Protein Alignment pea and cdc28

DIOPT Version :9

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_595686.2
• Gene: cdc28 / 2540707
• PomBaseID: SPBC19C2.01
• Length: 1055
• Species: Schizosaccharomyces pombe
• Alignment Length: 1233
• Identity: 457/1233 - (37%)
• Similarity: 674/1233 - (54%)
• Gaps: 206/1233 - (16%)

  Fly    10 LSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDSLVQNLQRIINLM 74
            :||...:..:..:.||:::..:.|::|.....:.:.:...:.|:..|.:..|..|:.....:...
pombe     1 MSLEQYVSDKAISLLGMSEPSVVEYLIAEAKGSSSSNNLYQKLVSFGMDGDDPAVKEFAHTLYAR 65

  Fly    75 RPSRPGGASQEKTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEESDDDEKVKAKPEKHSETHKKT 139
            .| |.|...:|.....||  |:..:|:|              |..:....:..:|:.| ||
pombe    66 IP-REGSRPKENYNARKK--KEQGILQM--------------ERLNSSYDLLIEPQSH-ET---- 108

  Fly   140 DMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRSRDRDTKRRSRSREDRHSDRRRSRSR 204
                                     |.|.:..:.|.|  :..|:..||.|..::..||..
pombe   109 -------------------------PGKPLKKKSRSK--TPKREIARRQRDEDEWESDEY----- 141

  Fly   205 DKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHHERRRRSRSRSTERRDRRDRS----- 264
             :|....|.|......|.|.:.::.|.:   |||..........|.|....||..|:|..
pombe   142 -EEVVDGSASHPIEEDSVSTDFQNHDYE---KSSDPETERLNDLREREEFEERLRRKDLEAATNE 202

  Fly   265 --RDCSEKMPPPSAA---MTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEGLVHISQLRAEG 324
              .|.|.|......|   :.||||:                          |..|.  |:||.:
pombe   203 FVEDYSSKFSSEELALRKLADDPES--------------------------WRKLA--SELRKK- 238

  Fly   325 RVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDESLRDRNPDGPFS 389
                     :|.|.:|.:..    |::.:..:|:               .|:|.|
pombe   239 ---------SRQQYLKPRAQ----QQLEILRREI---------------RDEEQL---------- 265

  Fly   390 SSTSMLNLQGNGM---EGDEHESRKRVTRISSPERWEIKQMISSGVLDRSEMP-DFDEETGLLPK 450
                   ..|..:   |..|.|.:|.:.||:. ||..:::..:     ..:|| |:..|.|.|.:
pombe   266 -------FAGEKLTQAEIRELEKKKELLRIAE-ERQRLEKQAT-----EYQMPEDYFTEQGKLDR 317

  Fly   451 DEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKERREQKMLQR 515
            ...:|...:                        |...:.:|.       |:.::....||:..:.
pombe   318 KRKEEVLYQ------------------------RYKDSNEGE-------QNEVTMGAAEQQRWEA 351

  Fly   516 EQEIEAMPTSLNKNWIDPLPE------DESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKK 574
            :|..:|:....|: |:.|..:      |||:.:...:....:|...|...|...:         |
pombe   352 QQINKALLFDQNE-WLPPGEKQFDFVFDESQQIDFLLDTKLSAENPVDTDKMTDV---------K 406

  Fly   575 TDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFT-ARGKIGCTQ 638
            .:.:|...|:|||:|:.:|||:||:.:.|:|:::.|||||||||:.|:|.|.|:| ...||.|||
pombe   407 VEKSLESSRKSLPVYQYKDDLLKAINEYQVLLIVAETGSGKTTQLPQFLHEAGYTKGNKKICCTQ 471

  Fly   639 PRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVI 703
            ||||||||||.|||:|...||||||||:||||:.||.:|:|||:||||||||.|.|.:|.|||||
pombe   472 PRRVAAMSVAARVAKEMDVRLGQEVGYSIRFENATSEKTVIKYLTDGMLLREFLTEPDLASYSVI 536

  Fly   704 MLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVL 768
            ::|||||||:|||:||||:|...:.||:||::::|||:||.|||.||.:||:|.:|||.:||::.
pombe   537 IIDEAHERTLHTDILFGLVKDIARFRPDLKVLISSATIDAEKFSAYFDEAPVFYVPGRRYPVDIY 601

  Fly   769 YTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPV 833
            ||.:||.:|:.|::.|::|||..:|.||||:|||||:||:...|.:.|..:.||..:||:|:.|:
pombe   602 YTPQPEANYIQAAITTILQIHTTQPAGDILVFLTGQDEIELMSENMQELCRILGKRIPEIILCPI 666

  Fly   834 YSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVT 898
            |:.||||:|.:||||.|.|:||||:||||||||:||||:.:|:|.|||||.:||.:|||:|||..
pombe   667 YANLPSELQAKIFDPTPPGARKVVLATNIAETSITIDGVNFVIDSGFVKQNMYNPRTGMESLVSV 731

  Fly   899 PISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLH 963
            |.|:|:|.||||||||.||||.:||||.|.|.:|:.....||||||||...||.||::|||:||.
pombe   732 PCSRASADQRAGRAGRVGPGKCFRLYTRRTYNNELDMVTSPEIQRTNLTNIVLLLKSLGINNLLD 796

  Fly   964 FDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILT 1028
            ||||||||.|:|:.:||.|::|.||::.|.||:|||:|||||.:|.|||.||.|....|.:|:|:
pombe   797 FDFMDAPPPETLMRSLELLYALGALNNRGELTKLGRQMAEFPTDPMLSKSLIASSKYGCVEEVLS 861

  Fly  1029 IVSML-SVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRT 1092
            ||||| ...::|||||||...||:.:|.|.|..|||||||.::|.|.:..||..|..|||:|.::
pombe   862 IVSMLGEASSLFYRPKDKIMEADKARANFTQPGGDHLTLLHIWNEWVDTDFSYNWARENFLQYKS 926

  Fly  1093 LKRSQDVRKQLLGIMDRHKLDVVSAGKNSV-RIQKAICSGFFRNAAKKDPQ-EGYRTLVDSQVVY 1155
            |.|::|||.||..:.:|.::::|:....|: .|:|||.:|:|.|||:.|.. :.|||:..:|.||
pombe   927 LCRARDVRDQLANLCERVEIELVTNSSESLDPIKKAITAGYFSNAARLDRSGDSYRTVKSNQTVY 991

  Fly  1156 IHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSKFKKNQR 1218
            |||||::..::|:.:||.|||.|||||.|::|.|.|:||:|.:|.:|:   |..:.:.:|.|:
pombe   992 IHPSSSVAEKKPKVIIYFELVLTTKEYCRQITEIQPEWLLEISPHYFK---PENIEELQKTQK 1051

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189	10/77 (13%)
		HrpA	573..1221	CDD:224557	355/650 (55%)
cdc28	NP_595686.2	RILP-like	226..>294	CDD:304877	23/142 (16%)
		HrpA	389..1033	CDD:224557	352/652 (54%)
		DEXDc	435..574	CDD:238005	90/138 (65%)
		Helicase_C	615..749	CDD:278689	79/133 (59%)
		HA2	817..901	CDD:214852	46/83 (55%)
		OB_NTP_bind	923..1037	CDD:285018	51/113 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53574
OrthoFinder	1	1.000	-	-		FOG0000059
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100085
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X141
TreeFam	0	0.000	Not matched by this tool.
	7	6.720