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Protein Alignment pea and DHX30

DIOPT Version :10

Sequence 1:	NP_610928.1	Gene:	pea / 36561	FlyBaseID:	FBgn0086895	Length:	1242	Species:	Drosophila melanogaster
Sequence 2:	XP_047303683.1	Gene:	DHX30 / 22907	HGNCID:	16716	Length:	1265	Species:	Homo sapiens

Alignment Length:	982	Identity:	273/982 - (27%)
Similarity:	428/982 - (43%)	Gaps:	201/982 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 SGKDLNPLSHAPEDDESLRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQ 426
            |.:.|||        ||:|   |.||...|.|:    |...|.||.|..:..| |...:...:.|
Human   235 SWRQLNP--------ESIR---PGGPGGLSRSL----GREEEEDEEEELEEGT-IDVTDFLSMTQ 283

  Fly   427 MISSGVLDRS-----EMPDFDEETGLL---PKDEDDEADIEIEIVEEE----------------- 466
            ..|...|..|     ||.|.|.....|   |..::..|.: |:|....
Human   284 QDSHAPLRDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKV-IQIATSSSTAKNLMQFHTVGTKTK 347

  Fly   467 ----------PPFLSGHGR------------ALHDLSPVRIVKNPDGSLAQA----AMMQSALSK 505
                      |......||            |...|..:.:|...:..|..|    |.::.....
Human   348 LSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGET 412

  Fly   506 ERREQKMLQREQEIEAMPTSLN-----KNWIDP---LPEDESRSLAANMRGMAAAP----PEVPE 558
            :||...:...|..:..:.|.||     .:||.|   |..|:...|..: .|..:.|    |.||.
Human   413 QRRPCTIQVPEPILRKIETFLNHYPVESSWIAPELRLQSDDILPLGKD-SGPLSDPITGKPYVPL 476

  Fly   559 WKKHVIGGKKSSFGKKTDLTLVE----------QRQSLPIYKLRDDLIKAVTDNQILIVIGETGS 613
            .:...:         :...:|:|          :...||:...||.::.|:..:.::::.|:||.
Human   477 LEAEEV---------RLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGC 532

  Fly   614 GKTTQITQYLGEC----GFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTS 674
            ||||:|.|.|.|.    |..||..:..|||||::|:|||:||:.|.|..|.:.||:.:|.|  :.
Human   533 GKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLE--SK 595

  Fly   675 PET---IIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIV 736
            |.:   .:.:.|.|:|||:......|:..|.:::||.|||.::||.|..|||...:..|.|:|::
Human   596 PPSRGGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVL 660

  Fly   737 TSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTK------------------EPETD-YLDASL 782
            .|||.|..:||:||...|:..:||..:||:..|.:                  |.|.: .||..|
Human   661 MSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAKLGKHQYLHRHRHHESEDECALDLDL 725

  Fly   783 ITVMQIHL--REPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRI 845
            :|.:.:|:  |..||.||.||.|.:||....:.|.|   :||....:.:||||:|.:|...|..|
Human   726 VTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQE---ALGMHESKYLILPVHSNIPMMDQKAI 787

  Fly   846 FDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAG 910
            |...|.|.||:|:||||||||:||:.|.:|||.|..|::.|:.||.:..|....:|:|...||.|
Human   788 FQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRG 852

  Fly   911 RAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHF------DFM-- 967
            ||||...|..|.|: .|:..::|:|..||||.||.|...|||.|       :|.      :|:
Human   853 RAGRCQSGFAYHLF-PRSRLEKMVPFQVPEILRTPLENLVLQAK-------IHMPEKTAVEFLSK 909

  Fly   968 --DAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIV 1030
              |:|.::::..|:..|..:..||....||.||:|:|....:|.|:|.::::...:|...:|.:|
Human   910 AVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVV 974

  Fly  1031 SMLSVQNVFYRPKDKQALADQKKAKFNQAEG-DHLTLLAVYNS------WKNNKFSNAWCYENFV 1088
            |.|: ::.|......:|..|:.||..:...| |||..:.....      |::......:..||.:
Human   975 SCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLL 1038

  Fly  1089 QIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNS-VRIQKAIC---------------SGFFRNAA 1137
            ...:|:....:.||    ...:..:....||.| ..:..|.|               :|.:.|..
Human  1039 YAPSLRFIHGLIKQ----FSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLI 1099

  Fly  1138 K----KDPQEG--------YRTLVDSQVVYIHPSSALFNRQ-----PEWVIYHELVQTT-KEYMR 1184
            :    |..::|        |||  .|..:.:|.|:  .||:     ..|:.|...|::. ..::|
Human  1100 QVRQGKVTRQGKFKPNSVTYRT--KSGNILLHKST--INREATRLRSRWLTYFMAVKSNGSVFVR 1160

  Fly  1185 EVTTIDP 1191
            :.:.:.|
Human  1161 DSSQVHP 1167

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.