	480..621	CDD:238005	55/142 (39%)
		HELICc	714..813	CDD:197757	44/101 (44%)
		HA2	885..968	CDD:214852	25/83 (30%)
		OB_NTP_bind	1008..1130	CDD:285018	23/121 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810