Protein Alignment pea and rha-1

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_495890.2
• Gene: rha-1 / 174417
• WormBaseID: WBGene00004355
• Length: 1301
• Species: Caenorhabditis elegans
• Alignment Length: 1028
• Identity: 247/1028 - (24%)
• Similarity: 433/1028 - (42%)
• Gaps: 228/1028 - (22%)

  Fly   321 RAEGR----VTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPEDD--ESL 379
            |.||.    :|...|.:..::||.:|.....|..:..|.|.:::...|     ...|:.:  ..:
 Worm   135 RNEGTHEQYITQKAEEIAASETVDLKSEIHGGWTMENSKKALNEFLQK-----MRLPQVNYGTKI 194

  Fly   380 RDRNPDGPFSSSTSML------NLQGNGMEGDEHESRKRVTRISSPERWEIKQMIS-------SG 431
            |:.|......::..:.      ||.|.|.     .|.|:|:..:.... .::||..       ||
 Worm   195 RESNTVKTMETTAQIFVPQINKNLVGKGT-----GSNKKVSEAACAMN-IVRQMFHLNIMQSYSG 253

  Fly   432 VLDRSEMPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIV-KNPDGSLAQ 495
            .:.:|::....|....:|:      |:...:.|    ::...|..|.:::..... :.|...|..
 Worm   254 PIKKSKVSTLPEIAISIPE------DLSTRVTE----YVRSCGLELPEINETSATPEAPTSLLTD 308

  Fly   496 AAMMQSALSKERREQKMLQREQEIEAMPTSLNKNWIDPLPE---------DESRSLAANMRGMAA 551
            ..:.|..:|:                :.::.|.:|..||..         ||......:|..::.
 Worm   309 VKLAQFPVSE----------------ICSASNISWAPPLQNWNPWRASNIDEEPLAFMSMEQISQ 357

  Fly   552 APPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKT 616
            ...|..::|:          |:..| .:..||..||:.:.|:::::.|.:|::.::.||||.||:
 Worm   358 RIMEKEDFKR----------GEALD-KITAQRGELPVAQYRENIVQTVAENRVTLIKGETGCGKS 411

  Fly   617 TQITQYLGE--------CGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCT 673
            ||:.|:|.|        ..|.|    ..:||||::|:|:|:|||.|.|..:|:..||.:||:..|
 Worm   412 TQVAQFLLESFLENSNGASFNA----VVSQPRRISAISLAERVANERGEEVGETCGYNVRFDSAT 472

  Fly   674 -SPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVT 737
             .|...|.:.|.|:|||  :||..|:..|.:::||.|||.:.||.:..:|:..:....:|::::.
 Worm   473 PRPYGSIMFCTVGVLLR--MMENGLRGISHVIIDEIHERDVDTDFVLIVLREMISTYRDLRVVLM 535

  Fly   738 SATLDAVKFSQYFFK------APIFTIPGRTFPVEVLYTKE------------------------ 772
            |||:|...|:.:|..      .|:.|:.||||||:..|.::
 Worm   536 SATIDTDLFTNFFSSIPDVGPTPVITMHGRTFPVQSFYLEDILHNLQHMPEEPDQKKRKKGGPPP 600

  Fly   773 PETD-------------------YLDASLITVM------------------QIHLREPPGDILLF 800
            |:.|                   .::.||.|.|                  .|..|...|.:|:|
 Worm   601 PDDDEGDEEVDDKGRNMNILTDPSINESLKTAMSRISEKDIPFGVIEAILNDIASRGVDGAVLVF 665

  Fly   801 LTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAET 865
            |.|..||.|.|..|.|..:....:..|  |||::|.|.|:.|.::|:..| |.||::::||||||
 Worm   666 LPGWAEIMTLCNRLLEHQEFGQANKYE--ILPLHSQLTSQEQRKVFNHYP-GKRKIIVSTNIAET 727

  Fly   866 SLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYR 930
            |:|||.:.||:|....|:::|.|...|........|:....||.|||||...|..:.|.::..:.
 Worm   728 SITIDDVVYVIDSCKAKERMYTSNNNMVHFATVWASKTNVIQRRGRAGRVRAGYAFHLCSKMRFE 792

  Fly   931 -------DEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSAL 988
                   .|||..|:.:|     |.|:..|:...:.:.|. ..:..||.:.:|.:...|.::.||
 Worm   793 ALDDHGTAEMLRIPLHQI-----ALTIKLLRLGSVGEFLG-KALQPPPYDMVVESEAVLQAMGAL 851

  Fly   989 DDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDK---QALAD 1050
            |....||.||:.:|..|:||.::|:||:..||.....:..:.|.:|....|. |::|   :....
 Worm   852 DRNLELTSLGKMLARMPIEPVIAKVLILGTALGAGSVMCDVASAMSFPTPFV-PREKHHSRLSGT 915

  Fly  1051 QKKAKFNQAEGDHLTLLAVYNSWK----------NNKFSNAWCYENFVQIRTLKRSQDVRKQLLG 1105
            |:|...|:. .||:.:::|...::          ..:|...:...|.|    ||.:...|:||:.
 Worm   916 QRKFAGNKF-SDHVAIVSVIQGYREAVQMGASAAEREFCERYSLSNPV----LKMTDGARRQLID 975

  Fly  1106 IMDRH-----------KLDVVSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPS 1159
            ::...           .::|....:....::..:....:.|.|.   ..|.|     :|:.|..|
 Worm   976 VLRNQCSFPEDILFDISVNVNGPDRELNLMRSLLVMALYPNVAY---YVGKR-----KVLTIEQS 1032

  Fly  1160 SALFNRQPEWV---------------IYHELVQTTKEYMREVTTIDPKWLVEF 1197
            |||.|:....|               ::.|.|:|.....::::.|....|:.|
 Worm  1033 SALINKYSMLVPMNNRQEMDFPSPLLVFTEKVRTRCISCKQMSVISAIQLLVF 1085

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	11/45 (24%)
		HrpA	578..>1203	CDD:441249	199/742 (27%)
rha-1	NP_495890.2	DSRM_DHX9_rpt1	4..73	CDD:380683
		DSRM_DHX9_rpt2	169..244	CDD:380684	15/85 (18%)
		DEAD-like_helicase_N	325..562	CDD:475120	75/253 (30%)
		HrpA	380..>897	CDD:441249	160/531 (30%)
		OB_NTP_bind	1005..1087	CDD:400182	18/89 (20%)