DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pea and LOC110438502

DIOPT Version :9

Sequence 1:	NP_610928.1	Gene:	pea / 36561	FlyBaseID:	FBgn0086895	Length:	1242	Species:	Drosophila melanogaster
Sequence 2:	XP_021326722.1	Gene:	LOC110438502 / 110438502	-ID:	-	Length:	511	Species:	Danio rerio

Alignment Length:	544	Identity:	206/544 - (37%)
Similarity:	300/544 - (55%)	Gaps:	63/544 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   682 MTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAVQKRPE-----LKLIVTSATL 741
            |||||||||.:.:..|..|:|::||||||||:|||||||::|.|.::|.|     ||::|.|||:
Zfish     1 MTDGMLLREAIGDPLLLRYTVVILDEAHERTVHTDVLFGVVKAAQRRRLEQNRIPLKVVVMSATM 65

  Fly   742 DAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHLREPPG-DILLFLTGQE 805
            |...|||||.|:|:..:.||..|:::.|||:|::|||.|:|:::.|||...|.. |||:||||||
Zfish    66 DVDLFSQYFNKSPVLYLEGRQHPIQIYYTKQPQSDYLQAALVSIFQIHQEAPSSHDILVFLTGQE 130

  Fly   806 EIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTID 870
            ||:.......:..|.|......:.::|:|::||...|.|:|.|||..|......|: ..|..|:
Zfish   131 EIEALARTCRDISKHLPDTSGSMTVVPLYASLPPAQQMRVFLPAPKVSHTTHTHTH-THTQYTL- 193

  Fly   871 GIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLP 935
                       ||.:.         :.|..:.|.                   |....|.:.:..
Zfish   194 -----------KQSIQ---------IHTHYAHAH-------------------YINMLYCNGVEL 219

  Fly   936 TPVPE-------------IQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSA 987
            ..||:             :.|.|||:.||||..:|:.|:|:|||:..|..||:..|:|||..|.|
Zfish   220 CRVPQAVCSCVCQLYSLCVCRCNLASVVLQLLALGVPDVLNFDFVSKPSPESMRTAVEQLCILGA 284

  Fly   988 L---DDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKDKQALA 1049
            :   ||...||.||::||.|||||..||.|::|....|::|||||:|:|||.:|.|.|..::...
Zfish   285 VDRKDDHVSLTPLGKKMACFPLEPRFSKTLLISPDFSCAEEILTIISLLSVDSVLYNPPARRDEV 349

  Fly  1050 DQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDRHKLDV 1114
            ...:.||..:||||:|||.:|.::|....:..||.||||..|.:....:||.||..|..:..|.:
Zfish   350 ISVRKKFISSEGDHITLLNIYRAFKKVSGNKDWCRENFVNSRNMGLVGEVRAQLRDICIKMNLKL 414

  Fly  1115 VSAGKNSVRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWVIYHELVQTT 1179
            .|:..:...:::.:..|.|.:||:..|...|..|...|.|.|||||.||..:|..|:::||:.|:
Zfish   415 ESSVCDLANVRRCLAHGLFMSAAELQPDGSYVALDTHQPVSIHPSSVLFQARPVCVLFNELLHTS 479

  Fly  1180 KEYMREVTTIDPKWLVEFAPSFFR 1203
            :.|||::..|...||.|.||.:||
Zfish   480 RCYMRDLCLIQTDWLHEAAPEYFR 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	S1_DHX8_helicase	285..363	CDD:240189
pea	NP_610928.1	HrpA	573..1221	CDD:224557	206/544 (38%)
LOC110438502	XP_021326722.1	HrpA	1..496	CDD:224557	201/535 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D354219at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010