Protein Alignment mam and Maml1

DIOPT Version :9

• Sequence 1: NP_001286401.1
• Gene: mam / 36555
• FlyBaseID: FBgn0002643
• Length: 1594
• Species: Drosophila melanogaster
• Sequence 2: XP_006531981.1
• Gene: Maml1 / 103806
• MGIID: 1890504
• Length: 1060
• Species: Mus musculus
• Alignment Length: 1268
• Identity: 273/1268 - (21%)
• Similarity: 386/1268 - (30%)
• Gaps: 485/1268 - (38%)

  Fly   116 VPTAPGDTMPTKRMP----VVDRLRRRMENYRRRQTDCVPRYEQAFNTVCEQQNQETTVLQKRFL 176
            :||.|   |....:|    |::|||||:|..||..:.|..|||.......|.:.|.|..|.:|.:
Mouse     3 LPTCP---MAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCI 64

  Fly   177 ESKNKRAAKKTDKKLPDPSQQHQQQQHQQQQQHQQHQQHQQAQTM-LAGQLQSSVHVQQKFLKRP 240
            ::|.|||.|                          |:|...|.|. :|....:|.....:.
Mouse    65 QAKAKRAGK--------------------------HRQPPAAATAPVAAPAPASAPAAARL---- 99

  Fly   241 AEDVDNGPDSFEP---------PHKLPNNNNNSNSNNNNGNANANNGGNGSNTGNNTNNNGNSTN 296
              |..:||:...|         || .|                     ....|..||
Mouse   100 --DAADGPEHGRPVAGYCFPSFPH-YP---------------------RCETTRQNT-------- 132

  Fly   297 NNGGSNNNGSENLTKFSVEIVQQLEFTTSAANSQP-----QQISTNVTVKALTNTSVKSEPGVGG 356
                             ..:.|.||      :|.|     :....:.|||...:::...:
Mouse   133 -----------------PVLTQLLE------SSHPHFPACKSRHLHDTVKRSLDSAASPQ----- 169

  Fly   357 GGGGGGGGGSGNNNNNGGGGGGGNGNNNNNGGDHHQQQHQQQQQQQGGGLGGLGNNGRGGGPGGM 421
                                   ||:..|..||.. ..|::.:::...|:....|......|.|.
Mouse   170 -----------------------NGDQPNGYGDLF-PGHKKTRREAPLGVSVSANGLPPASPLGQ 210

  Fly   422 ATGPGG----VAGGLGGMGMPP-----------NMMSAQQKSALGNLANLVECKREPDHDFPDLG 471
            ...|.|    ...|...:|:.|           ::......|....|:...|.|:||..|.|.:.
Mouse   211 PDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMI 275

  Fly   472 SLDKDGGGG---QFPGFPDLLGDDNSENNDTFKDLINNL------QDFNPSFLDGFDEKPLLDIK 527
            :    |.||   |....|||     :.|...:|:||..|      :|....|.:.|:||     |
Mouse   276 A----GAGGSVAQSNLMPDL-----NLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEK-----K 326

  Fly   528 TED--GIKVEPPNAQDLINSLNVKSE------------------GGLGHGFGGFG---LGLDNPG 569
            ..:  |...:.|.|||    :|:|:|                  |..|..|.|..   :|.|:|.
Mouse   327 DPEPPGSATQTPLAQD----INIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGASSAPVGTDSPS 387

  Fly   570 MKMRGGN---------PGNQGGFPN-------------------GPNGGTGGAPNAGGNGGNSGN 606
            :   |.:         ||.....||                   .|:.|.|||          ..
Mouse   388 L---GSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGA----------SE 439

  Fly   607 LMSEHPL----AAQTLKQMAEQHQHKNAMGGMGGFPR-----PPHG----MNPQQQQQQQQQQQQ 658
            |.|.|.|    |.|..:||.:..|......|.|....     |.|.    ..|.::.......:|
Mouse   440 LSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQ 504

  Fly   659 Q----------------------QAQQQHGQMMGQGQPGRYN-----------DYGGGFP----- 685
            .                      ..|..|..::....|...|           |||...|
Mouse   505 DFTNSKLLMMPGVNKSSPRPGGPYLQPSHSNLLSHQSPSNLNQNPVNNQGSVLDYGNTKPLSHYK 569

  Fly   686 NDFGLGPNG------------PQQQQQAQQQQ-------------PQQQHLPPQFHQQKGP---- 721
            .|.|.|..|            |||......:|             |.:..:||  .|::.|
Mouse   570 ADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPP--GQEQNPSSVP 632

  Fly   722 --GPGAGMNVQQNFLDIKQELFYSSQNDFDLKRLQQQQAMQQQQQ---QQHHQQQQQQQQPKMGG 781
              .|.|.:..|...      ...|:.|.......|||.|:.:|.|   .|..|::|||||
Mouse   633 VAAPAASVGTQPTV------SVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQ----- 686

  Fly   782 VPNFNKQQQQQQVPQQQLQQQQQQQQQQQ-------QQQQQQYSPFSNQ-----NPNAAANFLNC 834
                  .||||.:.:|.|..:|::||.|:       |.|....|.|..|     .|:||...:|
Mouse   687 ------LQQQQFLQRQHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFPQQVGQFTGPSAAVPGMN- 744

  Fly   835 PPRGGPNGNQ------QPGNLAQQQQQPGAGP-------QQQQQRGNAA-NGQQNNPNAGPGGNT 885
              ..||:.:.      |||.|  ....||..|       ..||.||.|. .|.|:.|.....|..
Mouse   745 --NLGPSNSSCPRVFPQPGTL--MSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYGMA 805

  Fly   886 PNAPQ---QQQQQSTTTTLQMKQTQQLHISQQGGGAHGIQVSAGQHLHLSGDMKSNVSVAAQQGV 947
            ....|   |...|:|:|        ..||.:        |.:.||:        ::.|.|..|..
Mouse   806 SGLAQIVAQPPPQATST--------HAHIPR--------QTNVGQN--------ASTSAAYGQNS 846

  Fly   948 FFSQQQAQQQQQQQQPGGTNGPNPQQQQQQPHGGNAGGGVGVGVGVGVGNGGPNPGQQQQQPN-- 1010
            ..|...:||..:...|.|...|      |.|.         |...:|..|..   .|.|..||
Mouse   847 LGSASLSQQHSKGTLPPGLTKP------QVPR---------VSAAMGSQNAS---WQHQGMPNLS 893

  Fly  1011 -QNMSNANVPSDGFSLSQSQSMNFNQQQQQQAAAQQQ--QVQPNMRQRQTQAQAAAAAAAAAAQA 1072
             |...|::|  :.|:.:.|    |:.||.....|.||  |..|      ::..|..::|.||
Mouse   894 SQTSGNSSV--NPFTAAPS----FHIQQAHLKLAGQQFSQAMP------SRPMAPLSSAGAA--- 943

  Fly  1073 QAAANASGPNVPLMQQPQVGVGVGVGVGVGVGVGNGGVVGGPGSGGPNNGAMNQMGGPMGGMPGM 1137
                   ||.:|.:...|..                   ..|.|..|       ...|..|:||:
Mouse   944 -------GPMLPPVSAQQRN-------------------SAPASAPP-------QAAPQQGLPGL 975

  Fly  1138 QMGGPMNPMQMNPNAAGPTAQQMMMGSGAGGPG 1170
            ...||    ::......||:|.      :|.||
Mouse   976 SPSGP----ELGAFGQSPTSQM------SGRPG 998

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mam	NP_001286401.1	MamL-1	127..183	CDD:286652	21/59 (36%)
Maml1	XP_006531981.1	MamL-1	14..71	CDD:370574	21/56 (38%)
		PAT1	<411..>606	CDD:370676	36/204 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000