Protein Alignment pea and DHX15

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: NP_001349.2
• Gene: DHX15 / 1665
• HGNCID: 2738
• Length: 795
• Species: Homo sapiens
• Alignment Length: 816
• Identity: 373/816 - (45%)
• Similarity: 503/816 - (61%)
• Gaps: 94/816 - (11%)

  Fly   433 LDRSE-MPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQA 496
            ||..| .|...:..|...||.|.:.|.|                   |.|..|..:...|
Human     7 LDLGEDYPSGKKRAGTDGKDRDRDRDRE-------------------DRSKDRDRERDRG----- 47

  Fly   497 AMMQSALSKERREQKMLQREQEIEAMPTS-LNKNWIDPLPEDES----------------RSLAA 544
                   .:||..:|  ::|:|:.|...: |....:.||....|                .|..|
Human    48 -------DREREREK--EKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHA 103

  Fly   545 NMRGMAAAP---------PEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVT 600
            ...|..:.|         |..|.:                 ..::::|..||:::.:|.....:.
Human   104 GHAGHTSLPQCINPFTNLPHTPRY-----------------YDILKKRLQLPVWEYKDRFTDILV 151

  Fly   601 DNQILIVIGETGSGKTTQITQ----YLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQ 661
            .:|..:::|||||||||||.|    |:.......|| :.|||||||||||||:|||:|....|||
Human   152 RHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRG-VACTQPRRVAAMSVAQRVADEMDVMLGQ 215

  Fly   662 EVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAV 726
            ||||:||||||:|.:||:|||||||||||.:.:..|:.|.||:||||||||:.||:|.|:||..|
Human   216 EVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVV 280

  Fly   727 QKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHL- 790
            ::|.:||:||.||||||.||..||...|:.||||||.|||:.||.|||.|||:|::.||:|||:
Human   281 RQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMC 345

  Fly   791 REPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAP----- 850
            .|..||:|||||||||||.||:.:...:..|||:|.::.|:|:||.||.:.|.|||:|.|
Human   346 EEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQN 410

  Fly   851 -AGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGR 914
             |..||||::||||||||||||:.:|:||||.||||||.:..::||:||.||:|:|:||||||||
Human   411 GAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 475

  Fly   915 TGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMAL 979
            |.|||.:|||||:||:.||.....|||.|:||.:.|||||.:||:||:||||||.|..|:|:.||
Human   476 TRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRAL 540

  Fly   980 EQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKD 1044
            |.|:.|:||:|:|.||.||..||||||:|.|:||:|.|....||:|:|:|.:||||...|.||.:
Human   541 ELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTE 605

  Fly  1045 KQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDR 1109
            .:..||:.|.:|...:|||||||.||:::|.|..|..|||:||:..|:|..:.:||:||..||||
Human   606 AKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDR 670

  Fly  1110 HKLDVVSAGKNS----VRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWV 1170
            ..|...|....|    :.|:||:.:|:|...|..:....|.|:.|:|||.:|||:.| :.:||||
Human   671 FNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWV 734

  Fly  1171 IYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSD 1206
            :|:|.|.|||.|:|..|.|.|:|||:.||.::..|:
Human   735 LYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSN 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	342/639 (54%)
DHX15	NP_001349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		26/133 (20%)
		HrpA	136..>763	CDD:441249	339/628 (54%)
		DEAH box	260..263		2/2 (100%)