Protein Alignment pea and mog-4

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_497027.1
• Gene: mog-4 / 175117
• WormBaseID: WBGene00003392
• Length: 1008
• Species: Caenorhabditis elegans
• Alignment Length: 1239
• Identity: 462/1239 - (37%)
• Similarity: 670/1239 - (54%)
• Gaps: 271/1239 - (21%)

  Fly    10 LSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGAEFP---------DSLVQ 65
            :|:...|..:|.:.:||:|:.:.:::..|..|.::.....:.|.|.| :||         |.|:.
 Worm     1 MSVEQFINDQLHSIVGISDRSICQYVHALAKKAKSAPDLVEKLRDAG-DFPISPAIQSFADQLMS 64

  Fly    66 NLQRIINLMRPSRPGGASQEKTVGDKKEDKKSQL------LKMFPGLALPNDTYSKKEES---DD 121
            .:.|.....|...|       |..:..|.:.::|      |:.:...:.......|::||   ||
 Worm    65 RMPRQATSARQRGP-------TTAELAEQELNRLNRAVGVLEDYSASSTKTKNVRKRKESSSEDD 122

  Fly   122 DEKVKA-KPEKHSETHKKTDM-SDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRSRDRDT 184
            :..:|| ||.|..:..|..|. ||::|...:|:|              :::.||....|...::
 Worm   123 EAPIKASKPGKSVKPSKSDDSESDIEAMEAKLDA--------------DIAERDALAARINKKE- 172

  Fly   185 KRRSRSREDRHSDRRRSRSRDKERRRRSRSR-DNRRRSRSREDRDRDRDRRHKSSSSRDHHERRR 248
                               :||.|....:.| ||:.:..|..|:.|:..|       |.:.::|:
 Worm   173 -------------------KDKTRNVMEKKRDDNKDKEGSSMDKLREESR-------RQYLKKRK 211

  Fly   249 RSRSRSTERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRKRWEG 313
            ..:....|.....|::....||       :|...:|...|..|:
 Worm   212 VDKLEELEAIVHDDQTLFAREK-------LTKREKADMEYRKKV--------------------- 248

  Fly   314 LVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDDES 378
               :...:|.|:..||         :|:|...:.    ..|.|::         |..:..:|:|.
 Worm   249 ---LEYTKAHGKAGDV---------MKMKRYHLP----DASTKQI---------PSQYVEDDEED 288

  Fly   379 LRDRNPDGPFSSSTSMLNLQGNGMEGDEHESRKRVTRISSPERWEIKQMISS----GVLDRSEMP 439
            .|   |.|                :|               .:||.:|:::|    |..|
 Worm   289 FR---PGG----------------DG---------------AKWEEEQLMASMLHLGAKD----- 314

  Fly   440 DFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALS 504
                     .|.::.|.::   :::|:..|:                              .||.
 Worm   315 ---------AKRKEQEFEL---LLDEKVDFI------------------------------QALQ 337

  Fly   505 KERREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKS 569
            .....:::::.|.|
 Worm   338 MPGTNEEVVETEAE--------------------------------------------------- 351

  Fly   570 SFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGK- 633
                |..:::.|.|:|||:|..||..|:||.::|:||:.||||||||||:.|||.|.||...||
 Worm   352 ----KKKMSIEETRKSLPVYAFRDAFIEAVKEHQVLIIEGETGSGKTTQLPQYLYEAGFCEGGKR 412

  Fly   634 IGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELK 698
            |||||||||||||||.|||:|.||:||.:|||:||||||||.:|::|||||||||||.|.|.:|.
 Worm   413 IGCTQPRRVAAMSVAARVADEVGCKLGTQVGYSIRFEDCTSEKTVLKYMTDGMLLREFLNEPDLA 477

  Fly   699 SYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTF 763
            ||||:|:|||||||:|||:||||:|...:.|.:|||:::||||||.|||.:|..||||.||||.|
 Worm   478 SYSVMMIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAEKFSSFFDDAPIFRIPGRRF 542

  Fly   764 PVEVLYTKEPETDYLDASLITVMQIHLREP-PGDILLFLTGQEEIDTACEILYERMKSLGPDVPE 827
            ||::.||:.||.||:||:::|:|||||.:| |||||:||||||||:|..|.|.||.|:||..:.|
 Worm   543 PVDIYYTQAPEADYVDAAIVTIMQIHLTQPLPGDILVFLTGQEEIETVQEALMERSKALGSKIKE 607

  Fly   828 LIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGM 892
            ||.||||:.|||::|.:||:|.|..:||||:||||||||:|||||.||:||||.||..:::::|:
 Worm   608 LIPLPVYANLPSDLQAKIFEPTPKDARKVVLATNIAETSVTIDGINYVIDPGFSKQNSFDARSGV 672

  Fly   893 DSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMG 957
            :.|.|..||:|||.|||||||||||||.:||||..||:.|:...|:||||||||...||.||::|
 Worm   673 EHLHVVTISKAAANQRAGRAGRTGPGKCFRLYTAWAYKHELEEQPIPEIQRTNLGNVVLMLKSLG 737

  Fly   958 INDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQC 1022
            |:||:||||:|.||.|:||:|||||::|.||:..|.||:|||||||||.:|.:|||:|.|...:|
 Worm   738 IHDLVHFDFLDPPPQETLVIALEQLYALGALNHRGELTKLGRRMAEFPCDPCMSKMIIASEKYEC 802

  Fly  1023 SDEILTIVSMLSVQ-NVFYRPKDKQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYEN 1086
            |:||:||.:|||.. .||||||.:...||..:..|....|||:||:.|||.|:.:.||..||.||
 Worm   803 SEEIVTIAAMLSCNAAVFYRPKAQVIHADSARKGFWSPAGDHITLMNVYNKWQESSFSQRWCVEN 867

  Fly  1087 FVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDS 1151
            :||.||:||::|||.||:|:::|.:::..|: .::::|:|||.:|:|.|.:|.|....|:|:...
 Worm   868 YVQHRTMKRARDVRDQLVGLLERVEIETKSS-TDTIKIRKAITAGYFYNVSKLDNTGHYKTVKHK 931

  Fly  1152 QVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFR---FSDPTKLSKF 1213
            ...:.||:|.||...|.||:|.|||.|:||:|||::.|:..||:|.||.:::   ..|.|. .|.
 Worm   932 HTTHPHPNSCLFEETPRWVVYFELVFTSKEFMREMSEIESGWLLEVAPHYYKGRELEDATN-KKM 995

  Fly  1214 KKNQ 1217
            .||:
 Worm   996 PKNK 999

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	16/72 (22%)
		S1_DHX8_helicase	285..363	CDD:240189	10/77 (13%)
		HrpA	578..>1203	CDD:441249	365/627 (58%)
mog-4	NP_497027.1	PTZ00121	<107..363	CDD:173412	72/485 (15%)
		HrpA	355..>980	CDD:441249	364/625 (58%)