Protein Alignment pea and ddx-35

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_497420.1
• Gene: ddx-35 / 175308
• WormBaseID: WBGene00022056
• Length: 732
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 289/692 - (41%)
• Similarity: 430/692 - (62%)
• Gaps: 34/692 - (4%)

  Fly   538 ESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDN 602
            |.||    .....||||...:.|.|        ......|.:.:||..|||:|.|..::......
 Worm    41 EERS----TENAGAAPPIEEQLKVH--------NNPYASLNIQQQRIRLPIFKNRGHILYMCERY 93

  Fly   603 QILIVIGETGSGKTTQITQYLGECGFTARGK-IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYT 666
            :.:|::||||.||:||:.|:|.|.|:.|.|: |..|||||||.:::|.|||||..|.||.:||||
 Worm    94 RTIIIVGETGCGKSTQVPQFLLEAGWAADGRQIVITQPRRVAVVTLATRVAEEKDCILGHDVGYT 158

  Fly   667 IRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPE 731
            :||:|.:..:|.:|:||||:||||.|.:..|..||:||:||||||:.:||:|.|||:..:|.|.:
 Worm   159 VRFDDVSDKDTKVKFMTDGLLLREILADPLLSKYSIIMIDEAHERSCNTDILLGLLRKIIQIRND 223

  Fly   732 LKLIVTSATLDAVKFSQYF----------FKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVM 786
            |::||:||||||..|..:|          ..|.|.::.|||.||.|.:||....||..:::.||:
 Worm   224 LRIIVSSATLDAELFKDFFEMNETGNSDKDTAGIISVEGRTHPVAVHHTKTSVPDYCQSAVDTVI 288

  Fly   787 QIHLREPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPA 851
            .||..|.|||||:|||||:|::..||.|.|...:| .:...|.::|.|.|||:..|.:.||..|.
 Worm   289 NIHKHENPGDILVFLTGQDEVEDVCEKLRELAGNL-KNCDRLWVVPCYGALPAREQMKAFDSTPH 352

  Fly   852 GSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTG 916
            |:||||:||||||.|:||.||.||:|.|:||.:..::..|:::|:...:|:|:|:||||||||..
 Worm   353 GTRKVVVATNIAEASITIPGICYVIDTGYVKLRAQHAANGVETLMRVTVSKASAEQRAGRAGRIR 417

  Fly   917 PGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQ 981
            |||.||||.|..: :......||||||..:|:|:||||.:|:.::..|.::..||..:::..||.
 Worm   418 PGKCYRLYPESEF-ERFAEGTVPEIQRCQMASTILQLKALGVQNVHRFHYLSPPPSWAMINGLEL 481

  Fly   982 LHSLSALDDEGLLTR-LGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDK 1045
            |::|.|:|:...||. ||.:||||||.|..||.|:.|....||.|::|||:|:.:|:||..|..:
 Worm   482 LYALGAIDETSQLTSPLGLQMAEFPLPPMHSKCLLKSAEFGCSTEMVTIVAMMQIQDVFITPYRQ 546

  Fly  1046 QALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRH 1110
            :..||..:.||...||||:|:|.|:..:..|..|..||.::||..|.|.|:.:||.||:.::.|.
 Worm   547 RHQADVIRKKFAVEEGDHMTMLNVFTKFVENGRSKKWCSDHFVNYRGLMRADNVRSQLVRLLKRF 611

  Fly  1111 KLDVVSAG---KNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHP-SSALFNRQ-PEWV 1170
            :::.||:.   ..|..|::.:.:|||..||:......|.|:.:|....::. ||.:|.:. |:||
 Worm   612 EIEKVSSRGLINCSENIRQCLVTGFFSQAAQYHYTGKYMTVKESFPFNMYKGSSIMFKKDYPKWV 676

  Fly  1171 IYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLSK 1212
            |:.|::|   :.:|:||.|:|:||.|.||.::.|....:|::
 Worm   677 IFTEVMQ---DSIRDVTVIEPEWLYELAPHYYEFGTEGELAE 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	277/641 (43%)
ddx-35	NP_497420.1	HrpA	95..>703	CDD:441249	269/612 (44%)