Protein Alignment pea and dhx37

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_593520.1
• Gene: dhx37 / 2543371
• PomBaseID: SPAPB1A10.06C
• Length: 1183
• Species: Schizosaccharomyces pombe
• Alignment Length: 1227
• Identity: 340/1227 - (27%)
• Similarity: 548/1227 - (44%)
• Gaps: 295/1227 - (24%)

  Fly   198 RRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTE------ 256
            |.|.|..:|.|:...:...|.:|:|..      |..|.:.|||..|......::..:.|
pombe     3 RLRKRFNEKGRQSGIQKMLNLKRARLH------RSVREQESSSEVHANPEPDNQDSNAEILIDVP 61

  Fly   257 RRDRRDRSRDCSEKMPPPSAAMTDDPE--------AGKIYSGKIANIVPFGCFVQLFGLRKRWEG 313
            :.:|:.|.::..:::...:.......:        ..|:...::|:::
pombe    62 KEERQKRKQELKDQLLKENEGSISSKKKKRLDKYIENKLKKEEVASLI----------------- 109

  Fly   314 LVHISQLRAEGRVTDVTEVVTRNQTVKVKV-MSITGQKVSLSMKEVDQ----------DSGKDLN 367
             ..:::.|.:..:...::.:.:..|.|.|: .|:..:|:.|.:.:.|.          .:.|...
pombe   110 -AKLAEERIDTSLLSSSKNLGKQATAKEKLKKSLLEEKLGLPLSDADSRLYKVVDVETTTTKSST 173

  Fly   368 PLSHAPE---------------DDES---------------------LRDRNPDGPFSSSTSMLN 396
            ..::|||               .:||                     :.:.:|:.. |:....|:
pombe   174 AETNAPEKYSTRSGFGFGFSTGTNESEITPNIKVLPPKKKKNASWGKMLNEDPEYD-SAEEDYLS 237

  Fly   397 LQGNGMEGDEHESRKRVTRISSPERWEIKQMISSGVLD-RSEM--------PDFDEETGLLPKDE 452
            ........|...|.:.....:.|...:.::.:...|:: |||.        |:|:.|...|...|
pombe   238 TDSEEFSEDSDNSSEENKDTNEPSTKDAEKTVPEDVVNLRSEQKLQPSFGHPEFENEDFDLETSE 302

  Fly   453 DDEADIEIEIVEEEPPFLS---------GHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERR 508
            ||.:|   :..|....|.|         ..|...||::|...:.|||..:.:|         :|.
pombe   303 DDSSD---DATERASRFKSWANKQILGADVGEKSHDVAPDNKIDNPDADMVRA---------QRM 355

  Fly   509 EQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGK 573
            .:|:..||:::|  ||:      |.:                       |.|           |:
pombe   356 PRKLKMREEDVE--PTA------DDI-----------------------EIK-----------GR 378

  Fly   574 KTDLTLV-------EQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTA- 630
            ||..|::       |.|.:|||......:::.:..|.::|:.|.||||||||:.|:|.|.||::
pombe   379 KTTYTIINRPPEIQESRLALPIVAEEQRIMEQIFANDVVIICGATGSGKTTQLPQFLFEAGFSSP 443

  Fly   631 ----RGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLREC 691
                .|.|..||||||||:|:||||:||. .....:|.|.|||:...:|:|.||:||||:||||.
pombe   444 ESENPGMIAITQPRRVAAVSIAKRVSEEL-TGFSSKVSYQIRFDSTINPDTAIKFMTDGILLREL 507

  Fly   692 LMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPE----------LKLIVTSATLDAVKF 746
            ..:..|.:||.:::||||||:::||:|.|||...|:.|.|          ||||:.||||....|
pombe   508 SSDFLLTAYSAVIVDEAHERSVNTDILLGLLSRIVRLRREMSKSDQKVKPLKLIIMSATLRVTDF 572

  Fly   747 SQ----YFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEI 807
            |:    :....||..|..|.:||.:.:.:..:.|||..:...|..||.|.|.|.||:|||||:|:
pombe   573 SENKLLFSVPPPIIKIDARQYPVSIHFNRTTKPDYLQDAFDKVCLIHKRLPAGSILVFLTGQQEV 637

  Fly   808 DTACEILYER-MKSLGP-----------------------------DVP--------------EL 828
            :..|::|.:| ::|..|                             .||              .:
pombe   638 EQLCQMLRKRFVRSFRPLKSRARIVVSRKTMSVENEDLQSETEDIDQVPTSSSSSVTYDDESEPM 702

  Fly   829 IILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMD 893
            .:||:||.|.:|.|.::||.:|.|.|..::|||:||||:||..|.||||.|..|::|||.||.:.
pombe   703 YVLPLYSLLTTEDQMKVFDSSPEGHRMCIVATNVAETSITIPNIRYVVDCGKAKERVYNEKTSVQ 767

  Fly   894 SLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPT-PVPEIQRTNLATTVLQLKTMG 957
            ...|..||:|.|.||||||||||||..||||:...: |...|. .:|||.||.:.:.|||:|.|.
pombe   768 KFEVRWISKANADQRAGRAGRTGPGHCYRLYSSAVF-DSSFPLHSLPEILRTPVESIVLQMKNMN 831

  Fly   958 INDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQC 1022
            |:::.:|.|..:|....|..:|:.|.:|.|:|.||:||:||.:|:.|||.|..|||||:.....|
pombe   832 IDNIANFPFPTSPGRSRLEKSLKLLSNLGAIDSEGVLTKLGEQMSLFPLSPRFSKMLIIGQQHGC 896

  Fly  1023 SDEILTIVSMLSV-------QNVFYRPKDKQALAD-----------QKKAKFNQAEG-------- 1061
            ...::.:||.||:       |::.|...||.:.::           ||:...|:..|
pombe   897 LPYVIALVSALSINQLFVSKQSLLYDAHDKNSRSEETDLIDDDEIKQKEEYKNRMRGYFNAISRF 961

  Fly  1062 -------DHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGK 1119
                   ..|:||:...::........:|.||:::.:.|:...::|||::|::.|:   :|...|
pombe   962 QAIDPDAPALSLLSAVCAYDYASDKRKFCKENYLREKALEEVTNLRKQIIGLLKRY---MVRVEK 1023

  Fly  1120 NSVRIQ---------KA----ICSGFFRNAAKKDPQE-GYRTLV--DSQVVYIHPSSALFNRQPE 1168
            ...::|         ||    |.|.:....|..|.:: ||.||.  .|:||...|... :|...|
pombe  1024 EFFKLQLKPPTSVQIKALRQFIASAYIDQVALYDKEKRGYVTLFPSGSEVVQFVPDRT-YNIDSE 1087

  Fly  1169 WVIY---HELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQRLEPL 1222
            :|:|   || .::.:.||..:|.|.|:.|...|.:       |.|..:.|.....|:
pombe  1088 YVVYLSLHE-SRSGRVYMSPLTEISPEHLARLAKN-------TTLLSYSKPLSYPPI 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	10/88 (11%)
		HrpA	578..>1203	CDD:441249	261/747 (35%)
dhx37	NP_593520.1	PTZ00108	<69..314	CDD:240271	35/266 (13%)
		HrpA	397..>909	CDD:441249	207/513 (40%)
		OB_NTP_bind	1041..1121	CDD:400182	25/81 (31%)