Protein Alignment pea and mog-5

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_495019.1
• Gene: mog-5 / 173920
• WormBaseID: WBGene00003393
• Length: 1200
• Species: Caenorhabditis elegans
• Alignment Length: 1279
• Identity: 774/1279 - (60%)
• Similarity: 956/1279 - (74%)
• Gaps: 127/1279 - (9%)

  Fly     4 LQKLEYLSLVSKICTELDNHLGINDKDLAEFIIDLENKNRTYDTFRKALLDNGA--EFPDSLVQN 66
            :.:||:||||||:.:|::||.|:.:||:|||:|.|..:|.|:|..:|||...|.  :|.|||...
 Worm     1 MDQLEHLSLVSKVLSEVENHFGVVEKDVAEFVIHLAQENPTFDKLKKALDSQGLGDQFDDSLTAT 65

  Fly    67 LQRIINLM----RPSRPGGASQE--------KTVGDKKEDKKSQLLKMFPGLALPNDTYSKKEES 119
            :.||:..|    :.::.||.|:|        ..:.|.||:.|::|    |.||:.| |..:||::
 Worm    66 ILRIVQSMTAVKKKNKKGGDSKEDIKDSHKITLISDAKEEIKARL----PALAMAN-TAKEKEDN 125

  Fly   120 DDD-----EKVKAKPEKHSETHKKTDMSDVDAAMMELEALAPGEGATLVRPHKEVSSRDRHKRRS 179
            :||     ||::.:.|......|::|                             |.|:|.:.||
 Worm   126 EDDLMAQLEKMEGRYESEKRLQKESD-----------------------------SKRNRSRSRS 161

  Fly   180 RDRDTKRRSRSREDRHSDRRRSRSRDKERRRRSRSRDNRRRSRSREDRDRDRDRRHKSSSSRDHH 244
            |.||.|            ||||||.|::||||||||:: ||.|.|.||||||||....
 Worm   162 RSRDRK------------RRRSRSGDRDRRRRSRSRED-RRDRDRRDRDRDRDRGRGD------- 206

  Fly   245 ERRRRSRSRSTERRDRRDRSRDCSEKMPPPSAAMTDDPEAGKIYSGKIANIVPFGCFVQLFGLRK 309
               ||...|..:||||||..          .|..::..|.||||.|::.:|..||.|:.|.|.|:
 Worm   207 ---RRGDDRQRDRRDRRDDG----------GARKSEVAEIGKIYDGRVNSIQSFGAFITLEGFRQ 258

  Fly   310 RWEGLVHISQLRAEGRVTDVTEVVTRNQTVKVKVMSITGQKVSLSMKEVDQDSGKDLNPLSHAPE 374
            :.||||||||:|.| ||..|.:|:.|.:.|||||..|...|:|||||||||:||:||||..
 Worm   259 KQEGLVHISQIRNE-RVQTVADVLKRGENVKVKVNKIENGKISLSMKEVDQNSGEDLNPRE---- 318

  Fly   375 DDESLRDRNPDG-------PFSSSTSMLNLQGNGMEGDEHES----RKRVTRISSPERWEIKQMI 428
                 .|.|||.       |.:|::|.:|.:.:|:......|    :.|| |||:|||||::||.
 Worm   319 -----TDLNPDAIGVRPRTPPASTSSWMNPEASGVGQGPSTSIGGGKARV-RISTPERWELRQMQ 377

  Fly   429 SSGVLDRSEMPDFDEETGLLPK--DEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDG 491
            .:|||..::|||||||.|:|..  ||.|..|||||:||:||.||.|:|:...::.||::||||||
 Worm   378 GAGVLTATDMPDFDEEMGVLRNYDDESDGEDIEIELVEDEPDFLRGYGKGGAEIEPVKVVKNPDG 442

  Fly   492 SLAQAAMMQSALSKERREQKM-LQREQEIEAMP-TSLNKNWIDPL--------PEDESRSLAANM 546
            ||||||:||.||||||:|.|: .|||::::... .|.|...:||:        ..|||:.....|
 Worm   443 SLAQAALMQGALSKERKETKIQAQRERDMDTQKGFSSNARILDPMSGNQSTAWSADESKDRNNKM 507

  Fly   547 RGMAAAPPEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGET 611
            :       |:|||.|||..|.|:::|::|:|::||||:||||:.|:.:|::|:.|||||:|:|||
 Worm   508 K-------EMPEWLKHVTAGGKATYGRRTNLSMVEQRESLPIFALKKNLMEAMIDNQILVVVGET 565

  Fly   612 GSGKTTQITQYLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPE 676
            |||||||:|||..|.|...|||||||||||||||||||||||||||:||.:||||||||||||.:
 Worm   566 GSGKTTQMTQYAIEAGLGRRGKIGCTQPRRVAAMSVAKRVAEEYGCKLGTDVGYTIRFEDCTSQD 630

  Fly   677 TIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPELKLIVTSATL 741
            ||||||||||||||||::.:|..||:|||||||||||||||||||||.|.:||||||||:|||||
 Worm   631 TIIKYMTDGMLLRECLIDPDLSGYSLIMLDEAHERTIHTDVLFGLLKAAARKRPELKLIITSATL 695

  Fly   742 DAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPGDILLFLTGQEE 806
            |:||||:||.:||||||||||||||:|||:|||:|||:|:.||||||||.|||||:|:|||||||
 Worm   696 DSVKFSEYFLEAPIFTIPGRTFPVEILYTREPESDYLEAAHITVMQIHLTEPPGDVLVFLTGQEE 760

  Fly   807 IDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDG 871
            |||:||:|||||||:|||||||||||||.|||||||||||||||||.||||||||||||||||||
 Worm   761 IDTSCEVLYERMKSMGPDVPELIILPVYGALPSEMQTRIFDPAPAGKRKVVIATNIAETSLTIDG 825

  Fly   872 IFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPT 936
            |||||||||||||:||.|:||||||||||||||||||:||||||||||.||||||||:|||||||
 Worm   826 IFYVVDPGFVKQKIYNPKSGMDSLVVTPISQAAAKQRSGRAGRTGPGKCYRLYTERAFRDEMLPT 890

  Fly   937 PVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDDEGLLTRLGRRM 1001
            |||||||||||:|:||||.||||:|:.||||||||::|::.||..||:|||||.:||||:|||||
 Worm   891 PVPEIQRTNLASTLLQLKAMGINNLIDFDFMDAPPLDSMITALNTLHTLSALDGDGLLTKLGRRM 955

  Fly  1002 AEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALADQKKAKFNQAEGDHLTL 1066
            |||||||:|||:|||||.|.||:|:||||:||:|||:|||||:||..||||||||:|.|||||||
 Worm   956 AEFPLEPSLSKLLIMSVDLGCSEEVLTIVAMLNVQNIFYRPKEKQDHADQKKAKFHQPEGDHLTL 1020

  Fly  1067 LAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDVVSAGKNSVRIQKAICSG 1131
            |||||||||:.||..||:|||:|:|::||:||:|||||||||||||.:||.|::..|:|||||||
 Worm  1021 LAVYNSWKNHHFSQPWCFENFIQVRSMKRAQDIRKQLLGIMDRHKLLMVSCGRDVSRVQKAICSG 1085

  Fly  1132 FFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVE 1196
            |||||||:|||||||||.|.|.||||||||.|.:|||||:|||||.||||||||||.||||||||
 Worm  1086 FFRNAAKRDPQEGYRTLTDGQNVYIHPSSACFQQQPEWVVYHELVMTTKEYMREVTAIDPKWLVE 1150

  Fly  1197 FAPSFFRFSDPTKLSKFKKNQRLEPLYNKYEEPNAWRISRVRRR 1240
            ||||||:..|.||||.||:||:::||::||.:.|||||:||::|
 Worm  1151 FAPSFFKIGDSTKLSTFKRNQKIDPLFDKYADANAWRITRVKKR 1194

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668	32/68 (47%)
		S1_DHX8_helicase	285..363	CDD:240189	43/77 (56%)
		HrpA	578..>1203	CDD:441249	503/624 (81%)
mog-5	NP_495019.1	GH2-like_DHX8	4..73	CDD:409668	32/68 (47%)
		S1_DHX8_helicase	234..311	CDD:240189	43/77 (56%)
		HrpA	538..>1157	CDD:441249	499/618 (81%)