Protein Alignment pea and Dhx8

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_001400156.1
• Gene: Dhx8 / 287727
• RGDID: 1310723
• Length: 1242
• Species: Rattus norvegicus
• Alignment Length: 1265
• Identity: 888/1265 - (70%)
• Similarity: 1017/1265 - (80%)
• Gaps: 67/1265 - (5%)

  Fly     2 DELQKLEYLSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQN 66
            :||.||||||||||:||||||||||||||||||:|.|..||.|:|||:.:|:.|||||.|||:.|
  Rat    20 EELAKLEYLSLVSKVCTELDNHLGINDKDLAEFVISLAEKNTTFDTFKASLVKNGAEFTDSLISN 84

  Fly    67 LQRIINLMRPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKVKAKPEK 131
            |.|:|..|||......|::..|..|.|  |.:|.::||.|..|::...:....::|.||.
  Rat    85 LLRLIQTMRPPAKPSTSKDPVVKPKTE--KEKLKELFPVLCQPDNPSVRTMLDEEDVKVA----- 142

  Fly   132 HSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRSRDRDTKRRSRSREDRHS 196
                        || .:.|||||.|.......:...|...|.:.|:|||.||   |.|.| ||..
  Rat   143 ------------VD-VLKELEALMPSAAGQEKQRDTEHRDRTKKKKRSRSRD---RDRDR-DRDR 190

  Fly   197 DRRRSRSRDKERRR-RSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDH---HER-----RRRSRS 252
            ||.|.|.|||:|.| |.|.||..|      |||||..|||: |.||.|   .||     |.||||
  Rat   191 DRDRDRDRDKDRERDRDRERDRER------DRDRDHKRRHR-SRSRSHSRTRERAKGKSRYRSRS 248

  Fly   253 RS----TERRDRR-------DRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFG 306
            ||    .:|:||.       ||.||.....|||     ::|..|.||:||:.:|:.|||||||.|
  Rat   249 RSQSPFKDRKDREKYGERNLDRWRDKHVDRPPP-----EEPAIGDIYNGKVTSIMQFGCFVQLEG 308

  Fly   307 LRKRWEGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNP--- 368
            ||||||||||||:||.||||.:|.:||::.|.|||||:|.||.|.|||||:|||::|:||||
  Rat   309 LRKRWEGLVHISELRREGRVANVADVVSKGQRVKVKVLSFTGTKTSLSMKDVDQETGEDLNPNRR 373

  Fly   369 LSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVL 433
            .:...|.:|....||||.|    |.:..:....:|.|..| |||:||||.||:|||||||::.||
  Rat   374 RNLVGETNEETSMRNPDRP----THLSLVSAPEVEDDSLE-RKRLTRISDPEKWEIKQMIAANVL 433

  Fly   434 DRSEMPDFDEETGLLPK--DEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQA 496
            .:.|.||||||||:|||  ||:|| |:|||:||||||||.||.:...|:||::|||||||||:||
  Rat   434 SKEEFPDFDEETGILPKVDDEEDE-DLEIELVEEEPPFLRGHTKQSMDMSPIKIVKNPDGSLSQA 497

  Fly   497 AMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKK 561
            |||||||:|||||.|..|||.|::::|..|||:|:||||:.|.|.:||||||:...|.::|||||
  Rat   498 AMMQSALAKERRELKQAQREAEMDSIPMGLNKHWVDPLPDAEGRQIAANMRGIGMMPNDIPEWKK 562

  Fly   562 HVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGEC 626
            |..||.|:|:||||.::::|||:|||||||::.|::||.|||||||||||||||||||||||.|.
  Rat   563 HAFGGNKASYGKKTQMSILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAEA 627

  Fly   627 GFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLREC 691
            |:|:|||||||||||||||||||||:||:||.|||||||||||||||||||:|||||||||||||
  Rat   628 GYTSRGKIGCTQPRRVAAMSVAKRVSEEFGCCLGQEVGYTIRFEDCTSPETVIKYMTDGMLLREC 692

  Fly   692 LMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIF 756
            |::.:|..|::|||||||||||||||||||||..||||.::||||||||||||||||||::||||
  Rat   693 LIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIF 757

  Fly   757 TIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSL 821
            ||||||:|||:|||||||||||||||||||||||.|||||||:||||||||||||||||||||||
  Rat   758 TIPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKSL 822

  Fly   822 GPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVY 886
            |||||||||||||||||||||||||||||.|||||||||||||||||||||:|||||||||||||
  Rat   823 GPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDGIYYVVDPGFVKQKVY 887

  Fly   887 NSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVL 951
            |||||:|.|||||||||.|||||||||||||||.||||||||||||||.|.||||||||||:|||
  Rat   888 NSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRDEMLTTNVPEIQRTNLASTVL 952

  Fly   952 QLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIM 1016
            .||.|||||||.||||||||:|:|:.|:|||::|.||||||||||||||||||||||.|.|||||
  Rat   953 SLKAMGINDLLSFDFMDAPPMETLITAMEQLYTLGALDDEGLLTRLGRRMAEFPLEPMLCKMLIM 1017

  Fly  1017 SVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNA 1081
            ||.|.||:|:||||||||||||||||||||||||||||||:|.|||||||||||||||||||||.
  Rat  1018 SVHLGCSEEMLTIVSMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNP 1082

  Fly  1082 WCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYR 1146
            ||||||:|.|:|:|:||:|||:|||||||||||||.||::||:||||||||||||||||||||||
  Rat  1083 WCYENFIQARSLRRAQDIRKQMLGIMDRHKLDVVSCGKSTVRVQKAICSGFFRNAAKKDPQEGYR 1147

  Fly  1147 TLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLS 1211
            ||:|.|||||||||||||||||||:|||||.||||||||||||||:|||||||:||:.|||||||
  Rat  1148 TLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSDPTKLS 1212

  Fly  1212 KFKKNQRLEPLYNKYEEPNAWRISRVRRRR 1241
            |.||.||||||||:|||||||||||..|||
  Rat  1213 KQKKQQRLEPLYNRYEEPNAWRISRAFRRR 1242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	48/66 (73%)
		S1_DHX8_helicase	285..363	CDD:240189	53/77 (69%)
		HrpA	578..>1203	CDD:441249	541/624 (87%)
Dhx8	NP_001400156.1	GH2-like_DHX8	25..92	CDD:409668	48/66 (73%)
		S1_DHX8_helicase	287..365	CDD:240189	53/77 (69%)
		HrpA	578..>1204	CDD:441249	541/625 (87%)