Protein Alignment pea and ddx-15

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_741147.1
• Gene: ddx-15 / 175771
• WormBaseID: WBGene00018967
• Length: 739
• Species: Caenorhabditis elegans
• Alignment Length: 697
• Identity: 342/697 - (49%)
• Similarity: 465/697 - (66%)
• Gaps: 33/697 - (4%)

  Fly   537 DESRSLAANMRGMAAAP--PEVPEWKKHV--IGGKKSSFGKKTD-------LTLVEQRQSLPIYK 590
            |..||.....|..:.:|  ...|:.|:.:  :|..|.......:       ..:.|:|..||:::
 Worm    16 DRRRSPNRRSRSRSRSPHRRSSPDRKRQIGAVGNMKIQINPYNNQPFSNRYWAIWEKRSQLPVWE 80

  Fly   591 LRDDLIKAVTDNQILIVIGETGSGKTTQITQYL---------GECGFTARGKIGCTQPRRVAAMS 646
            .::..::.:.:||.:.::|||||||||||.|:.         |:....|| .:.|||||||||||
 Worm    81 YKEKFMELLRNNQCITLVGETGSGKTTQIPQWAVEFMKQQQQGQPPGQAR-LVACTQPRRVAAMS 144

  Fly   647 VAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHER 711
            ||.|||||....|||||||:||||||.|..|::||.||||||||.:....|..|.|::|||||||
 Worm   145 VATRVAEEMDVVLGQEVGYSIRFEDCISERTVLKYCTDGMLLREAMNSPLLDKYKVLILDEAHER 209

  Fly   712 TIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETD 776
            |:.||:|.||:|..|:.|.::|:::.||||||.||.:||...|:.::||||||||:.:|...|.|
 Worm   210 TLATDILMGLIKEIVRNRADIKVVIMSATLDAGKFQRYFEDCPLLSVPGRTFPVEIFFTPNAEKD 274

  Fly   777 YLDASLITVMQIHL-REPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSE 840
            ||:|::.||:|||: .|..|||||||||||||:.||:.:...:::||.|...|..:|:||.||..
 Worm   275 YLEAAIRTVIQIHMVEEVEGDILLFLTGQEEIEEACKRIDREIQALGADAGALSCIPLYSTLPPA 339

  Fly   841 MQTRIFDPAP------AGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTP 899
            .|.|||:|||      |.|||.||:||||||||||||:.:|:||||.||||||.:..::||:|.|
 Worm   340 AQQRIFEPAPPNRPNGAISRKCVISTNIAETSLTIDGVVFVIDPGFSKQKVYNPRIRVESLLVCP 404

  Fly   900 ISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHF 964
            ||:|:|.|||||||||.|||.:|||||.||..||.....|||.|:||.:.|||||.:|..||:||
 Worm   405 ISKASAMQRAGRAGRTKPGKCFRLYTETAYGSEMQDQTYPEILRSNLGSVVLQLKKLGTEDLVHF 469

  Fly   965 DFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTI 1029
            ||||.|..|:|:.|||.|:.|.|::|:|.||.||..||||||:|.|:||||.|..|.||:|||:|
 Worm   470 DFMDPPAPETLMRALELLNYLQAINDDGELTELGSLMAEFPLDPQLAKMLITSTELNCSNEILSI 534

  Fly  1030 VSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLK 1094
            .:||||...:.||.:.:..||:.||:|...:|||||||.||:|:|.|:....|||:||:..||:|
 Worm   535 TAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFINYRTMK 599

  Fly  1095 RSQDVRKQLLGIMDRHKLDVVSAGKNS----VRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVY 1155
            .:..||.||..:||::.|..||....|    :.|:||:.:|||...|..:....|.|:.|:|:|.
 Worm   600 TADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHLERSGHYVTVKDNQLVN 664

  Fly  1156 IHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFF 1202
            :|||:.| :.:|||.:|:|.|.|||.::|.||.:.|:||::.||.::
 Worm   665 LHPSTVL-DHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYY 710

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	333/645 (52%)
ddx-15	NP_741147.1	HrpA	74..>707	CDD:441249	329/634 (52%)