Protein Alignment pea and Dhx16

DIOPT Version :9

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_997661.1
• Gene: Dhx16 / 294232
• RGDID: 1302963
• Length: 1044
• Species: Rattus norvegicus
• Alignment Length: 1231
• Identity: 470/1231 - (38%)
• Similarity: 680/1231 - (55%)
• Gaps: 237/1231 - (19%)

  Fly    19 ELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQNLQRIINLMRPSR----- 78
            ||.:.||::::.:|:|:|....:..:.:.|.:.|.|.             ..::|..|:|
  Rat    14 ELHSVLGLSERHVAQFLIGTAQRCASAEEFVQRLRDT-------------ETLDLGGPARDFALK 65

  Fly    79 -----PGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKV----------KAK 128
                 |..|..||.....:.:.::.|.|        |.:|...|:|:..|:.          |.|
  Rat    66 LWSKVPRKAVVEKPARAAEREARALLEK--------NRSYKLLEDSESGEEAVARDGSSLQKKRK 122

  Fly   129 PEKHSETHKKTDMSDVDAAMMELEALAPGE---GATLVRPHKEVSSRDRHKRRSRDRDTKRRSRS 190
            ..||....::.:..:      |.||...|:   |.:.....::.:|.|..:|..|:     |.:.
  Rat   123 RRKHLRKKQQEEEEE------EEEASESGKRKTGGSKSPTEEKPASEDEWERTERE-----RLQD 176

  Fly   191 REDRHSDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRST 255
            .|:|.:...|.|.|||:|.|....|.:::.....:.|.:..:...|:...    |.|::||....
  Rat   177 LEERDAFAERVRQRDKDRTRNVLERSDKKAYEEAQKRLKMAEEDRKAMVP----ELRKKSRREYL 237

  Fly   256 ERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQL 320
            .:|:|        ||:....|.:.|:.             |.|| .|:|....:|        :|
  Rat   238 AKRER--------EKLEDLEAELADEE-------------VLFG-DVELSRHERR--------EL 272

  Fly   321 RAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPD 385
            :.:.||.|:           .:.....|::..|           :.....|.|::..
  Rat   273 KYKRRVRDL-----------AREYRAAGEQEKL-----------EATNRYHMPKETR-------- 307

  Fly   386 GPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFDEETGLLPK 450
            |..:.:|.::. :.:|..|:|.            .|||
  Rat   308 GQPARATDIVE-EESGAPGEEQ------------RRWE--------------------------- 332

  Fly   451 DEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQR 515
                ||.::.                              .||...|  :.|.::|.:.|.:|:.
  Rat   333 ----EARLDA------------------------------ASLKFGA--RDAAAQEPQYQLVLEE 361

  Fly   516 EQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLV 580
            ::.||.:..:       .|..||..|         :.||            ..:...:|..:..|
  Rat   362 DETIEFVRAA-------QLQGDEEPS---------SGPP------------LSAQAQQKESIQAV 398

  Fly   581 EQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARG-KIGCTQPRRVAA 644
              |:|||::..|::|:.|:.::|:||:.|||||||||||.|||.|.|:|.:| ||.|||||||||
  Rat   399 --RRSLPVFPFREELLTAIANHQVLIIEGETGSGKTTQIPQYLFEEGYTKKGMKIACTQPRRVAA 461

  Fly   645 MSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAH 709
            ||||.|||.|.|.:||.||||:||||||||..|:::||||||||||.|.|.:|.||||:|:||||
  Rat   462 MSVAARVAREMGVKLGNEVGYSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAH 526

  Fly   710 ERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPE 774
            |||:|||:||||:|...:.|||||::|.|||||..:||.:|..||:|.||||.|||::.|||.||
  Rat   527 ERTLHTDILFGLIKDVARFRPELKVLVASATLDTARFSAFFDDAPVFRIPGRRFPVDIFYTKAPE 591

  Fly   775 TDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPS 839
            .|||:|.:::|:|||:.:||||||:||||||||:.|||:|.:|.:.||..:.||::||:|:.|||
  Rat   592 ADYLEACVVSVLQIHVTQPPGDILVFLTGQEEIEAACEMLQDRCRRLGSKIRELLVLPIYANLPS 656

  Fly   840 EMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAA 904
            :||.|||.|.|.|:||||:|||||||||||:||.||:||||.|||.||.:|||:||.|||.|:|:
  Rat   657 DMQARIFQPTPPGARKVVVATNIAETSLTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKAS 721

  Fly   905 AKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDA 969
            |.||||||||...||.:||||..||:.|:..|.|||||||:|...||.||::||:||:||||:|.
  Rat   722 ANQRAGRAGRVAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLKSLGIHDLMHFDFLDP 786

  Fly   970 PPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLS 1034
            ||.|:|::|||||::|.||:..|.||..||:|||.|::|.||||::.|....||:||||:.:|||
  Rat   787 PPYETLLLALEQLYALGALNHLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAAMLS 851

  Fly  1035 VQN-VFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQD 1098
            |.| :|||||||...||..:..|....||||.||.||..|..:.:|:.||||||||.|:::|::|
  Rat   852 VNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQFRSMRRARD 916

  Fly  1099 VRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALF 1163
            ||:||.|:::|.::.:.|...:.||::|||.||:|.:.|:. .:.||||:...|.|:|||:|:||
  Rat   917 VREQLEGLLERVEVGLTSCQGDYVRVRKAITSGYFYHTARL-TRSGYRTVKQQQTVFIHPNSSLF 980

  Fly  1164 NRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSD---------PTKLSKFKK 1215
            .:||.|::|||||.||||:||:|..|:..||:|.||.:::..:         |.|:.|.::
  Rat   981 EQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAKELEDPHAKKMPKKVGKTRE 1041

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	12/77 (16%)
		HrpA	573..1221	CDD:224557	371/654 (57%)
Dhx16	NP_997661.1	DEXDc	402..584	CDD:214692	118/181 (65%)
		DEXDc	419..558	CDD:238005	97/138 (70%)
		HELICc	583..740	CDD:238034	99/156 (63%)
		HA2	801..885	CDD:214852	43/83 (52%)
		OB_NTP_bind	920..1018	CDD:285018	47/98 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X141
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730