Protein Alignment pea and prp16

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_595890.2
• Gene: prp16 / 2540006
• PomBaseID: SPBC1711.17
• Length: 1173
• Species: Schizosaccharomyces pombe
• Alignment Length: 1294
• Identity: 478/1294 - (36%)
• Similarity: 698/1294 - (53%)
• Gaps: 226/1294 - (17%)

  Fly    12 LVSKICTELDNHLGIND--KDLAEFIIDLENKNRTYDTFRKALLDNGAEFPDS---LVQNLQRII 71
            |.:|:..:|.:::...|  ..||..::.:...:.:...|..||...| .|.|:   |:.:|.:.|
pombe    10 LFTKLIDKLTDYMSSKDAATSLASRVLTIAKGSSSSTEFSNALHTFG-RFSDNDSVLIYDLCKSI 73

  Fly    72 -----NLMRPSRPGGASQEKTVGDK-----------------KEDKKSQLLKMFPGLALPNDTYS 114
                 ||       |.|::|..|:.                 :|.|||||     ||
pombe    74 IGLETNL-------GISKDKLPGNDGSQVAGLVLSNRSGLKGREPKKSQL-----GL-------- 118

  Fly   115 KKEESDDDEKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRS 179
                  |...|:.|.|| |:...::::|.|:..  .||::...:.....||.   :..::|.|..
pombe   119 ------DVLAVQKKKEK-SQVEGRSELSQVEND--SLESIGNYDRVEFKRPK---NPHEKHFRPL 171

  Fly   180 RDR---DTKRRSRSREDRHSDRRRS---------RSRDKERRRRSRSRDNRRRSRSREDRDRDRD 232
            |.|   |..:...|.:|::  ||.|         .|.:...|||.|::.....|..|.:|..:..
pombe   172 RQRSSVDDHQEFESEDDKY--RRNSYSSWSGSNFESSNGSNRRRYRTQMEEPLSSKRRNRFGNGS 234

  Fly   233 RRHKSSSSRDHHERRRRSRSRSTERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVP 297
            ||...||...|..........|.:.||         .:.|      .:|||:.
pombe   235 RRDVDSSKYSHDSDYSYGAHSSWDARD---------VEYP------EEDPESK------------ 272

  Fly   298 FGCFVQLFGLRKRW-EGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQD 361
                    ..|:|| |...|:.                |:..:..:..::.|.:|.
pombe   273 --------ADRQRWEEEQAHLD----------------RDWYMNSESQNLLGDEVH--------- 304

  Fly   362 SGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQ 426
                 ||.|    |.|::.||..:..|.....            :|.|.:...|......||..:
pombe   305 -----NPFS----DFETVEDRAHEAEFIEKQK------------KHLSIEASDRFKENSMWEKNR 348

  Fly   427 MISSGVLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDG 491
            ||:|||   |:.|..:.:..|:     :|..:.:.:.|..|.||.|...:...:..:..|::|..
pombe   349 MITSGV---SKAPGLESDYSLM-----EERRVHLLVDELRPHFLDGAEFSSKKVGDITSVRDPQS 405

  Fly   492 SLAQAAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPE- 555
            .||..|.:.|.|.:||||   .:..|:..:..|||            :.:...|:.|:..:..|
pombe   406 DLAINARLGSRLVRERRE---FRERQKAASAATSL------------AGTSLGNVMGLKDSNDED 455

  Fly   556 -----VPEWKKHVIGGKKSSFGKKTDLTLV----EQRQSLPIYKLRDDLIKAVTDNQILIVIGET 611
                 .|   ..|.|..:.|..|.|:....    |||:.||.:.:|:.|:..:.|||:|||:|||
pombe   456 AKAGTTP---VKVAGRSEQSNKKDTEFARTKSYREQREFLPAFAVREQLLSVIRDNQVLIVVGET 517

  Fly   612 GSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPE 676
            |||||||:.|:|.|.|:...|.||||||||||||||||||:||.|.|||..|||:|||||.|.|:
pombe   518 GSGKTTQLAQFLYEDGYHRNGMIGCTQPRRVAAMSVAKRVSEEMGVRLGSTVGYSIRFEDVTGPD 582

  Fly   677 TIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATL 741
            |:|||||||:||||.||:..|:.||||::||||||:::||:|.||||..:.:|.::||:|||||:
pombe   583 TVIKYMTDGVLLRESLMQNNLEKYSVIIMDEAHERSLNTDILMGLLKKVLSRRRDIKLLVTSATM 647

  Fly   742 DAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEE 806
            ::.|||.:|..||.|||||||:||::::.|.|.:||::|::..|:||||.:|.||||:|:||||:
pombe   648 NSQKFSDFFGGAPQFTIPGRTYPVDIMFAKAPCSDYVEAAVRQVLQIHLSQPAGDILVFMTGQED 712

  Fly   807 IDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDG 871
            |:..|||:.:|:..| .|.|.|.|||:||.:|:::|.:|||.|..|.||||:||||||||||:.|
pombe   713 IEATCEIIADRLNQL-HDAPRLSILPIYSQMPADLQAKIFDSAEPGVRKVVVATNIAETSLTVHG 776

  Fly   872 IFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPT 936
            |.||||.|:.|.|:||||.|:|:|.|||||||.|.||||||||||||..||||||.||..||..|
pombe   777 ISYVVDTGYCKLKMYNSKLGIDTLQVTPISQANANQRAGRAGRTGPGIAYRLYTEMAYIREMFET 841

  Fly   937 PVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRM 1001
            .:||||||||:.|||.||::|:.::..|||||.||.::|:.:|.:|.:|.|||:.|.||.||::|
pombe   842 TLPEIQRTNLSNTVLILKSLGVEEISDFDFMDRPPNDTLMASLYELWTLGALDNFGKLTTLGKKM 906

  Fly  1002 AEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTL 1066
            :.||::|:|||::|::...:|::||:||||||||.:||||||::...:|..:.|||..|.|||.|
pombe   907 SLFPMDPSLSKLIIIAEDYKCTEEIITIVSMLSVPSVFYRPKERAEESDAAREKFNVPESDHLML 971

  Fly  1067 LAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSG 1131
            |.:|..|:.|.:||:||.::|:..:||||::|:|:||:.||.:.|:.:.|.....: :::.:||.
pombe   972 LNIYQHWQRNGYSNSWCSKHFLHSKTLKRARDIRQQLVEIMSKQKISLESVSDWDI-VRRVLCSA 1035

  Fly  1132 FFRNAAKKDPQEGYRTLVDSQVVYIHPSSALF--NRQPEWVIYHELVQTTKEYMREVTTIDPKWL 1194
            :|..||.......|..|......::|.:|:|:  ...|::|||||||.|:||||..||::||.||
pombe  1036 YFHQAACAKGIGEYVHLRSGMPCHLHVTSSLYGLGYLPDYVIYHELVLTSKEYMNIVTSVDPYWL 1100

  Fly  1195 VEFAPSFF----RFSDPTK------------------------LSKFKKNQRLEPLYNK 1225
            .||...::    ||.:.|:                        ..|..|||  ||:.:|
pombe  1101 AEFGGVYYSVKERFRNETESYDRVFSSKPQLDAQIAADRELDAKQKLAKNQ--EPVKSK 1157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	16/71 (23%)
		S1_DHX8_helicase	285..363	CDD:240189	8/78 (10%)
		HrpA	578..>1203	CDD:441249	338/634 (53%)
prp16	NP_595890.2	HrpA	492..>1087	CDD:441249	323/596 (54%)