Protein Alignment mam and maml1

DIOPT Version :9

• Sequence 1: NP_001286401.1
• Gene: mam / 36555
• FlyBaseID: FBgn0002643
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_005157273.2
• Gene: maml1 / 567335
• ZFINID: ZDB-GENE-100820-2
• Length: 1049
• Species: Danio rerio
• Alignment Length: 1455
• Identity: 316/1455 - (21%)
• Similarity: 443/1455 - (30%)
• Gaps: 571/1455 - (39%)

  Fly   122 DTMPTKRMPVVDRLRRRMENYRRRQTDCVPRYEQAFNTVCEQQNQETTVLQKRFLESKNKRAAKK 186
            |.:..:...|::|||||:|.:||..|.|..||:.......|.:.|:|..||:|||::|.||:.|
Zfish     4 DFVVPRHSAVMERLRRRIELFRRHHTGCENRYDNTAMERLEMERQQTIALQQRFLQTKAKRSNK- 67

  Fly   187 TDKKLPDPSQQHQQQQHQQQQQHQQHQQHQQAQTMLAGQLQSSVHVQQKFLKRPAEDVDNGPDSF 251
                                        |:|.....|.                         |.
Zfish    68 ----------------------------HRQPPAAAAA-------------------------SA 79

  Fly   252 EPPHKLPNNNNNSNSNNNNGNANANNGGNGSNTGNNTNNNGNSTNNNGGSNNNG--SENLTKFSV 314
            :|.                |...|:.||            |::...:|||...|  |.|.|..::
Zfish    80 DPV----------------GQRGASGGG------------GSAEIADGGSGTPGEQSRNSTLIAL 116

  Fly   315 E--IVQQLEFTTSAANSQPQQISTNVTVKALTNTSVKSEPGVGGGGGGGGG-----GGSGNNNNN 372
            :  :.::||   ||.:...:......|.....|.....|..:||..|...|     ......:|.
Zfish   117 QETVKRKLE---SAESPLGRDQVNGFTDGYPPNKKSCVEDAMGGLNGVSNGVVPPLSPLDTKHNV 178

  Fly   373 GGGGGGGNGNNNNNGGDHHQQQHQQQQQQQGGGLGGLGNNGRGGGPGGMATGPGGVAGGLGGMGM 437
            .......|||:...|.:|:                           |......|.|.|.....
Zfish   179 NTDAMMANGNHRVVGSEHN---------------------------GASLKDNGAVRGSESDF-- 214

  Fly   438 PPNMMSAQQKSALGNLANLVECKREPDHDFPDLGSLDKDGGGGQFPGFPDLLGDDNSENNDTFKD 502
                             .|.|.|:||..|  .|..:...||.              :.||..|.|
Zfish   215 -----------------RLKEPKQEPVDD--ALSCILPQGGA--------------NGNNSLFPD 246

  Fly   503 LINNLQDFNPSFLDGFDEK-PLLDIK----TEDGIKVEP----PNAQDLINS--LNVKSEGGLGH 556
            |..|.||:: ..::.|:.. |..||:    ...|.:.:|    ..||.||:.  .|||:|.....
Zfish   247 LNLNDQDWS-EIMEEFNRSVPYEDIQELFSVSFGDRKDPELTSAAAQSLISQDLPNVKTEISPAT 310

  Fly   557 GFGGFGLGLDNPGMKMR---GGNPGNQGGFPNGPNGGTGGA---PNAGGNGGNSGNLMSEHPL-- 613
            ....|.....|...:||   .|.|.:.......|  .|..|   |.....|......:..|.:
Zfish   311 ATSAFEQDSCNGSPQMRPTSSGPPLHTNSPVTAP--ATSPALPVPQHSQQGSIQSRALPNHLMPV 373

  Fly   614 ------AAQTLKQMAEQ----HQHKNAMGGMGGFPRPPHGMNPQQQQQQQQQQ--------QQQQ 660
                  .||.|:|:|:|    |..::.:      .:||....||||..:..||        |...
Zfish   374 PPKDLSPAQQLQQLAQQRAILHSQQHVV------QKPPQQKPPQQQPTKFHQQPSHSTSWPQNAP 432

  Fly   661 AQQQHGQMMGQGQPGRYNDYGGGFPNDFGL---------------------------------GP 692
            .|.|.|...|..:|...:.|...|||...|                                 ||
Zfish   433 TQSQMGGTFGLEKPTSPSLYPQDFPNPKTLLMPNKGSPKAGAPAGYMQPGGHANMLSHPAAPTGP 497

  Fly   693 NGPQQQQQAQQQQPQQQHLPPQFHQQKGPGPGA--GMNVQQNFLDIKQELFYSSQNDFDLKRLQQ 755
            .|......||.......:..|..|...|| |||  |....||         ::..|...|..::|
Zfish   498 LGHPSNPGAQAAMLDFNNTKPLSHYDDGP-PGAPRGPPTTQN---------HNKPNQAILNMMRQ 552

  Fly   756 QQAMQQQQQQQH-------HQQQQQQQQPKMGGVPN----------------------FNKQQQQ 791
            ||..:|:....:       |..|.....|....||.                      :.||||.
Zfish   553 QQIQKQRAPTMNFRPAHLPHTAQDSGSYPPNTHVPGPSNTMTPQTSSNSIPGHHNNPAYLKQQQI 617

  Fly   792 QQVPQQ---QLQQQ----QQQQQQQQQQQQQQYSPFSNQNPNAAANFLNCPPRGGPNGNQQPGNL 849
            |.:.||   |||:|    |::|:|||:||.|::              |..||
Zfish   618 QLMNQQKQFQLQRQIMVEQEKQRQQQEQQLQRH--------------LTRPP------------- 655

  Fly   850 AQQQQQPGAGPQQQQQRGNAANGQQNNPNAGPGGNTPNAPQQQQQQSTTTTLQMKQTQQLHISQQ 914
                      ||.|.|:...|   |.||          ..|||||.|..|::.....||
Zfish   656 ----------PQYQDQQNPQA---QQNP----------FQQQQQQVSQFTSVPPCLAQQ------ 691

  Fly   915 GGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQQQPGGT----NGPNPQQQQ 975
                           |.|...:..:|.|:                  ||.|.    :||.|..|:
Zfish   692 ---------------HTSNFSEHTISGAS------------------QPIGNVNTLSGPAPGTQR 723

  Fly   976 QQPHGGNAGGGVGVGVGVGVGNGGPNPGQQQQQPNQNMSNANVPSDGFSLSQSQSMNFNQQQQQQ 1040
            .   .....|.:|:|||   .|.|||.|     |:...|.|::.....|....|.:.:.......
Zfish   724 M---FSQTQGMMGIGVG---QNAGPNTG-----PSTAASQADMSLPPCSNLDVQQVLYGNISMHA 777

  Fly  1041 AAAQQQQVQPNMRQRQTQAQAAAAAAAAAAQAQAAANASGPNVPLMQQPQVGVGVGVGVGVGVGV 1105
            :.|.||      ||..:...||......|||.||... :.||..|::|.|..:
Zfish   778 SHANQQ------RQPVSTMSAAYRQNVLAAQQQAHLK-NQPNAALLKQQQQQL------------ 823

  Fly  1106 GNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQMGGPMNPMQMNPNAAGPTAQQMMMGSGAGGPG 1170
                      :..|||.|                    |.|..|..:|.||:....:      ||
Zfish   824 ----------ARLPNNMA--------------------NAMSNNMGSAMPTSMPTSI------PG 852

  Fly  1171 QVPGPGQGPNPNQAKFLQQQQMMRAQAMQQQQQHMSGARPPPPEYNATKAQLMQAQMMQQTVGGG 1235
            .:|                   ::||:.|||         ||.::.|.::
Zfish   853 ALP-------------------VQAQSWQQQ---------PPQQHPALQS--------------- 874

  Fly  1236 GVGVGGVGVGVGVGGVGGANGGRFPNSAAQAAAMRRMTQQPIPPSGPMMRPQHAMYMQQHGGAGG 1300
                         |...||....||||:....:  |:|:  :|.:.|.
Zfish   875 -------------GSANGAMPAGFPNSSFHMQS--RLTK--LPNNTPF----------------- 905

  Fly  1301 GPRTGMGVPYGGGAGGPMGG--PQQQQRPPNVQVTPD-GMPMGSQQEWRHMMMTQQQTQMGFGGP 1362
             |:.|||   ...||..|||  |.|.....|.|.|.: |||   ||....:..|.||.|
Zfish   906 -PQGGMG---NSAAGRTMGGMNPGQMMTNMNQQRTNNPGMP---QQLPPPVQQTAQQGQ------ 957

  Fly  1363 GPGGPMRQ-------GPGGFNGGNFMPNGAP----------NGAAGS------GPNAGGMMSGPN 1404
             |..|.:.       ||  |:....:||...          |.||..      ...:||.:||
Zfish   958 -PQAPPQTQQVLPDLGP--FSQAQAVPNRTTGLQCNQAYQLNRAANQQLQFSYNTQSGGSLSG-- 1017

  Fly  1405 VPQMQLTPAQ--MQQQLMRQQQQQQ 1427
                  .||:  :...|::.|..||
Zfish  1018 ------FPAETDLVDSLLKDQSTQQ 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mam	NP_001286401.1	MamL-1	127..183	CDD:286652	23/55 (42%)
maml1	XP_005157273.2	MamL-1	8..65	CDD:286652	23/56 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4577
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.050