Protein Alignment pea and dhx37

DIOPT Version :10

• Sequence 1: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Sequence 2: XP_068078944.1
• Gene: dhx37 / 100009635
• ZFINID: ZDB-GENE-030131-4505
• Length: 1179
• Species: Danio rerio
• Alignment Length: 1132
• Identity: 323/1132 - (28%)
• Similarity: 497/1132 - (43%)
• Gaps: 252/1132 - (22%)

  Fly   283 EAGKIYSGKIANIVPFGCFVQLFG-LRKR--WEGLVHIS--QLRAEGRVTDV------------- 329
            :|..:.:..:..|..|||.....| |||:  |:|....:  |..|..|.|:|
Zfish     5 QAADLETLTLLQISVFGCEELAMGRLRKKHNWKGRQQSTSVQTAAADRQTNVQVEIQDGAVLKGV 69

  Fly   330 ----TEVVTRNQTVKVKVMSITGQKVSLSMKE-------VDQDSGKD-----LNPLSHAPEDDES 378
                ..|:...:|.|.||.....:|.:|:.|:       ::|...|.     |:.|:.....:..
Zfish    70 DDCNALVLPATKTKKQKVERPVTKKKALTKKQRKNLEKVLEQKDKKAHRAEVLSKLAEVQLPEAE 134

  Fly   379 LRDRNPDGPFSSSTSMLNLQGNGMEG-DEHESRKRVTRISSPERWEIKQMISSGVLDRSEMPDFD 442
            |:.........:...:.:::.:..|| |...|..:::.:|...|...::.......:.|||.:..
Zfish   135 LKLLYTTAKLGTGGKLYHIKESVNEGQDGGSSSVKISSLSGANRKRRREADEEEEENESEMSESS 199

  Fly   443 EETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQAAMMQSALSKE- 506
            |:..  ..:|.|.::.|.|.:.||                    |:.:....|..:.:....||
Zfish   200 EDDD--DSEESDSSEEEKEKISEE--------------------KHTEEQQQQQVLKEETKPKEA 242

  Fly   507 -RREQKMLQREQEIEAMPTSLNKNWIDPLPEDESRSLAANMRGMAAAPPEVPEWKKHVIGGKKSS 570
             .:|:|..:...:.:..|.....  ::.|||
Zfish   243 DMKEEKKAETWTKEDCKPAVFIP--VERLPE---------------------------------- 271

  Fly   571 FGKKTDLTLVEQRQSLPIYKLRDDLIKAVTDNQILIVIGETGSGKTTQITQYLGECGFTARGK-I 634
                    :.|.|..||:......:::||.|::.:::.||||||||||:.|:|.|.||.:.|. |
Zfish   272 --------IQEARLRLPVLAEEQIIMEAVKDHECVVLCGETGSGKTTQVPQFLYEAGFASSGGII 328

  Fly   635 GCTQPRRVAAMSVAKRVAEEYGCRLGQEVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKS 699
            |.|:||||||:|::.|||.|.....| .|.|.||:|...:..|.||.||||:||:|...:..|:.
Zfish   329 GVTEPRRVAAISMSHRVATEMNLSSG-VVSYQIRYEGNVTENTKIKVMTDGVLLKEIQRDFLLQK 392

  Fly   700 YSVIMLDEAHERTIHTDVLFGLLKTAVQKRPE----LKLIVTSATLDAVKFSQ----YFFKAPIF 756
            ||||::||||||:::||:|.|||...|..|.:    :|||:.||||....|::    :....|:.
Zfish   393 YSVIIIDEAHERSVYTDILIGLLSRIVPLRNKKGLPMKLIIMSATLRVEDFTENKRLFSSPPPVI 457

  Fly   757 TIPGRTFPVEVLYTKE-PETDYLDASLITVMQIHLREPPGDILLFLTGQEEIDTACEIL------ 814
            .:..|.|.|.|.:.|. |..||...:...:.:||...|||.||:|||||.|:.:.|..|
Zfish   458 KVEARQFAVTVHFNKRTPMDDYTGETFRKICKIHRMLPPGGILVFLTGQAEVHSVCRRLRKAFPY 522

  Fly   815 ------------------YERMK------------------------------------------ 819
                              .:|.|
Zfish   523 KPNREHTDMMETEEDLKKSKRAKKKNVSLPRINLDNYSALPVDEGDEDRQAGIDEDDGEGSDLEL 587

  Fly   820 SLG------------PDVPELIILPVYSALPSEMQTRIFDPAPAGSRKVVIATNIAETSLTIDGI 872
            .||            |.:| |.:||:||.|..|.|.::|.|.|||||..|:|||:|||||||.||
Zfish   588 ELGDHPDTDHEEKADPSIP-LYVLPLYSLLAPEQQAKVFRPPPAGSRLCVVATNVAETSLTIPGI 651

  Fly   873 FYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGRTGPGKTYRLYTERAYRDEMLPTP 937
            .||||.|.||::.|:..||:.|..||.||||:|.|||||||||.||..||||:...:.|..|.:.
Zfish   652 KYVVDCGRVKKRFYDRVTGVSSFKVTWISQASANQRAGRAGRTEPGHCYRLYSSAVFGDFSLFSE 716

  Fly   938 VPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMALEQLHSLSALDD---EGLLTR--- 996
            . ||.|..:...|||:|.:.|..:::|.|...|..|:|:.|.|.|.||.||:.   .|.|:.
Zfish   717 A-EITRRPVEDLVLQMKDLNIEKVVNFPFPTPPSSEALIAAEELLISLGALEKPARHGRLSEMEK 780

  Fly   997 ---------LGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFY---RP---KDKQ 1046
                     |||.||.||:.|..:|||.:.....|...|:||||.::|:.:|.   ||   :::.
Zfish   781 ARLSCPISPLGRAMAAFPVAPRYAKMLALGRQQGCMQYIITIVSAMTVREIFEDYDRPAGSEEEN 845

  Fly  1047 ALADQKKAKFNQAE------------GDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDV 1099
            .....|||:..|..            ||.:.||....:.:....:..:|.||.::.:.:...:.:
Zfish   846 VKMSGKKARSVQMRRLWAGQGASLLLGDLMVLLGAVGACEFAGLTPQFCEENGLRFKAMLEIRRL 910

  Fly  1100 RKQLLGIMDRHKLDVVSAGKNSVR---------IQKAICSGFFRNAAKK-------DP--QEGYR 1146
            |.||...::....|......|.:.         :::.:.:|...:.|::       ||  :..|:
Zfish   911 RGQLTNAVNAVCADADVYVDNKMAPPTEAQVLCLRQIVLAGLGDHIARRVQAEELLDPKWRNAYK 975

  Fly  1147 TLVDSQVVYIHPSSALFNRQPEWVIYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSDPTKLS 1211
            |.:....|:|||||||....||:|:|.|:::|||.|||.|..:...|:.:..|.:..||.|.:
Zfish   976 TPLLDDPVFIHPSSALHKTLPEFVVYQEIMETTKMYMRGVCAVQDDWIPKLLPQYCHFSAPEE-- 1038

  Fly  1212 KFKKNQRLEPLYNK---YEEPNAWRIS 1235
              ....|..||..:   :::...:|:|
Zfish  1039 --SPAPRFCPLIGRVKCHQQSTFFRVS 1063

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189	24/106 (23%)
		HrpA	578..>1203	CDD:441249	260/763 (34%)
dhx37	XP_068078944.1	HrpA	279..>832	CDD:441249	211/555 (38%)
		OB_NTP_bind	944..1030	CDD:400182	28/85 (33%)