Protein Alignment mam and Maml1

DIOPT Version :9

• Sequence 1: NP_001286401.1
• Gene: mam / 36555
• FlyBaseID: FBgn0002643
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_006246313.2
• Gene: Maml1 / 303101
• RGDID: 1308631
• Length: 1017
• Species: Rattus norvegicus
• Alignment Length: 1235
• Identity: 265/1235 - (21%)
• Similarity: 374/1235 - (30%)
• Gaps: 465/1235 - (37%)

  Fly   116 VPTAPGDTMPTKRMP----VVDRLRRRMENYRRRQTDCVPRYEQAFNTVCEQQNQETTVLQKRFL 176
            :||.|   |....:|    |::|||||:|..||..:.|..|||.......|.:.|.|..|.:|.:
  Rat     3 LPTCP---MAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCI 64

  Fly   177 ESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQHQQAQTMLAGQLQSSVHVQQKFLKRPA 241
            ::|.|||.|                          |:|...|.|..|.....:        ..||
  Rat    65 QAKAKRAGK--------------------------HRQPPAAATAPAAAPAPA--------PAPA 95

  Fly   242 E---DVDNGPDSFEPPHKLPNNNNNSNSNNNNGNANANNGGNGSNTGNNTNNNGNSTNNNGGSNN 303
            .   |..:||:...|...|
  Rat    96 AARLDSADGPEHGRPVAHL---------------------------------------------- 114

  Fly   304 NGSENLTKFSVEIVQQLEFTTSAANSQPQQISTNVTVKALTNTSVKSEPGVGGGGGGGGGGGSGN 368
               .:..|.|::         |||:.|
  Rat   115 ---HDPVKRSLD---------SAASPQ-------------------------------------- 129

  Fly   369 NNNNGGGGGGGNGNNNNNGGD---HHQQQHQQQQQQQGGGLGGLGNNGRGGGPGGMATGPGGVAG 430
                       ||:..|..||   .|::..::..........||......|.|.....|.....|
  Rat   130 -----------NGDQPNGYGDLFPGHKKTRREAPLGVSVSANGLPPASPLGQPDKPPVGDALQTG 183

  Fly   431 GLGGMGMPP-----------NMMSAQQKSALGNLANLVECKREPDHDFPDLGSLDKDGGGGQFPG 484
            |...:|:.|           ::......|....|:...|.|:||..|.|.:     ..|.|....
  Rat   184 GKHSLGLDPINKKCLADSSIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCM-----IAGAGSSVA 243

  Fly   485 FPDLLGDDNSENNDTFKDLINNL------QDFNPSFLDGFDEKPLLDIKTED--GIKVEPPNAQD 541
            ..:|:.|.|. |...:|:||..|      :|....|.:.|:||     |..:  |...:.|.|||
  Rat   244 QSNLMPDLNL-NEQEWKELIEELNRSVPDEDMKDLFTEDFEEK-----KDPEPPGSATQTPLAQD 302

  Fly   542 LINSLNVKSE------------------GGLGHGF---GGFGLGLDNPGMKMRG---------GN 576
                :|:|:|                  |..|..|   ....:|.|:|.:   |         |.
  Rat   303 ----INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLAPSSAPVGTDSPSL---GNSQTLFHTTGQ 360

  Fly   577 PGNQGGFP----------NGPNGGTGGAPNAGGNGGNSGNLMSEHPL----AAQTLKQMAEQHQH 627
            ||.....|          |.|...|.....:.|.||.| .|.|.|.|    |.|..:||.:..|.
  Rat   361 PGVDSSSPNLMPASAQAQNAPRALTSVVLPSQGPGGAS-ELSSAHQLQQIAAKQKREQMLQNPQQ 424

  Fly   628 KNAMGGMGGF---------------------PRPPHG-----------MNPQQQQQQQQQQQQQQ 660
            .....|.|..                     |..|.|           |.| ...:...:.....
  Rat   425 TAPAPGPGQLSTWQQAGPSHSPLDAPYPMEKPASPSGYKQDFTNSKLLMMP-SVNKSSPRPGGPY 488

  Fly   661 AQQQHGQMMGQGQPGRYN-----------DYGGGFP-----NDFGLGPNG------------PQQ 697
            .|..|..::....|...|           |||...|     .|.|.|..|            |||
  Rat   489 LQPSHSNLLSHQSPSNLNPNPVNNQGSMLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQ 553

  Fly   698 QQQAQQQQ-------------PQQQHLPPQFHQQKG----PGPGAGMNVQQNFLDIKQELFYSSQ 745
            ......:|             |.:..:||...|...    |.|.|.:..|.:       :..:|.
  Rat   554 LPHLSNEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVPAPAASVGTQPS-------VSVAST 611

  Fly   746 NDFDLKRLQQQQAMQQQQQQQHHQQQQQQQQPKMGGVPNFNKQQQQQQVPQQQLQQQQQQQQQQQ 810
            :.......|||.|:.:|.|....||:|::||          :.||||.:.:|.|..:|::||.|:
  Rat   612 HSSSYLSSQQQAAVMKQHQLLLDQQKQREQQ----------QLQQQQFLQRQHLLAEQEKQQFQR 666

  Fly   811 -------QQQQQQYSPFSNQ-----NPNAAANFLN--------CP---PRGGPNGNQQPGNLAQQ 852
                   |.|....|.|..|     .|:||...:|        ||   |:.|...:..||:....
  Rat   667 HLTRPPPQYQDPTQSTFQQQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVS 731

  Fly   853 QQQPGAGPQQQQQRGNAA-NGQQNNPNAGPGGNTPNAPQ---QQQQQSTTTTLQMKQTQQLHISQ 913
            ...|.:|   ||.||.|. .|.|:.|:....|......|   |...|:|:|        ..||.:
  Rat   732 SLPPSSG---QQDRGVAQFTGSQSLPHNSLYGMASGLAQIVAQPPPQATST--------HAHIPR 785

  Fly   914 QGGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGVFFSQQQAQQQQQQQQPGGTNGPNPQQQQQQP 978
                    |.:.||:        ::.|.|..|....|...:||..:...|.|...|      |.|
  Rat   786 --------QTNVGQN--------ASTSAAYGQNSLGSASLSQQHSKGTLPPGLAKP------QVP 828

  Fly   979 HGGNAGGGVGVGVGVGVGNGGPNPG-QQQQQPN---QNMSNANVPSDGFSLSQSQSMNFNQQQQ- 1038
            .             |....|..||. |.|..||   |...|::|  ..|:.:.|    |::||.
  Rat   829 R-------------VSAAMGSQNPSWQHQGMPNLSSQTPGNSSV--SPFTAASS----FHRQQAH 874

  Fly  1039 -QQAAAQQQQVQPNMRQRQTQAQAAAAAAAAAAQAQAAANASGPNVPLMQQPQVGVGVGVGVGVG 1102
             :.:|.|..|..|      |:..|..::||||          ||.:|.:...|..
  Rat   875 LKMSAQQFSQAMP------TRPMAPLSSAAAA----------GPMLPSVSTQQRN---------- 913

  Fly  1103 VGVGNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGMQMGGPMNPMQMNPNAAGPTAQQMMMGSGAG 1167
                     ..|....|.  |.:|.     |:||:...||    ::......||:|   |.|..|
  Rat   914 ---------SAPAPAPPQ--AASQQ-----GLPGLSPSGP----ELGAFGQSPTSQ---MNSRPG 955

  Fly  1168  1167
              Rat   956  955

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mam	NP_001286401.1	MamL-1	127..183	CDD:286652	21/59 (36%)
Maml1	XP_006246313.2	MamL-1	14..71	CDD:401509	21/56 (38%)
		PAT1	<368..>566	CDD:401645	40/199 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000